Protein Alignment Nmdar1 and KaiR1D

DIOPT Version :10

• Sequence 1: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Sequence 2: XP_061498559.1
• Gene: KaiR1D / 4576020
• VectorBaseID: AGAMI1_006981
• Length: 930
• Species: Anopheles gambiae
• Alignment Length: 1003
• Identity: 248/1003 - (24%)
• Similarity: 425/1003 - (42%)
• Gaps: 195/1003 - (19%)

  Fly    15 LAIVLLVAPIDAAQRHTASDNPSTYNIGGVLSNSDSEEH--FSTTIKHLNFDQQYVPR------- 70
            |..:||..|..|...      |....|||:....|..:.  |...::.:|.|:..:||
Mosquito    15 LLALLLHGPAPARAL------PDAIRIGGLFHPDDDHQEIAFRYAVEKINSDRTILPRSKLLAQI 73

  Fly    71 -KVTYYDKTIRMDKNPIKTVFNVCDKLIENRVYAV-------VVSHEQTSGDLSPAAVSYTSGFY 127
             :::..|..:...:        || .|:...|.|:       ..||.|:..|........|...|
Mosquito    74 ERISPQDSFLASKR--------VC-HLLGVGVAAIFGPQSSHTASHVQSICDTMEIPHLETRWDY 129

  Fly   128 SIPVIGISSRDAAFSDKNIHVSFLRTVPPYYHQADVWLEMLSHFAYTKVIIIHSSD--------- 183
            .:      .|::...:...|.|.|         :..::::::.:.:....||:.::
Mosquito   130 RL------RRESCLVNLYPHPSTL---------SKAYVDLVAAWGWKSFTIIYETNEGLVRMQEL 179

  Fly   184 --TDGRAILGRFQTTSQTYYDDVDVRATVELI---VEFEPKLESFTEHLID-MKTAQS----RVY 238
              ..|   |..:..|.:...|..|.|..::.|   .|....|:..||.:.: :|.||.    ..|
Mosquito   180 LKAHG---LSDYPITVRQLSDSGDYRPLLKQIKNSAESHIVLDCSTERIYEVLKQAQQIGMMSDY 241

  Fly   239 LMYASTE-DAQVIFRDAGEY---NMTG------EG-------HVWIVTEQALFSN---NTPDGVL 283
            ..|..|. |...|..|..:|   |:|.      |.       |.|.:.|..|...   .|.:.|.
Mosquito   242 HSYLITSLDLHTINLDEFKYGGTNITAFRLVDPENPEVAQAIHNWTIGEARLGKKVDFKTAENVT 306

  Fly   284 GLQLEHAHSDKGHIRDSVYVLASAIKEMISNETIAEAPKDCGDSAVNWESGKRLFQYLKSRNITG 348
            .::.|.|     .:.|:|::.|.|:.::.:::.|...|..| |:...|..|..|..|:|...:.|
Mosquito   307 VIKAETA-----LMYDAVHLFAKALHDLDTSQQIDIHPLSC-DTQDTWPHGYSLINYMKIVEMRG 365

  Fly   349 ETGQVAFDDNGDRIYAGYDVINIREQQKKHVVGKFSYDSMRAKMRMRINDSEIIWPGKQRRKPEG 413
            .|..:.||..|.|.....|::.:..|..:. .|.::..|       .:|.:...  |:|:::...
Mosquito   366 LTDVIKFDHQGFRSDFVLDIVELGPQGLRK-SGTWNSTS-------GVNFTRTY--GEQQKEIVE 420

  Fly   414 IMIPTHLRLLTIEEKPFVYVRRMGDDEFRCEPDERPCPLFNNSDATANEFCCRGYCIDLLIELSK 478
            |:....|.:.||...|:            |...:....|..||     :|  .||.|||:.|:||
Mosquito   421 ILQNKTLIVTTILSAPY------------CMRKDSAEKLTGNS-----QF--EGYAIDLIHEISK 466

  Fly   479 RINFTYDLALSPDGQFGHYILRNNTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERAEYIEF 543
            .:.|.|.:.|:|||::|.:  ...||      ||.|:|.||:.:|||:.:|.|||..:|.:.::|
Mosquito   467 ILGFNYTIRLAPDGRYGSH--NKETG------EWDGMIKELLEQRADLAIADLTITFDREQVVDF 523

  Fly   544 SKPFKYQGITILEKKP-SRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSH 607
            :.||...||::|.:|| .:...|.|||.|.|..:||.:..:...|:::|::|.||:|:.....:.
Mosquito   524 TMPFMNLGISVLYRKPVKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILARFTPYEWPTPNP 588

  Fly   608 SDSNEEK---ALNLSSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAF 669
            .|.:.||   ...|.:.:|||.|.|:..|. :..|::.|.|::..:|..|.:|:::|||||||||
Mosquito   589 CDPHPEKLQTQFTLMNCMWFAIGSLMQQGC-DFLPKAVSTRMVAGMWWFFTLIMISSYTANLAAF 652

  Fly   670 LVLERPKTKLSGINDARLRNTMENLTCATVKGSSVDMYFRRQVELSN------MYRTMEANN--- 725
            |.:||..:.:....|...:.   .:....::|.|...:||.    ||      |:..||:..
Mosquito   653 LTVERMDSPIESAEDLAKQT---KIKYGALRGGSTAAFFRD----SNFSTYQRMWSFMESARPSV 710

  Fly   726 -YATAEQAIQDVKKGK-LMAFIWDSSRLEYEASKDCELVTAGELFGRSGYGIGLQKGSPWTDAVT 788
             .|:..:.::.|.||| ..||:.:|:.:||...::|||...|.:....||||.:...||:..|::
Mosquito   711 FTASNIEGVERVVKGKGSYAFLMESTSIEYVIERNCELTQVGGMLDSKGYGIAMPPNSPFRTAIS 775

  Fly   789 LAILEFHESGFMEKLDKQWIFH----GHVQQNCELFEKTPNTLGLKNMAGVFILVGVGIAGGVG- 848
            .|:|:..|.|.:..|..:|...    |..:.:......|.|.|||.|:.|||::    :.||:|
Mosquito   776 GAVLKLQEEGKLHILKTRWWKEKRGGGSCRDDTSKSSSTANELGLANVGGVFVV----LMGGMGV 836

  Fly   849 ---LIIIEVIYKKHQVKKQKR-LDIARHAADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGT 909
               :.:.|.::|..:|..::| :.:....|.:.|..:::.:      |..:....|       ||
Mosquito   837 ACVIAVCEFVWKSRKVAVEEREVSLCSEMASELRFALKRNR------AQPKHAGSG-------GT 888

  Fly   910 ISLAVDKRRYPRLGQRLGPERAWPGDAA 937
            :              |....||.|.|:|
Mosquito   889 L--------------RTASSRASPKDSA 902

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	37..405	CDD:380602	83/423 (20%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	128/419 (31%)
		CaM_bdg_C0	854..882	CDD:402271	5/28 (18%)
KaiR1D	XP_061498559.1	None