Protein Alignment Snm1 and PSO2

DIOPT Version :10

• Sequence 1: NP_649548.1
• Gene: Snm1 / 40669
• FlyBaseID: FBgn0037338
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: NP_013857.1
• Gene: PSO2 / 855168
• SGDID: S000004745
• Length: 661
• Species: Saccharomyces cerevisiae
• Alignment Length: 663
• Identity: 165/663 - (24%)
• Similarity: 262/663 - (39%)
• Gaps: 183/663 - (27%)

  Fly    89 SAVKNYKVKSSSSCRKVDPPLDKRKVSTKGRKRLFEESTTTSSAFTGKLDAKPSE---KRVQPSR 150
            |.||..:..::||..:..........|:|.::.|.|.:..|||    .|..:.|.   .|...|.
Yeast    12 SEVKRKRSSTASSTSEGKTLHKNTHTSSKRQRTLTEFNIPTSS----NLPVRSSSYSFSRFSCST 72

  Fly   151 RAKGKENASLSEVHVIDLCSED----EQTIKRKPSAIASPCEKSSDVQATKFRTPETSMPEAK-- 209
            ..|..|...:::.....:|.||    |.||......:.|  ...::|.|.:.||.:..:.|.:
Yeast    73 SNKNTEPVIINDDDHNSICLEDTAKVEITIDTDEEELVS--LHDNEVSAIENRTEDRIVTELEEQ 135

  Fly   210 ---------------LSN-SSLDLVE--------ISPGPNK--SPTNNF--YRSSPAAITKESPL 246
                           |.| |.|:|.|        |...|:.  :|..|.  :.|:|::..|....
Yeast   136 VNVKVSTEVIQCPICLENLSHLELYERETHCDTCIGSDPSNMGTPKKNIRSFISNPSSPAKTKRD 200

  Fly   247 GKNSKKGTVRKQRKPKPCPPYKVVE---GTSFCVDGFQFGEIEGVTHYFLTHFHADHYIGLTKKF 308
            ...|||.|    |.....|.:|:::   |....||||.:...|.::.|||:|||:||||||.|.:
Yeast   201 IATSKKPT----RVKLVLPSFKIIKFNNGHEIVVDGFNYKASETISQYFLSHFHSDHYIGLKKSW 261

  Fly   309 CHP--------LYVSPISARLVRTFIKLDETHIHEIDVDQTLDV-DGVQVTALEANHCPGALMFF 364
            .:|        ||.|.|:|.||....|:....|..:.:::...: |.:.|..|:|||||||::..
Yeast   262 NNPDENPIKKTLYCSKITAILVNLKFKIPMDEIQILPMNKRFWITDTISVVTLDANHCPGAIIML 326

  Fly   365 FK--LSSG-----ECILHTGDFRASADMESLPIFW----NHSNIDLLYLDTTYMNKNYDFCHQSE 418
            |:  |::.     ..||||||||::|.|......|    .:..||.:|||||||...|:|..|..
Yeast   327 FQEFLANSYDKPIRQILHTGDFRSNAKMIETIQKWLAETANETIDQVYLDTTYMTMGYNFPSQHS 391

  Fly   419 SVDRAVDLVRAFLEKNAAK-----------------------RILIVCGSYVIGKEKIWLALAK- 459
            ..:...|.....::....|                       |:|.:.|:|.|||||:.:.:.:
Yeast   392 VCETVADFTLRLIKHGKNKTFGDSQRNLFHFQRKKTLTTHRYRVLFLVGTYTIGKEKLAIKICEF 456

  Fly   460 ------------EFTMRVWTESNRSTAVRCLNWPDL--DSVLTEDRSGANLHVIAMGKISYPSLV 510
                        :|:|.:....|..      |..|:  :|:||.:...:::|::.:..:.....:
Yeast   457 LKTKLFVMPNSVKFSMMLTVLQNNE------NQNDMWDESLLTSNLHESSVHLVPIRVLKSQETI 515

  Fly   511 ------------DYFTEFEDQYDMLLGIRPSGWEKNSKPSYGKR--------------------- 542
                        ||..:.||    ::|..|:||..|....|.|:
Yeast   516 EAYLKSLKELETDYVKDIED----VVGFIPTGWSHNFGLKYQKKNDDDENEMSGNTEYCLELMKN 576

  Fly   543 -----------ISTI-------------GIEYSEHSSYKELERFVRFLKPKRVISTVPVG---RD 580
                       ||:|             .:.||||||:.:|.:|...||...||.||.:.   :.
Yeast   577 DRDNDDENGFEISSILRQYKKYNKFQVFNVPYSEHSSFNDLVKFGCKLKCSEVIPTVNLNNLWKV 641

  Fly   581 LYVTGEVPIRWYK 593
            .|:|     .|::
Yeast   642 RYMT-----NWFQ 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snm1	NP_649548.1	SNM1A-1C-like_MBL-fold	252..408	CDD:293831	65/178 (37%)
		DRMBL	481..578	CDD:429512	33/155 (21%)
PSO2	NP_013857.1	SNM1A-1C-like_MBL-fold	202..380	CDD:293831	66/181 (36%)
		DRMBL	488..637	CDD:429512	32/152 (21%)