Protein Alignment Snm1 and CPSF2

DIOPT Version :10

• Sequence 1: NP_649548.1
• Gene: Snm1 / 40669
• FlyBaseID: FBgn0037338
• Length: 763
• Species: Drosophila melanogaster
• Sequence 2: XP_061504328.1
• Gene: CPSF2 / 1273485
• VectorBaseID: AGAMI1_004813
• Length: 790
• Species: Anopheles gambiae
• Alignment Length: 567
• Identity: 107/567 - (18%)
• Similarity: 178/567 - (31%)
• Gaps: 199/567 - (35%)

  Fly   280 FQFGEIEGVTHYFLT------------HFHADHY----IGLTKKFCHPLYVSPISARLVRTFIK- 327
            |..|.|:.:..|..|            |..|..|    :||.   | |:|.:....::.:.|:.
Mosquito    40 FDQGFIKEIKKYVHTIDAVLLSYPDGSHLGALPYLVGKLGLN---C-PIYATIPVYKMGQMFMYD 100

  Fly   328 --LDETHIHEIDVDQTLDVD----------------------GVQVTALEANHCPGALMFFFKLS 368
              :...::|:.|:....|||                      |:.:|.|.|.|..|..::.....
Mosquito   101 MFMSHYNMHDFDLFSLDDVDAAFDKIVQLKYNQSVAMKGKGYGITITPLPAGHLIGGTIWKIVKV 165

  Fly   369 SGECILHTGDFR-------ASADMESLPIFWNHSNIDLLYLDTTYMNKNYDFCHQSESVDRAVDL 426
            ..|.|::..||.       ...::|.|      ....||..|.  .|..|....:....::.:..
Mosquito   166 GEEDIVYATDFNHKKERHLNGCELEKL------QRPSLLITDA--YNARYQQARRRARDEKFMTN 222

  Fly   427 VRAFLEKNAAKRILIVCGSYVIG----KEKIW-----------LALAKEFTMRVWTESNRSTAVR 476
            :...|..|....:.:.....|:.    .:::|           |||....:..| .|..:|.
Mosquito   223 ILQTLRNNGNVLVTVDTAGRVLELAHMLDQLWKNKESGLMAYSLALLNNQSYNV-VEFAKSQ--- 283

  Fly   477 CLNWPDLDSVLTEDRSGAN-----------LHVIA-MGKISYPSLV-DYFTEFEDQYDMLLGIRP 528
             :.|  :...|.:...||.           .|.:| :.|:..|.:| ....:.|..:...|.|:
Mosquito   284 -IEW--MSDKLMKSFEGARNNPFTFKHLRLCHTMADLAKVPSPKVVLASSPDLESGFSRELFIQ- 344

  Fly   529 SGWEKN--------SKPSYG---------------------KRISTIGIEYSEHSSYKELERFVR 564
              |..|        |:.|.|                     :|:...|.|..|:.. .|.|:..|
Mosquito   345 --WAPNASNSIIITSRSSPGTLARDLIENGGNGRKIEMDIRRRVELEGAELEEYMR-TEGEKLNR 406

  Fly   565 FLKPKRVISTVPVGRDL--------------YVTG--EVPIRWYKYEGRASMLRTGFQPSISTFL 613
            .:|.          |||              .:||  ::.:|   .|||:   .||       |.
Mosquito   407 SIKK----------RDLDESSSDSDDELEMNVITGKHDIVVR---PEGRS---HTG-------FF 448

  Fly   614 ATPKRAFAKFSADTEMF------------------LSPV----DENASKGSEDKKDDDRESVVPT 656
            .:.|:.:|.|....|..                  |.|.    |:|...|....:|..:|.   .
Mosquito   449 KSSKKNYAMFPFHEEKIKYDEYGEIIQPDDYRMVDLGPETNGGDDNKENGGIKTEDIKKEK---E 510

  Fly   657 NHVTIISDTPEECFQTDSKIPVKNEPLAPDTSPNSE------IVAQL 697
            :.||:: |.|.:|.|:...|.|..:....|....|:      |::||
Mosquito   511 DEVTVL-DKPTKCVQSRKPIEVNAQVQFIDFEGRSDGESLLKILSQL 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snm1	NP_649548.1	SNM1A-1C-like_MBL-fold	252..408	CDD:293831	34/175 (19%)
		DRMBL	481..578	CDD:429512	24/138 (17%)
CPSF2	XP_061504328.1	None