Protein Alignment Nmdar1 and grik5

DIOPT Version :9

• Sequence 1: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Sequence 2: NP_001315085.1
• Gene: grik5 / 798791
• ZFINID: ZDB-GENE-070821-6
• Length: 1067
• Species: Danio rerio
• Alignment Length: 1059
• Identity: 265/1059 - (25%)
• Similarity: 427/1059 - (40%)
• Gaps: 264/1059 - (24%)

  Fly    40 NIGGVLSNSDSEEHFSTTIKHLNFDQQYVPRKVTYYDKTIRMDKNPIKTVFNVCDKLIENRVYAV 104
            ||..|:.| .:.......|..|..|.||                   :|...:|..|.:..|..:
Zfish    63 NINSVMEN-PARARVEVDIFELQKDSQY-------------------ETTDTMCQILPKGVVSVI 107

  Fly   105 VVSHEQTSGDLSPAAVSYTSGFYSIPVIGISSRDAAFSDKNIHVSFLR--TVPPYYHQADVWL-- 165
            ..:....||.:    ||:..|...||.:.|...:..      .:.:||  :|..|....|:.|
Zfish   108 GPASSPASGSI----VSHICGEKEIPHVKIGPEETP------RLPYLRFASVTLYPSNEDLSLAI 162

  Fly   166 -EMLSHFAYTKV--------IIIHSSDTDGRAILGRFQTTSQTYYDDVDVRATVELIVEFEPKLE 221
             .:|..|:|...        .::...:...|.::.| :|.|....||           ..:|
Zfish   163 GSILRSFSYPSASLVCAKAECLLRLEELIRRFLISR-ETLSIRMLDD-----------NLDP--- 212

  Fly   222 SFTEHLIDMKTAQSRVYLMYASTEDAQVIFRDAGEYNMTGEGHVWIVT--------------EQ- 271
              |..|.:::..:....::.|:...:.:|.:.|.|..||...:.:|:|              ||
Zfish   213 --TPLLKEIRDDKIATIIIDANASISYLILKKASELGMTSAFYKYILTTMDFPLLWLDDIVDEQS 275

  Fly   272 -----ALFSNNTP---DGVLGLQLEHAHS-----------DKGHIRDSVYVLASAIKEMISNETI 317
                 ::|:...|   :.:..|.|.....           ....:.|:|:|:.||::|:..::.|
Zfish   276 NIVGFSMFNTTHPFYLEFIRSLNLSWREGCDINPYPGPALSSALLFDAVHVVVSAVQELNRSQEI 340

  Fly   318 AEAPKDCGDSAVNWESGKRLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINIREQQKKHVVGK 382
            ...|..|....: |:.|..|..||:.....|.||:|.|:..|.|  ..|.:..:.:.:..|....
Zfish   341 GVKPLSCTSPQI-WQHGTSLMNYLRMVEYDGLTGRVEFNSKGQR--TNYTLHILEKHRGGHKEIG 402

  Fly   383 FSYDSMRAKMR---MRINDSEIIWPGKQRRKPEGIMIPTHLRLLTIEEKPFVYVRRMGDDEFRCE 444
            ..|.:....|.   :.||.||             .:....|.:.||.|.|:| :|::...||  |
Zfish   403 IWYSNNTLLMNSTSLDINVSE-------------TLANKSLIITTILENPYV-MRKINYQEF--E 451

  Fly   445 PDERPCPLFNNSDATANEFCCRGYCIDLLIELSKRINFTYDLALSPDGQFGHYILRNNTGAMTLR 509
            .:|:                ..|:|:|:|.|||..:.|||.:.|..||.:         ||....
Zfish   452 GNEQ----------------YEGFCVDMLRELSDILKFTYRIKLVDDGLY---------GAPEPN 491

  Fly   510 KEWTGLIGELVNERADMIVAPLTINPERAEYIEFSKPFKYQGITIL-----EKKPSRSSTLVSFL 569
            ..|||::|||:|.:||:.||..||..||.:.|:|||||...||:||     .:||.    ..|||
Zfish   492 GSWTGMVGELINRKADLAVAAFTITSEREKVIDFSKPFMTLGISILYRVHIGRKPG----YFSFL 552

