Protein Alignment Snm1 and Dclre1a

DIOPT Version :10

• Sequence 1: NP_649548.1
• Gene: Snm1 / 40669
• FlyBaseID: FBgn0037338
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: XP_006527280.1
• Gene: Dclre1a / 55947
• MGIID: 1930042
• Length: 1047
• Species: Mus musculus
• Alignment Length: 585
• Identity: 188/585 - (32%)
• Similarity: 287/585 - (49%)
• Gaps: 75/585 - (12%)

  Fly    27 PTPTIENRTPDKKRAGRTRAASTTKKVRPKTEACPII------ASTAFKRSSKKTPLPGQMRIDS 85
            |..|.....|.:|..|:......|:.   :|...|..      |:.|.:.:.|::.:|    :|.
Mouse   484 PLLTRARSKPLEKEGGKCLPLHPTQS---QTRGSPRKGLGAPGANCACRNAQKRSSMP----LDK 541

  Fly    86 FFTSAVKNYKVKSSSSCRKVDPPLDKRKVSTKGRKRLFEESTTTSSAFTG---KLDAKPSEKRVQ 147
            ...::..:.|...|...:||...:|.........||  :|::...||..|   .....|::||
Mouse   542 PLGTSPSSPKCSPSQPSKKVMKQMDIGVFFGLPPKR--QETSLRESASEGPNVSPVVSPNQKR-- 602

  Fly   148 PSRRAKGKENASLSEV-----------HVIDLCSEDEQTIKRKPSAIAS----PCEKSSDVQATK 197
             .|..|.|..:|||::           |.:.|..|..|..:::.....|    ||::.|.
Mouse   603 -PRLCKRKAQSSLSDLEFDAKNLNESQHSVGLSGEKRQHRRKRHKTSNSPREGPCQRRSG----- 661

  Fly   198 FRTPETSMPEAKLSNSSLDLVEISPGPNKSPTNNFYRSSPAAITK-ESPLGKNSKKGTVRKQRKP 261
                      ..::|..|..|.:|.|      ..|.|.:.....: ...:.::|..|.||
Mouse   662 ----------HLMNNPELGPVILSKG------KAFVRRTRGRTQRGNMNISESSGAGEVR----- 705

  Fly   262 KPCPPYKVVEGTSFCVDGFQFGEIEGVTHYFLTHFHADHYIGLTKKFCHPLYVSPISARLVRTFI 326
            :.||.||.:.||.|.||.||:|||||.|.|||||||:|||.||:|.|..|:|.|.|:..|::..:
Mouse   706 RTCPFYKRIPGTGFTVDAFQYGEIEGCTAYFLTHFHSDHYAGLSKDFTRPVYCSEITGNLLKKKL 770

  Fly   327 KLDETHIHEIDVDQTLDVDGVQVTALEANHCPGALMFFFKLSSGECILHTGDFRASADMESLPIF 391
            ::.|.:|.::.:|....||.|:|..|:|||||||.|..|:|.:|..|||||||||...||...:.
Mouse   771 RVQEQYIRQLPMDTECVVDSVKVVLLDANHCPGATMILFQLPNGAVILHTGDFRADPSMERSRLA 835

  Fly   392 WNHSNIDLLYLDTTYMNKNYDFCHQSESVDRAVDLVRAFLEKNAAKRILIVCGSYVIGKEKIWLA 456
            ..  .:..|:|||||.:..|.|..|.|.:..|::  .||.......|.|:|||:|.|||||::||
Mouse   836 GR--KVHTLFLDTTYCSPEYTFPSQQEVIQFAIN--TAFEAVTLNPRALVVCGTYCIGKEKVFLA 896

  Fly   457 LAKEFTMRVWTESNRSTAVRCLNWPDLDSVLTEDRSGANLHVIAMGKISYPSLVDYFTEFEDQYD 521
            :|.....:|.....:...::|||.|::.|::|.|...:.:|::.|.:|::..|..:..:...:||
Mouse   897 IADVLGSKVGMSQEKYKTLQCLNIPEVSSLITTDMCDSLVHLLPMMQINFKGLQSHLKKCGGKYD 961

  Fly   522 MLLGIRPSGWEKNSK--------PSYGKRISTIGIEYSEHSSYKELERFVRFLKPKRVISTVPVG 578
            .:|..||:||..::.        |.....||..||.|||||||.|::|||::|||:::|.||.||
Mouse   962 QILAFRPTGWTHSNNITSTADIIPQTRGNISIYGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVG 1026

  Fly   579  578
            Mouse  1027  1026

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snm1	NP_649548.1	SNM1A-1C-like_MBL-fold	252..408	CDD:293831	75/155 (48%)
		DRMBL	481..578	CDD:429512	37/104 (36%)
Dclre1a	XP_006527280.1	metallo-hydrolase-like_MBL-fold	696..851	CDD:451500	76/161 (47%)
		DRMBL	921..1027	CDD:429512	39/106 (37%)