Protein Alignment CG12746 and SGPP2

DIOPT Version :10

• Sequence 1: NP_649551.4
• Gene: CG12746 / 40672
• FlyBaseID: FBgn0037341
• Length: 363
• Species: Drosophila melanogaster
• Sequence 2: NP_689599.2
• Gene: SGPP2 / 130367
• HGNCID: 19953
• Length: 399
• Species: Homo sapiens
• Alignment Length: 201
• Identity: 48/201 - (23%)
• Similarity: 73/201 - (36%)
• Gaps: 52/201 - (25%)

  Fly   118 GELLFWVIVAPFLVTIAFYWYTRDRRDFRAASWAWTLALCMNGIPTSVLKITVGRPRPDYFYRCF 182
            |:.:|::...||.     :| ..|....|.....|.|.:.:..:...|||    .|||.     .
Human    97 GQEVFYITFLPFT-----HW-NIDPYLSRRLIIIWVLVMYIGQVAKDVLK----WPRPS-----S 146

  Fly   183 PDGVMVLNTTSNGVDTSILDFNCTGLPGDINEGRKSFPSGHSSFAFASFGFIAYYIGAKLHAFDS 247
            |..|.:....       |.::              ..||.|:..|.|    ||:.:  .:...|.
Human   147 PPVVKLEKRL-------IAEY--------------GMPSTHAMAATA----IAFTL--LISTMDR 184

  Fly   248 RGRGHTWRLCIAVIPLFIALLVAVSRTCDYHHHWQDVTIGGLIGLFAGYISYTQYYPS---IFCP 309
            ........|.:||:   .:.||.:||.....|...|| :||:: :.|..|..|  ||:   |.|.
Human   185 YQYPFVLGLVMAVV---FSTLVCLSRLYTGMHTVLDV-LGGVL-ITALLIVLT--YPAWTFIDCL 242

  Fly   310 DAGIPL 315
            |:..||
Human   243 DSASPL 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12746	NP_649551.4	PAP2_containing_1_like	104..302	CDD:239484	41/183 (22%)
SGPP2	NP_689599.2	PAP2_SPPase1	84..233	CDD:239482	41/184 (22%)
		Phosphatase sequence motif I. /evidence=ECO:0000305	136..144		4/11 (36%)
		Phosphatase sequence motif II. /evidence=ECO:0000305	163..166		2/2 (100%)
		Phosphatase sequence motif III. /evidence=ECO:0000305	206..217		3/10 (30%)