DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mia and TAFII59

DIOPT Version :9

Sequence 1:	NP_001138010.1	Gene:	mia / 40667	FlyBaseID:	FBgn0014342	Length:	589	Species:	Drosophila melanogaster
Sequence 2:	NP_001030969.1	Gene:	TAFII59 / 839370	AraportID:	AT1G04950	Length:	549	Species:	Arabidopsis thaliana

Alignment Length:	561	Identity:	140/561 - (24%)
Similarity:	243/561 - (43%)	Gaps:	105/561 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 SLSPRSLSAIFFHSTGL-HLDDGVAQWLSINVKEDITNLLNEAGKYMRRIRDRRLQLSHIQHAVR 93
            |:.|:....:...|.|: :|....|..|:.:|:..:..::.||.|.||..:...|..|.:..|:.
plant     2 SIVPKETVEVIAQSIGITNLLPEAALMLAPDVEYRVREIMQEAIKCMRHSKRTTLTASDVDGALN 66

  Fly    94 M----------------------HDDLCYDIFFRLVHCDDCKMPPSQKVLKTVREA--VTAEKKD 134
            :                      |.||.|        .||.::.     .|.|.||  ..|....
plant    67 LRNVEPIYGFASGGPFRFRKAIGHRDLFY--------TDDREVD-----FKDVIEAPLPKAPLDT 118

  Fly   135 ELLVSY--PESVQESVPEPVPETSLEPP-----------PMHTGWLKVEQVLLKPSKRYPLSMEQ 186
            |::..:  .|.||.::||..|...:..|           |:....|.|:.|         ||.|.
plant   119 EIVCHWLAIEGVQPAIPENAPLEVIRAPAETKIHEQKDGPLIDVRLPVKHV---------LSREL 174

  Fly   187 QNFFELVTEACVGDLESRRVL---ALKAISTDPSLEELLPRLTKFIADAVAINVAQQNLPLLLYL 248
            |.:|:.:.|..:.  :|...|   ||.::::|..|..|:|..|.||||.|:..:  .:..||..|
plant   175 QLYFQKIAELAMS--KSNPPLYKEALVSLASDSGLHPLVPYFTNFIADEVSNGL--NDFRLLFNL 235

  Fly   249 MRMVRALLGNQRFSLLQYLHLLLPAVLSCLLAKQVCASPNSEDHWALREYSGNIMAHIVRQFDAA 313
            |.:||:||.|....:..|||.|:|:|::||::::: .:..:::||.||:::.|:::.|.:::...
plant   236 MHIVRSLLQNPHIHIEPYLHQLMPSVVTCLVSRKL-GNRFADNHWELRDFAANLVSLICKRYGTV 299

  Fly   314 DNGILPRVIGVYNKALL--KKPLTTVFGAVIGLGKMGNHAVRACILPQLK-YLSEHIDSHMAASN 375
            ...:..|:......|||  ||.||..:||:.||..:|:..||..||..|: ||| .::..:.|..
plant   300 YITLQSRLTRTLVNALLDPKKALTQHYGAIQGLAALGHTVVRLLILSNLEPYLS-LLEPELNAEK 363

  Fly   376 DSPSSSVDR---------QAVKYIRHRLMKMCSPVLMGIHQPPDLPEEFMERYGSLGTLMSDGVT 431
            ......:..         :|.....|..:|:..|:       |.....|:.:....|.::|..
plant   364 QKNQMKIYEAWRVYGALLRAAGLCIHGRLKIFPPL-------PSPSPSFLHKGKGKGKIISTD-- 419

  Fly   432 VMRTKKQAVAAAKAEAELKLKNMAT----EHLNSRGK-GSRSVGSNDLVSGTQLPKNGIRPTS-- 489
               ..|:.::...:|.:...|.:.|    :.::|:.: ||..:..::.|.....|:|.::|:|
plant   420 ---PHKRKLSVDSSENQSPQKRLITMDGPDGVHSQDQSGSAPMQVDNPVENDNPPQNSVQPSSSE 481

  Fly   490 QAPKSVYSISVNGQTVKISTPNLCNTML----QHQKKDLFS 526
            ||..:..|.|.||: ||.|..:...||.    |..|.||.|
plant   482 QASDANESESRNGK-VKESGRSRAITMKAILDQIWKDDLDS 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mia	NP_001138010.1	TAF6	33..352	CDD:173968	94/361 (26%)
mia	NP_001138010.1	TAF6	40..422	CDD:227426	108/434 (25%)
TAFII59	NP_001030969.1	TAF6	1..383	CDD:227426	104/408 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5095
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D384329at2759
OrthoFinder	1	1.000	-	-		FOG0003125
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10221
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	8	7.880