Protein Alignment Snm1 and YSH1

DIOPT Version :10

• Sequence 1: NP_649548.1
• Gene: Snm1 / 40669
• FlyBaseID: FBgn0037338
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: NP_013379.1
• Gene: YSH1 / 850983
• SGDID: S000004267
• Length: 779
• Species: Saccharomyces cerevisiae
• Alignment Length: 697
• Identity: 125/697 - (17%)
• Similarity: 222/697 - (31%)
• Gaps: 259/697 - (37%)

  Fly   265 PPYKVVEGTSFCVDGFQFGEIEGVTHYFLTHFHADH-----YIGLTKKF------CHPLYVSPIS 318
            |.|:.:....| .|.|...:::.:   .::|||.||     |:.....|      .||  ...|.
Yeast    42 PAYQGLASLPF-YDEFDLSKVDIL---LISHFHLDHAASLPYVMQRTNFQGRVFMTHP--TKAIY 100

  Fly   319 ARLVRTFIKL-------------------DE------THIHEIDVDQTLDVDGVQVTALEANHCP 358
            ..|:|.|:::                   ||      ..|..:|...|:||:|::.||..|.|..
Yeast   101 RWLLRDFVRVTSIGSSSSSMGTKDEGLFSDEDLVDSFDKIETVDYHSTVDVNGIKFTAFHAGHVL 165

  Fly   359 GALMFFFKLSSGECILHTGDFRASAD--MESLPIFWNHSNIDLLYLDTTYMNKNYD--------- 412
            ||.||..:: :|..:|.|||:....|  :.|..:....||:  |.:::|:....::
Yeast   166 GAAMFQIEI-AGLRVLFTGDYSREVDRHLNSAEVPPLSSNV--LIVESTFGTATHEPRLNRERKL 227

  Fly   413 --FCHQSESVDRAVDLVRAFLEKNAAKRILIVCGSYVIGKEKIWLALAKEF---TMRVWTESNRS 472
              ..|  .:|.|...::........|:.|:::...|       |...|.|.   .:.::..||.:
Yeast   228 TQLIH--STVMRGGRVLLPVFALGRAQEIMLILDEY-------WSQHADELGGGQVPIFYASNLA 283

  Fly   473 --------TAVRCLNWPDLDSVLTEDRSGANLHVIAMGKISYPSLVDYFTEFEDQYDMLL--GIR 527
                    |.|..:|    |.:..:.|. :..:......|||...::.|.:|.... ||.  |:.
Yeast   284 KKCMSVFQTYVNMMN----DDIRKKFRD-SQTNPFIFKNISYLRNLEDFQDFGPSV-MLASPGML 342

  Fly   528 PSG--------W-------------------------EKNSKPSYG-------KRISTIGIEYSE 552
            .||        |                         |.::.||..       :|.....|.::.
Yeast   343 QSGLSRDLLERWCPEDKNLVLITGYSIEGTMAKFIMLEPDTIPSINNPEITIPRRCQVEEISFAA 407

  Fly   553 HSSYKELERFVRFLKPKRVI----STVPVGR-----------------DLYV------------- 583
            |..::|...|:..:....:|    ...|:||                 :::|
Yeast   408 HVDFQENLEFIEKISAPNIILVHGEANPMGRLKSALLSNFASLKGTDNEVHVFNPRNCVEVDLEF 472

  Fly   584 --------TGEVPIRWYKYEGRASMLRTGFQPSISTFLATPKRAFAKFSADTEMFLSPVDENASK 640
                    .|.:....||.|.                :...:...||.....|.....:|..|.|
Yeast   473 QGVKVAKAVGNIVNEIYKEEN----------------VEIKEEIAAKIEPIKEENEDNLDSQAEK 521

  Fly   641 G---SEDKKD---------DDRESVV------------PTNHVTIISDTPE-------------- 667
            |   .|:.||         ||:...:            |....||:.:...
Yeast   522 GLVDEEEHKDIVVSGILVSDDKNFELDFLSLSDLREHHPDLSTTILRERQSVRVNCKKELIYWHI 586

  Fly   668 -------ECFQTDSKIPVKNEPLAPDTSPNS-----EIVAQLN-----AMESEIPYVE--IDIKN 713
                   |..|.|.:: ...||...:.|.::     :::.|:.     .:.:.:..||  .|:.|
Yeast   587 LQMFGEAEVLQDDDRV-TNQEPKVKEESKDNLTNTGKLILQIMGDIKLTIVNTLAVVEWTQDLMN 650

  Fly   714 ETIAPDAVLIPRVPTEDTFQSTDCNVIGVQKSQAVVVSRLTSDASDD 760
            :|:|...:.|               ::.|..:.|.|  :|:|.:.||
Yeast   651 DTVADSIIAI---------------LMNVDSAPASV--KLSSHSCDD 680

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snm1	NP_649548.1	SNM1A-1C-like_MBL-fold	252..408	CDD:293831	45/180 (25%)
		DRMBL	481..578	CDD:429512	23/142 (16%)
YSH1	NP_013379.1	CPSF3-like_MBL-fold	9..210	CDD:293850	44/176 (25%)
		YSH1	14..432	CDD:440849	81/413 (20%)
		CPSF73-100_C	533..777	CDD:463330	26/166 (16%)