| Sequence 1: | NP_730944.2 | Gene: | Pi4KIIalpha / 40670 | FlyBaseID: | FBgn0037339 | Length: | 710 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_060793.2 | Gene: | PI4K2B / 55300 | HGNCID: | 18215 | Length: | 481 | Species: | Homo sapiens |
| Alignment Length: | 592 | Identity: | 273/592 - (46%) |
|---|---|---|---|
| Similarity: | 345/592 - (58%) | Gaps: | 142/592 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 130 DDEDGEEAVLLKRS--SNPRNQRLKGSAEDSIDSSSQQPPIICHIAPAKVASSALTSPLKTTSHT 192
Fly 193 ALARHPHDEADDICLVPEIDFEGMSTDAGSDNRESQPLLGGGNASHGSRISELLGGLGRGHDHVE 257
Fly 258 FVSNTFGDDPLFSEIVAKAEGAIENGVLPERIYQGSSGSYFVKDASHQCLAVFKPKDEEPYGRLN 322
Fly 323 PKWTKWMHKLCCPCCFGRACLIPNQGYLSESGASLVDRKLNLNVVPKTRVVRLVAESFNYARIDR 387
Fly 388 QKAKLKKRIKEHYPSA--HFNRMSLPLKTGSFQLFVEGYKDADYWLRRFESEPLPPSVAKSFQLQ 450
Fly 451 FERLVVLDYIIRNTDRGNDNWLIKYVAPKITTQVGGTGGRTMHGVVTPKLPNALGASKIVDLNEP 515
Fly 516 PQASPKPTTGGRPSNHLAGGAATSAQQDSSSLASSEDEPSSRSPPTSEPDWNVVNSAFIRIAAID 580
Fly 581 NGLAFPFKHPDSWRAYPYHWAWLPQAKIPFSEEIKEQVLPQLSDMNFVEEICTELLYLFQQDRGF 645
Fly 646 DKRLFERQMSVMRGQILNLTQALRDGKSPVQLVQMPAVIVERSSG---SRFF----SFTQRFQNK 703
Fly 704 SPFF-SW 709 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Pi4KIIalpha | NP_730944.2 | PKc_like | 293..>474 | CDD:304357 | 126/182 (69%) |
| PI4K2B | NP_060793.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..82 | 18/96 (19%) | |
| PI3_PI4_kinase | 130..427 | CDD:278861 | 196/371 (53%) | ||
| Important for substrate binding. /evidence=ECO:0000250|UniProtKB:Q9BTU6 | 153..155 | 1/1 (100%) | |||
| Important for interaction with membranes. /evidence=ECO:0000250|UniProtKB:Q9BTU6 | 161..174 | 9/12 (75%) | |||
| Important for interaction with membranes. /evidence=ECO:0000250|UniProtKB:Q9BTU6 | 264..272 | 5/7 (71%) | |||
| Important for interaction with membranes. /evidence=ECO:0000250|UniProtKB:Q9BTU6 | 357..366 | 7/8 (88%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165147217 | |
| Domainoid | 1 | 1.000 | 432 | 1.000 | Domainoid score | I591 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG2381 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 516 | 1.000 | Inparanoid score | I1300 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0002168 | |
| OrthoInspector | 1 | 1.000 | - | - | otm41008 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101496 | |
| Panther | 1 | 1.100 | - | - | O | PTHR12865 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1894 |
| SonicParanoid | 1 | 1.000 | - | - | X1639 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 13 | 12.780 | |||||