Protein Alignment Nmdar1 and CG11155

DIOPT Version :10

• Sequence 1: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Sequence 2: NP_651941.2
• Gene: CG11155 / 43822
• FlyBaseID: FBgn0039927
• Length: 910
• Species: Drosophila melanogaster
• Alignment Length: 958
• Identity: 247/958 - (25%)
• Similarity: 416/958 - (43%)
• Gaps: 181/958 - (18%)

  Fly    36 PSTYNIGGVLSNSDSEEHFSTTIKH----------------LNFDQQYVPRKVTYYDKTIRMDKN 84
            |....:|.:.:..:.|....:..|:                |.:|.:||||     |.:.|..|.
  Fly    40 PPVIRVGAIFTEDERESSIESAFKYAIYRINKEKTLLPNTQLVYDIEYVPR-----DDSFRTTKK 99

  Fly    85 -------PIKTVFNVCDKLIENRVYAVVVSHEQTSGDLSPAAVSYTSGFYSIPVIGISSR-DAAF 141
                   .::.:|...|.|:.:.|.::..:                   |.||  .|..| |..:
  Fly   100 VCSQLEAGVQAIFGPTDALLASHVQSICEA-------------------YDIP--HIEGRIDLEY 143

  Fly   142 SDKNIHVSFLRTVPPYYHQADVWLEMLSHFAYTKVIIIHSSD----------TDGRAILGRFQTT 196
            :.|...::.   .|.:......:.:::.:..:|||.||:..|          |:.:|.:...|.:
  Fly   144 NSKEFSINL---YPSHTLLTLAYRDIMVYLNWTKVAIIYEEDYGLFNLMHSSTETKAEMYIRQAS 205

  Fly   197 SQTYYD---DVDVRATVELIVEFEPK-LESFTEHLIDMKTAQSRVYLMYASTEDAQVIFRDAGEY 257
            ..:|..   .:..:...::||:..|. ::||...::.::....|.:.|: :|.|.:....:...|
  Fly   206 PDSYRQVLRAIRQKEIYKIIVDTNPSHIKSFFRSILQLQMNDHRYHYMF-TTFDLETYDLEDFRY 269

  Fly   258 N-----------MTGEGHVWIVTEQALFSNNTPDGVLG---LQLEHAHSDKGHIRDSVYVLASAI 308
            |           :..:.::.::.:.....:|..|.:.|   :|.|.|     .:.||||..|:.:
  Fly   270 NSVNITAFRLVDVDSKRYLEVINQMQKLQHNGLDTINGSPYIQTESA-----LMFDSVYAFANGL 329

  Fly   309 K--EMISNETIAEAPKDCGDSAVNWESGKRLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINI 371
            .  .:.:::........| .|...|..|..|:..:.:....|.||.|.|.:....|:. .|::.:
  Fly   330 HFLNLDNHQNFYIKNLSC-TSDQTWNDGISLYNQINAAITDGLTGTVQFVEGRRNIFK-LDILKL 392

  Fly   372 REQQKKHVVGKFSYDSMRAKMRMRINDSEIIWPGKQRRKPEGIMIPTHLRLLTIEEKPFVYVRRM 436
            : |:|...||.:..|.     .:.|:|....:        :..:....|.::|.||:|:|.|:
  Fly   393 K-QEKIQKVGYWHPDD-----GVNISDPTAFY--------DSNIANITLVVMTREERPYVMVK-- 441

  Fly   437 GDDEFRCEPDERPCPLFNNSDATAN-EFCCRGYCIDLLIELSKRINFTYDLALSPDGQFGHYILR 500
                             .:.:.|.| .|  .|:|||||..::.::.|.|.:.|.||..:|.||..
  Fly   442 -----------------EDKNLTGNLRF--EGFCIDLLKAIATQVGFQYKIELVPDNMYGVYIPE 487

  Fly   501 NNTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERAEYIEFSKPFKYQGITILEKKP-SRSST 564
            .|:        |.|::.||:..|||:.||.:|||..|...|:|:|||...||.||.|.| |:.:.
  Fly   488 TNS--------WNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKVPTSQPTR 544

  Fly   565 LVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSHSDSNE----EKALNLSSAVWFA 625
            |.||:.|.:..:|:.|:.:..:|:..|:::.||||: .:|..|....|    |...::|::.||.
  Fly   545 LFSFMNPLAIEIWLYVLAAYILVSFALFVMARFSPY-EWKNPHPCYKETDIVENQFSISNSFWFI 608

  Fly   626 WGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTKLSGINDARLRNT 690
            .|..|..|.|. .|::.|.|::|..|..|.:||::||||||||||.:||   .:|.|..|.....
  Fly   609 TGTFLRQGSGL-NPKATSTRIVGGCWFFFCLIIISSYTANLAAFLTVER---MISPIESASDLAE 669

  Fly   691 MENLTCATVKGSSVDMYFR-RQVEL-SNMYRTMEANNYA----TAEQAIQDVKKGKLMAFIWDSS 749
            ...::..|::|.|...:|| .::.: ..|:|.||....|    |.|..|:.|.:|. .||:.:|:
  Fly   670 QTEISYGTLEGGSTMTFFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVMEGS-YAFLMEST 733

  Fly   750 RLEYEASKDCELVTAGELFGRSGYGIGLQKGSPWTDAVTLAILEFHESGFMEKL-DKQWIFHGHV 813
            .|:|...:||.|...|.|....||||...|||||.|.::|||||..|.|.::.| ||.|...|.|
  Fly   734 MLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQILYDKWWKNTGDV 798

  Fly   814 QQNCELFEKT----PNTLGLKNMAGVFILVGVGIAGGVGLIIIEVIY---KKHQVKKQ------- 864
               |...:|:    .|.||::|:.|||:::..|:|..|.:.|.|..:   |....:.|
  Fly   799 ---CNRDDKSKESKANALGVENIGGVFVVLLCGLALAVVVAIFEFCWNSRKNLNTENQSLCSEMA 860

  Fly   865 KRLDIARHA-ADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGTIS 911
            :.|..|.|. ..|.|....||..:..|..          .|:.|..:|
  Fly   861 EELRFAMHCHGSKSRHRPRKRSCLNCSSV----------PTYVPSNVS 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	37..405	CDD:380602	75/421 (18%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	144/413 (35%)
		CaM_bdg_C0	854..882	CDD:402271	7/38 (18%)
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..413	CDD:380605	74/411 (18%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	141/403 (35%)
		Lig_chan	554..828	CDD:459656	99/282 (35%)