Protein Alignment mia and Taf6

DIOPT Version :9

• Sequence 1: NP_001138010.1
• Gene: mia / 40667
• FlyBaseID: FBgn0014342
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: XP_011239238.1
• Gene: Taf6 / 21343
• MGIID: 109129
• Length: 689
• Species: Mus musculus
• Alignment Length: 557
• Identity: 145/557 - (26%)
• Similarity: 251/557 - (45%)
• Gaps: 130/557 - (23%)

  Fly    19 MPDKDKSFRRHSLSPRSLSAIFFHSTGL-HLDDGVAQWLSINVKEDITNLLNEAGKYMRRIRDRR 82
            |.::.|....:::.|.....:...|.|: .:.:...|.|:..|...|..:..:|.|:|...:.::
Mouse     1 MAEEKKLKLSNTVLPSESMKVVAESMGIAQIQEETCQLLTDEVSYRIKEIAQDALKFMHMGKRQK 65

  Fly    83 LQLSHIQHAVRMHD-DLCYDIFFRLVHCDDCKMPPSQKVLKTVREAVTAEKKD-EL--LVSYP-- 141
            |..|.|.:|:::.: :..|..     |..:  ..|.:......||....|:|: :|  :::.|
Mouse    66 LTTSDIDYALKLKNVEPLYGF-----HAQE--FIPFRFASGGGRELYFYEEKEVDLSDIINTPLP 123

  Fly   142 ---------------ESVQESVPE---PVPE-----TSLEP------------------------ 159
                           |..|.::||   |.|:     .:.||
Mouse   124 RVPLDVCLKAHWLSIEGCQPAIPENPPPAPKEQQKAEATEPLKSAKPGQEEDGPLKGKGQGAAAA 188

  Fly   160 ---------PPMHTGWLKVEQVLLKPSKRYPLSMEQQNFFELVTEACVGDLESRRVLALKAISTD 215
                     ||:    |:.....|||...:.||:|||.:::.:||||||..|::|..||::|:||
Mouse   189 DGKGKEKKAPPL----LEGAPFRLKPRSIHELSVEQQLYYKEITEACVGSCEAKRAEALQSIATD 249

  Fly   216 PSLEELLPRLTKFIADAVAINVAQQNLPLLLYL---MRMVRALLGNQRF------SL----LQYL 267
            |.|.::|||.:.||::.|  ....::.|::...   |..||...||...      ||    |..:
Mouse   250 PGLYQMLPRFSTFISEGV--RELGKDRPMMRLQGRGMTRVRGPSGNLTTGGLVSDSLTGPGLSQV 312

  Fly   268 HLLLPAVLSCLLAKQVCASPNSEDHWALREYSGNIMAHIVRQFDAADNGILPRVIGVYNKALL-- 330
            |.|:|||::|::::|:|..|:.::|||||:::..::|.|.:.|....|.|..|:...:.|:.:
Mouse   313 HELIPAVMTCIVSRQLCLRPDVDNHWALRDFAARLVAQICKHFSTTTNNIQSRITKTFTKSWVDE 377

  Fly   331 KKPLTTVFGAVIGLGKMGNHAVRACILPQLKYLSEHIDSHMAASNDSP-SSSVDRQAVKYIRHRL 394
            |.|.||.:|::.||.::|:..::..|||:|:...|.|.|.:    |.| .|::||....:::..|
Mouse   378 KTPWTTRYGSIAGLAELGHDVIKTLILPRLQQEGERIRSVL----DGPVLSNIDRIGADHVQSLL 438

  Fly   395 MKMCSPVLMGIHQPPDLPEEFMERYGSLGTLMSDGVTVMRTKKQAVAAAKAEAELKLKNMATEHL 459
            :|.|:|||..:..|||..:.:...:||||.|:...|    .|.:|.||.:|:.
Mouse   439 LKHCAPVLAKLRPPPDNQDAYRGEFGSLGPLLCSHV----VKARAQAALQAQQ------------ 487

  Fly   460 NSRGKGSRSVGSNDLVSGTQLPKNGIRPT---SQAPK 493
                           |:.|.|.....|||   ||||:
Mouse   488 ---------------VNRTTLTITQPRPTLTLSQAPQ 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mia	NP_001138010.1	TAF6	33..352	CDD:173968	101/396 (26%)
		TAF6	40..422	CDD:227426	122/460 (27%)
Taf6	XP_011239238.1	TAF	11..76	CDD:281032	14/64 (22%)
		TAF6C	214..441	CDD:381749	77/232 (33%)
		HEAT repeat	218..249	CDD:381749	14/30 (47%)
		HEAT repeat	256..288	CDD:381749	8/33 (24%)
		HEAT repeat	312..355	CDD:381749	16/42 (38%)
		HEAT repeat	362..394	CDD:381749	10/31 (32%)
		HEAT repeat	396..440	CDD:381749	13/47 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5095
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003125
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10221
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.870