  Fly   570 QPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSHSDSNEEKAL-----NLSSAVWFAWGVL 629
            .|||..:|:.::::...|:.||:|..|.||:..:. .|....|.:.|     .|.:::||..|..
Zfish   553 DPFSPAVWLFMLLAYLAVSCVLFLSARLSPYEWYN-PHPCLRERRDLLENQYTLGNSLWFPVGGF 616

  Fly   630 LNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTKLSGINDARLRNTMENL 694
            :..| .|..||:.|.|.:..||..|.:||::||||||||||.::|.:..:...:|..   ...|:
Zfish   617 MQQG-SEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESPDDLA---DQTNI 677

  Fly   695 TCATVKGSSVDMYFRRQVELSNMYRTMEAN-NY----------ATAEQAIQDVKKGKLMAFIWDS 748
            ...|:.|.|...:|     :::.|:|.:.. ||          .:.|:.|..|...| .||:.:|
Zfish   678 QYGTIHGGSTMTFF-----MNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVVNSK-YAFLLES 736

  Fly   749 SRLEYEASKDCELVTAGELFGRSGYGIGLQKGSPWTDAVTLAILEFHESGFMEKLDKQWIFHGHV 813
            :..||..|.:|.|...|.|....|||||:..|||:.|.::||:|:..|:..:|.|.::|...|
Zfish   737 TMNEYHRSLNCNLTQIGGLLDTKGYGIGMPLGSPFRDELSLAVLQLQENNRLEILKRRWWEGG-- 799

  Fly   814 QQNCELFEKTPNT-------LGLKNMAGVFILVGVGIAGGVGLIIIEVIYKKHQVKKQKRLDIAR 871
                    |.|..       ||::|:.|:|:::..|:...|.:.::|.::.            .|
Zfish   800 --------KCPKEEDHRAKGLGMENIGGIFVVLICGLIIAVFVAVMEFVWS------------TR 844

  Fly   872 HAADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGTISL----------AVDKRRYPRLGQR- 925
            .:|:    |.|.|     .|:..|||       |:..|:|:          ||..::..||.:|
Zfish   845 RSAE----TDEVR-----PLSCDRQY-------HSHTTVSVCQEMLTEFRNAVSCKKSSRLRRRR 893

  Fly   926 --------LGPERAWPGDAADVLRIRRPYELGN---------------PGQSPKVMAANQPG--- 964
                    ..|.|...| |...||:.|...|.|               ||..|..|.   ||
Zfish   894 PLSSSLALRHPTRITLG-APRPLRLVREMRLSNGKLYSGTGPLTGGSGPGGGPTDMG---PGPQR 954

  Fly   965 -MPMPMLGKTRPQQSVLPP 982
             :..|:...:.|..::.||
Zfish   955 LLEDPLGANSTPAVALGPP 973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	12..405	CDD:107374	82/414 (20%)
		ANF_receptor	58..371	CDD:279440	71/359 (20%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	137/421 (33%)
		HisJ	451..>558	CDD:223904	40/111 (36%)
		Periplasmic_Binding_Protein_Type_2	<516..651	CDD:304360	51/144 (35%)
		Lig_chan	575..838	CDD:278489	85/285 (30%)
		CaM_bdg_C0	854..882	CDD:287524	3/27 (11%)
grik5	NP_001315085.1	PBP1_iGluR_Kainate_KA1_2	38..412	CDD:107389	77/398 (19%)
		ANF_receptor	55..392	CDD:279440	75/378 (20%)
		Periplasmic_Binding_Protein_Type_1	<313..383	CDD:299141	20/70 (29%)
		Periplasmic_Binding_Protein_Type_2	427..797	CDD:304360	136/412 (33%)
		Lig_chan	558..828	CDD:278489	85/290 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910