Protein Alignment mia and LOC1274098

DIOPT Version :10

• Sequence 1: NP_649547.3
• Gene: mia / 40667
• FlyBaseID: FBgn0014342
• Length: 589
• Species: Drosophila melanogaster
• Sequence 2: XP_313173.6
• Gene: LOC1274098 / 1274098
• VectorBaseID: AGAMI1_000476
• Length: 683
• Species: Anopheles gambiae
• Alignment Length: 631
• Identity: 186/631 - (29%)
• Similarity: 291/631 - (46%)
• Gaps: 121/631 - (19%)

  Fly    19 MPDKDKSFRRHSLSPRSLSAIFFHSTGL-HLDDGVAQWLSINVKEDITNLLNEAGKYMRRIRDRR 82
            |.|:||:....:||..|:..| ..|.|: .|.|..|:.|:.:|...:..::.:|.|:|...:..:
Mosquito     1 MGDRDKTMYGSTLSLESIKVI-AESIGVGSLPDDAAKELADDVSYKLKQIVQDAVKFMHHSKRMK 64

  Fly    83 LQLSHIQHAVRMHD-DLCYDIFFRLVHCDDCKMPPSQKVLKTVREAVTAEKKDELLVSYPESVQE 146
            |.::.:.|::::.: :..|....|       ...|.:......||....|:|:   |...|.||.
Mosquito    65 LSIADVDHSLKVRNIEPQYGFVAR-------DFIPFRFASGGGRELHFIEEKE---VDLTEMVQG 119

  Fly   147 SVP----EP---------------VPETSLEPPPMH-----------------------TGWLKV 169
            ..|    ||               |||   .|||:.                       ||...:
Mosquito   120 QTPKIPLEPSLRAHWLAVEGVQPTVPE---NPPPLSKDVQALDSVNPAHKLDKTNQKDTTGKPTI 181

  Fly   170 --------EQVLLKPSKRYPLSMEQQNFFELVTEACVGDLESRRVLALKAISTDPSLEELLPRLT 226
                    |.|.:|...::.||:|||.:::.:||||||..|:||..||.::|:||.|.|:|||:.
Mosquito   182 NKHKLKNSETVQVKQLAQHELSVEQQLYYKEITEACVGSDEARRAEALTSLSSDPGLHEMLPRMC 246

  Fly   227 KFIADAVAINVAQQNLPLLLYLMRMVRALLGNQRFSLLQYLHLLLPAVLSCLLAKQVCASPNSED 291
            .|||:.|.:||.|.||.||:||||||||||.|....|.:|||.|:|.|.:|::::|:|..|..::
Mosquito   247 TFIAEGVKVNVVQNNLALLIYLMRMVRALLDNPALYLEKYLHELIPCVSTCIVSRQLCMRPELDN 311

  Fly   292 HWALREYSGNIMAHIVRQFDAADNGILPRVIGVYNKALL--KKPLTTVFGAVIGLGKMGNHAVRA 354
            |||||:::..:||.|.:.|:.:.|.:..||..:::.||.  |.||::::||:.||.::|....:.
Mosquito   312 HWALRDFAARLMAQICKTFNTSTNNLQTRVTRLFSAALQNDKTPLSSMYGALQGLSELGTEVTKV 376

  Fly   355 CILPQLKYLSEHIDSHMAASNDSPSSSVDRQAVKYIRHRLMKMCSPVLMGIHQPPDLPEEFMERY 419
            .|:|:||::||.::. :.....|..|:.|:.|..:||..|.|...|:|..:..||||.||:...|
Mosquito   377 FIIPRLKFISERVEP-LLQGITSNISNTDKIAAGHIRAILQKGVPPILKTLRNPPDLVEEYKRDY 440

  Fly   420 GSLGTLMSDGVTVMRTKKQAVAAAKA---EAELKLKNMATEHLNSRGKGSRSVGSNDLVSGTQLP 481
            |.||..:...|...|:...:..|..|   .|.....:.||....|....|    ||.:|. |..|
Mosquito   441 GCLGQTLHQAVVKARSASPSSGAGGAGGSSASSTTPSTATSITVSTSNNS----SNTVVL-TATP 500

  Fly   482 KNGIRPTSQAPKSVYSISVNGQTVKISTPN--------LCNTMLQHQKKDLFSKPSD---FVVPQ 535
            .   ||  |.|:::.:......|..|..|.        :.||..|      .|:|..   .:|||
Mosquito   501 S---RP--QTPQAISAAKTIAATASIQRPGTAAGGGVAVLNTGSQ------ASQPPQQKFVIVPQ 554

  Fly   536 LVVNQFKNGLIPSNSQ---------------RSSSPARNVIHLKPN 566
                   ....||.||               ..::.|...:.::||
Mosquito   555 -------RAQTPSPSQDDFVGPIIQRQGSVSGGAAAATTTVQIQPN 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mia	NP_649547.3	HFD_SF	<47..94	CDD:480273	10/46 (22%)
		TAF6C	181..397	CDD:381749	92/217 (42%)
		HEAT repeat	184..215	CDD:381749	15/30 (50%)
		HEAT repeat	222..257	CDD:381749	23/34 (68%)
		HEAT repeat	267..310	CDD:381749	17/42 (40%)
		HEAT repeat	317..347	CDD:381749	11/31 (35%)
		HEAT repeat	349..396	CDD:381749	13/46 (28%)
LOC1274098	XP_313173.6	None