Protein Alignment Nmdar1 and Ir85a

DIOPT Version :10

• Sequence 1: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Sequence 2: NP_649833.1
• Gene: Ir85a / 41052
• FlyBaseID: FBgn0037630
• Length: 605
• Species: Drosophila melanogaster
• Alignment Length: 630
• Identity: 110/630 - (17%)
• Similarity: 221/630 - (35%)
• Gaps: 170/630 - (26%)

  Fly   335 KRLFQYLKSRNITGETGQV-----------------AFDDNGDRIYAGYDVINIREQQKKHVVGK 382
            |.||.|.:::.....|||:                 |..|:|..:|......||.:..:..::.|
  Fly    50 KVLFVYFENQTSHEHTGQILKEVTKCDISNQNTPLEAVKDDGILMYMVMITTNISQPLELSLIRK 114

  Fly   383 FSYDSMRAKMRMRINDSEII---WPGKQRRKPEGIMIPTHL-------RLLTIEEKPFVYVRRMG 437
            .|....|:.:.:.:.|::.:   |.....|:...|.:...:       ||......||:
  Fly   115 KSAAKHRSHVFLLVRDADTVSDAWMRASFRQFWKIWLLNIVILYWRDGRLNAYRYNPFM------ 173

  Fly   438 DDEFRCEPDERP--CP----LFNNS---------------DATANEFCCRGYCID----LLIELS 477
             |.:....|.:|  .|    ||..:               |.....|..:|..:.    |...::
  Fly   174 -DNYLIPVDNKPNEVPTLEQLFPKTIPNMQRKPLRMCIYKDDVRAIFWRQGTILGTDGLLAAYVA 237

  Fly   478 KRINFTYDLALSPDGQFGHYILRNNTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERAEYIE 542
            :|:|.|  :.::....:.::.|.::...:.:.||:   :...:|.|   .:.|.|...:....:.
  Fly   238 ERLNAT--MMITRPHSYNNHNLSSDICFLEVAKEY---VDVAMNIR---FLVPDTFRKQAESTVS 294

  Fly   543 FSKPFKYQGITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSH 607
            .::    ..:.::..|...:.|..:..:.|.:.:|.|::|||.|..:..|:|.  |..||..:.
  Fly   295 HTR----DDLCVIVPKAKTAPTFWNIFRSFGSLVWALILVSVLVANVFCYILK--SEVGRVPMQ- 352

  Fly   608 SDSNEEKALNLSSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVL 672
                           .||..:.:..   ...|.:.|.|:..:.|..|.::|.:::..||.:.:|.
  Fly   353 ---------------LFAGALTMPM---TQIPPNHSIRLFLIFWLYFGLLICSAFKGNLTSMMVF 399

  Fly   673 E---------------------RPK--------TKLSGINDARLRNTMENLTCATVKGSSVDMYF 708
            :                     ||:        ..|...:::|:|..|       ::.|...||
  Fly   400 QPYLPDINQLGALARSHYHIIIRPRHVKHIQHFLTLGHKHESRIREQM-------LEVSDTQMY- 456

  Fly   709 RRQVELSNMYRTMEANNYATAEQAIQD---VKKGKLMAFIWDSSRLEYEASKDCELVTAGELFGR 770
              ::..:|..|......|..|...:..   :..|:.:..:.:|..:.:.|.
  Fly   457 --EMMRNNDIRFAYLEKYHIARFQVNSRVHMHLGRPLFHLMNSCLVPFHAV-------------- 505

  Fly   771 SGYGIGLQKGSPWTDAVTLAILEFHESGFMEKLDKQW---IFHGHVQQNCELFEK-------TPN 825
              |.:  ..|||:...:...|...||.||    ::.|   :....::...::..:       .|.
  Fly   506 --YIV--PYGSPYLGFLDSLIRSSHEFGF----ERYWDRIMNSAFIKSGVKVVNRRRGSGNDEPV 562

  Fly   826 TLGLKNMAGVFILVGVGIAGGVGLIII--EVIYKKHQVKKQKRLD 868
            .|.|::...||.|..|||  |:..|::  |.:...:.:...||.|
  Fly   563 VLKLQHFHAVFALWLVGI--GMACIVLAWEHLTHNYNLAVTKRRD 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	37..405	CDD:380602	18/89 (20%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	75/467 (16%)
		CaM_bdg_C0	854..882	CDD:402271	3/15 (20%)
Ir85a	NP_649833.1	None