Protein Alignment LYN and lyn

DIOPT Version :9

• Sequence 1: XP_011515831.1
• Gene: LYN / 4067
• HGNCID: 6735
• Length: 682
• Species: Homo sapiens
• Sequence 2: XP_012820235.2
• Gene: lyn / 549989
• XenbaseID: XB-GENE-1015126
• Length: 508
• Species: Xenopus tropicalis
• Alignment Length: 501
• Identity: 413/501 - (82%)
• Similarity: 447/501 - (89%)
• Gaps: 23/501 - (4%)

Human   182 PHTQVLLGRPVAPPTLNSSHRGAPPPRNFHRERVPESQLLPGQRFQTKDPEEQGDIVVALYPYDG 246
            |.....|.|||:                    |.|  .|||||:. .::.||||:||:|||||.|
 Frog    31 PDPTAKLQRPVS--------------------RTP--SLLPGQKI-LQEIEEQGNIVIALYPYQG 72

Human   247 IHPDDLSFKKGEKMKVLEEHGEWWKAKSLLTKKEGFIPSNYVAKLNTLETEEWFFKDITRKDAER 311
            ||.|||:||||||:||:||||||||||||.|||||||||||||::||||||||||||||||||||
 Frog    73 IHQDDLTFKKGEKLKVIEEHGEWWKAKSLSTKKEGFIPSNYVARVNTLETEEWFFKDITRKDAER 137

Human   312 QLLAPGNSAGAFLIRESETLKGSFSLSVRDFDPVHGDVIKHYKIRSLDNGGYYISPRITFPCISD 376
            |||||||:.||||||||||.|||:|||:||:||..||||||||||:||||||||||||||..|.|
 Frog   138 QLLAPGNNPGAFLIRESETSKGSYSLSIRDYDPKTGDVIKHYKIRTLDNGGYYISPRITFTSICD 202

Human   377 MIKHYQKQADGLCRRLEKACISPKPQKPWDKDAWEIPRESIKLVKRLGAGQFGEVWMGYYNNSTK 441
            ||:|||||||||||:|:|.|.||||||||||||||||||||||||:||||||||||||:||||||
 Frog   203 MIQHYQKQADGLCRKLDKPCYSPKPQKPWDKDAWEIPRESIKLVKKLGAGQFGEVWMGFYNNSTK 267

Human   442 VAVKTLKPGTMSVQAFLEEANLMKTLQHDKLVRLYAVVTREEPIYIITEYMAKGSLLDFLKSDEG 506
            ||||||||||||||||:|||||||:|||||||||||||::|||||||||:|||||||||||||||
 Frog   268 VAVKTLKPGTMSVQAFMEEANLMKSLQHDKLVRLYAVVSKEEPIYIITEFMAKGSLLDFLKSDEG 332

Human   507 GKVLLPKLIDFSAQIAEGMAYIERKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTARE 571
            .||:|||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||
 Frog   333 AKVILPKLIDFSAQIAEGMAYIEKKNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTARE 397

Human   572 GAKFPIKWTAPEAINFGCFTIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMTALSQGYRMPRVE 636
            |||||||||||||||||.|||||||||||:|||||:|.|||||||.:|:||||||.:||||||:|
 Frog   398 GAKFPIKWTAPEAINFGSFTIKSDVWSFGVLLYEIITTGKIPYPGMSNSDVMTALQRGYRMPRME 462

Human   637 NCPDELYDIMKMCWKEKAEERPTFDYLQSVLDDFYTATEGQYQQQP 682
            |||.|||||||.|||||||||||||||||||||||||||.||||||
 Frog   463 NCPVELYDIMKECWKEKAEERPTFDYLQSVLDDFYTATEAQYQQQP 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LYN	XP_011515831.1	SH3_Lyn	237..292	CDD:212937	46/54 (85%)
		SH2_Src_Lyn	295..395	CDD:198227	84/99 (85%)
		PTKc_Lyn	409..680	CDD:270657	247/270 (91%)
		Pkinase_Tyr	417..667	CDD:285015	227/249 (91%)
lyn	XP_012820235.2	SH3_Lyn	63..118	CDD:212937	46/54 (85%)
		SH2_Src_Lyn	121..221	CDD:198227	84/99 (85%)
		PTKc_Lyn	235..506	CDD:270657	247/270 (91%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	470	1.000	Domainoid score	I4306
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H55649
Inparanoid	1	1.050	878	1.000	Inparanoid score	I3838
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D102936at32523
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	1	1.000	-	-		oto153379
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11610
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.060