Protein Alignment Snm1 and ints-9

DIOPT Version :10

• Sequence 1: NP_649548.1
• Gene: Snm1 / 40669
• FlyBaseID: FBgn0037338
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: NP_504953.1
• Gene: ints-9 / 179142
• WormBaseID: WBGene00017608
• Length: 646
• Species: Caenorhabditis elegans
• Alignment Length: 646
• Identity: 126/646 - (19%)
• Similarity: 210/646 - (32%)
• Gaps: 204/646 - (31%)

  Fly   180 PSAIASPCEKSSDVQATKFRTPETSMPEAKLSNSSLDLVEISPGPNKSPTNNFYRSSPAAI---- 240
            |....||..|::.: |.||:.|.              |.|:.        |..|..||..|
 Worm    40 PHVYQSPRIKNAPI-AKKFQIPY--------------LKELG--------NRVYVESPPEIFHVS 81

  Fly   241 -------TKESPLGKNSKKGTVRKQRKPKPCPPYKVVEGTSFCVDG-------------FQFGEI 285
                   |.::.|..|                 |:...|..|..:|             :|:|::
 Worm    82 TDMLKMDTIDAILVSN-----------------YESFVGLPFYTEGSGFSGKIYVTEIAYQYGKL 129

  Fly   286 --EGVTHYFLTHFHA---------DHYIGLTKKFCHPLYVSPISARLVRTFIKLDETHIHE---- 335
              |.:.. |::....         :.:.|   ||.:|.:.:|:..|...|     .|.:|.
 Worm   130 LMEEMLE-FISRIEVLPSDKKWKREEFCG---KFPNPPFQNPVEWRPYYT-----TTDMHSCLAK 185

  Fly   336 ---IDVDQTLDVDGVQVTALEANHCPGALMFFFKLSSGECILHTGDFRASAD---MESLPI-FWN 393
               :..:||:|:..::||.:.:.|..|:..:..|..:.:....:....::.|   ||:.|: ..:
 Worm   186 VITLSFNQTIDLFRIKVTPVVSGHTYGSAYWTIKTENEQFAYLSASNPSATDVKLMETAPLRAVD 250

  Fly   394 HSNIDLL--YLDTTYMNKNY-------DFCHQSESVDRAVDLVRAFLEKNAAKRILIVCGSYVIG 449
            |..:..|  .:|||.....|       |...:..||...:..|....|...|...:|...:.:..
 Worm   251 HILVTSLSRLVDTTAKEMGYSLIKTITDVLKKHGSVLLPICPVGPIFEMIEAVSDIITTTNGIPL 315

  Fly   450 KEKIWL-------ALAKEFTMRVWTESNRSTAVRCLNWPDLDSVLTEDRSGANLHVIAMGKIS-Y 506
            ...|:.       |:|.......|...:|..||..   |:      |..|.:||  |..|::. |
 Worm   316 DTPIYFISPVAKSAIAMASISAEWMSESRQNAVYL---PE------EPYSHSNL--IKSGRVKIY 369

  Fly   507 PSLVDYFT-EFE---------------DQYDM--LLGIRPSGWEKNS--------------KPSY 539
            .||...|: ||:               |...|  :||..|    ||:              :|..
 Worm   370 DSLYGSFSKEFKTPCVIFASHASLRIGDAAHMVEVLGSDP----KNAVIVTDPDLPCEDVREPFR 430

  Fly   540 GKRISTIGIEYSEHSSYKELERFVRFLKPKRVISTVPVGRDLYVTGEVPIRWYK-----YE---- 595
            ...|..|.|.......:..|||.:...|||.|:.:....|.:....::.|.:.|     |:
 Worm   431 NLPIKFINIPMDFRMDFASLERLLADAKPKYVLCSSSYTRPMIRRPDMQINYEKVWPIEYDECVQ 495

  Fly   596 ------GRASMLRTGFQPSI---STFLATPKRAFA------KFSADTEMF-LSPVDENAS----- 639
                  .:..::.....|.:   ..|...|.:..|      ..||..:.| |.|.....:
 Worm   496 LSKLSRNKQKLVTVAVHPEVVKNLKFKQHPSKKLAVASIACHLSAYNDDFKLVPAKVKIARRKYG 560

  Fly   640 --------KGSEDKKDDDRESVVPTNHVTIISDTPEECFQTDSKIPVKNEPLAPDTSPNSE 692
                    |...||..|.:|...|       .:|..|..:.::||.|||:......|.|::
 Worm   561 RITLAKVLKALRDKNWDAKEVEKP-------DETVLEIDELEAKITVKNDGTGTKISSNNQ 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snm1	NP_649548.1	SNM1A-1C-like_MBL-fold	252..408	CDD:293831	34/192 (18%)
		DRMBL	481..578	CDD:429512	31/129 (24%)
ints-9	NP_504953.1	metallo-hydrolase-like_MBL-fold	1..256	CDD:451500	48/264 (18%)
		Beta-Casp	298..416	CDD:214983	30/132 (23%)