Protein Alignment mia and taf-6.2

DIOPT Version :9

• Sequence 1: NP_001138010.1
• Gene: mia / 40667
• FlyBaseID: FBgn0014342
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: NP_500397.2
• Gene: taf-6.2 / 177129
• WormBaseID: WBGene00021363
• Length: 835
• Species: Caenorhabditis elegans
• Alignment Length: 679
• Identity: 126/679 - (18%)
• Similarity: 233/679 - (34%)
• Gaps: 187/679 - (27%)

  Fly     5 ENKNATKMKTS-QNEMPDKDKSFRRHSLSPRSLSAIFFHSTGLHLDDGVAQWLSINVKEDITNLL 68
            |.::..::|.| ....|..|....|   ||..|.:         |....|..:....:..:..::
 Worm    78 EKQDPAEIKVSAPRPTPSLDDVIER---SPELLGS---------LTTAAANSIGACTRLVLRTII 130

  Fly    69 NEAGKYMRRIRDRRLQLSHIQHAVRMHDDLCYDIFFRLVHCD---DCKM----PPSQKVL---KT 123
            ..|.|...|...:||..|.:            ||...:...|   .|.:    |.|.::.   |.
 Worm   131 QNAKKSASRENRKRLVPSDV------------DIACGIAQIDYNLTCPLLRPTPSSDRMYWGRKL 183

  Fly   124 VREAVTAEKKDELLVSYP---------------ESVQESVPEPV---------PETSLEPPPMHT 164
            .:|..|.:...:.:||:.               :.:|..:||.|         .|...|....|
 Worm   184 TKEHYTIDANSKEMVSHERFCDSIMIKDHWLVVDGIQPCLPENVIPSEVKRRFQEQQHETQRAH- 247

  Fly   165 GW----LKVEQVLLKPSKRYPLSMEQQNFFELVTEACVGDLESRRVLALKAISTDPSLEELLPRL 225
            |:    :|.|.:..|.......|||.|..:..:|:........:|...|:.|.||..::.|..|.
 Worm   248 GFGVPGIKREPMPEKRMSTQTFSMEHQVLYSEITKILTSGSSLQRQKVLETIETDTGIQFLAGRF 312

  Fly   226 TKFIADAVAINVAQQNLPLLLYLMRMVRALLGNQRFSLLQYLHLLLPAVLSCLLAKQVC------ 284
            ...||:...:::..:|:..|..|:::..:|:.|....|.:||::|:|:::||:::|.:.
 Worm   313 VILIAEGTRLHIGTRNIRGLANLLKLTWSLMKNPNIRLEKYLYVLVPSLISCVVSKNMVPILDVS 377

  Fly   285 -----ASPNS-----------------------EDHWALREYSGNIMAHIVRQFDAADNGILPRV 321
                 |.|.:                       |..:.|||.||.::|.:..|:...:..:  |:
 Worm   378 RVGLKAKPTTVTPLGATPPELTADDRERIIRDLEFEFKLREASGKLLAELSSQYQNLNLNV--RI 440

  Fly   322 IGVYNKALL-KKPLTTVFGAVIGLGKMGNHAVRACILPQLKYLSEHIDSHMAASNDSPSSS---- 381
            |......|. .:....::|.:..|...||..:.:.:||:   :.:...|..|:.::.|...
 Worm   441 IQTLRGVLSGNQDPAAIYGVLCTLFAFGNLTINSVVLPK---MHDIYCSLQASRSEIPQVKPTMT 502

  Fly   382 ------VDRQA--VKYIRHRLMKMCSPVLMGIHQPPDLPEEFMER-----------YGSLGTLMS 427
                  |:.:|  ::.:::|.:::...::..       .|.|.:|           |...|.|..
 Worm   503 KLRKIVVETEASRMEIVQNRTIELVMKIIFE-------NEIFNDRKSADRDVYVNLYAEFGALFY 560

  Fly   428 DGVTVMRTKKQAVAAAK-AEAELKLKNMA-TEHLNSRGKGSRSVGSNDLVSGTQLPKNGIRPTSQ 490
            |.........|.....| ....|.||..| .|.|..|.:..||.
 Worm   561 DYALNTEMVDQYTGHLKITRPSLLLKQEAYLEELERRRRIRRST--------------------- 604

  Fly   491 APKSVYSISVNGQTVKISTPNLCNTMLQHQKKDLFSKPSDFVVPQLVVNQFKNGLIPSNSQRSSS 555
                            .:|....:...|||::.|.:.|       ::.....:.|:..:::..|.
 Worm   605 ----------------TTTTTTSSHHHQHQQQQLHNHP-------MIDEAMLDNLLDDSNRPWSK 646

  Fly   556 PARNV--IHLKPNNDHPS-----KMALFL 577
            ||..:  ..|:|:.|...     |..|||
 Worm   647 PAAQLDEQQLEPHLDREKETFFRKPKLFL 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mia	NP_001138010.1	TAF6	33..352	CDD:173968	76/391 (19%)
		TAF6	40..422	CDD:227426	86/477 (18%)
taf-6.2	NP_500397.2	TAF6C	270..496	CDD:381749	48/230 (21%)
		HEAT repeat	271..302	CDD:381749	7/30 (23%)
		HEAT repeat	309..344	CDD:381749	7/34 (21%)
		HEAT repeat	354..431	CDD:381749	15/76 (20%)
		HEAT repeat	436..467	CDD:381749	5/32 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164601
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5095
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D384329at2759
OrthoFinder	1	1.000	-	-		FOG0003125
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10221
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.940