Protein Alignment Nmdar1 and Ir75a

DIOPT Version :9

• Sequence 1: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Sequence 2: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 812
• Identity: 143/812 - (17%)
• Similarity: 298/812 - (36%)
• Gaps: 247/812 - (30%)

  Fly    92 VCDKLIENRVYAVVVSHEQTSGDLSPAAVSYTSGFYSIPVIGISSRDAAFSDKNIHVS--FLRTV 154
            |.|.|:::|:..:|:.|                              ...||:::..:  |::.:
  Fly    10 VLDNLVQSRIGFIVLFH------------------------------CWQSDESLKFAQQFMKPI 44

  Fly   155 PP--YYHQADVWLEMLSHFAYTKVIIIHSSDTDGRAILGRFQTTSQTYYDDVDVRATVELIVEFE 217
            .|  .|||   :::|.....::.:.:         :.:|..|.|...|
  Fly    45 HPILVYHQ---FVQMRGVLNWSHLEL---------SYMGHTQPTLAIY----------------- 80

  Fly   218 PKLESFTEHLIDMKTAQSRVYLMYASTEDAQVIFRDAGEYNMTGEGHVWIVTEQALFSNNTPDGV 282
                      :|:|..|::..|..||.|..         ||   :.:.|:              :
  Fly    81 ----------VDIKCDQTQDLLEEASREQI---------YN---QHYHWL--------------L 109

  Fly   283 LGLQLEHAHSDK-GHIRDSVYVLASAIKEMI--SNETIAEAPKDCGDSAVNWESGKRLFQYLKSR 344
            :|.|.:....|. |....|:....|.:||.|  :|:::|.|..|.      :.:||.:...|
  Fly   110 VGNQSKLEFYDLFGLFNISIDADVSYVKEQIQDNNDSVAYAVHDV------YNNGKIIGGQL--- 165

  Fly   345 NITGETGQVAFDDNGDRIYAGYDVINIREQQKKHVVGKFSYDSMRAKMRMRINDSEIIWPGKQRR 409
            |:|| :.:::.|....|             :.:|:    |....|:|...|...::::
  Fly   166 NVTG-SHEMSCDPFVCR-------------RTRHL----SSLQKRSKYGNREQLTDVV------- 205

  Fly   410 KPEGIMIPTHLRLLT-IEEKPFVYVRRMGDDE---FRCEPDERPCPLFNNSDATANEFCCRGYCI 470
                      ||:.| :.::|..    :.|||   |          |...:|...:.....|:.:
  Fly   206 ----------LRVATVVTQRPLT----LSDDELIRF----------LSQENDTHIDSLARFGFHL 246

  Fly   471 DLLIE--LSKRINFTYDLALSPDGQFGHYILRNNTGAMTLRKEWTGLIGELVNERADMIVAPLTI 533
            .|::.  |..::.|.:..:.|.....|                  |.:|.:|::.||:...|...
  Fly   247 TLILRDLLHCKMKFIFSDSWSKSDVVG------------------GSVGAVVDQTADLTATPSLA 293

  Fly   534 NPERAEYIEFSKPFKYQGITILEKKPSRSSTLVS-----------FLQPFSNTLWIL---VMVSV 584
            ...|.:|:.          .|:|....||..:..           ||||||..:|.|   |:..:
  Fly   294 TEGRLKYLS----------AIIETGFFRSVCIFRTPHNAGLRGDVFLQPFSPLVWYLFGGVLSLI 348

  Fly   585 HVVALVLYLLDRFSPFGRFKLSHSDSNEEKALNLSSAVWFAWGV--LLNSGIGEGTPRSFSARVL 647
            .|:..:.:.::......|::|.:..|       |.|....::|.  :.:|.:   .|||...|::
  Fly   349 GVLLWITFYMECKRMQKRWRLDYLPS-------LLSTFLISFGAACIQSSSL---IPRSAGGRLI 403

  Fly   648 GMVWAGFAMIIVASYTANLAAFLVLERPKTKLSGIN---DARLRNTMENL--TCATVKGS---SV 704
            .......:.|:...||:.:.:.|:....|:|:..:.   ::.|...:|.|  |.:.:..|   .:
  Fly   404 YFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQLAESSLTVGLEPLPFTKSYLNYSRLPEI 468

  Fly   705 DMYFRRQVELSNMYRTMEANNYATAEQAIQDVKKGKLMAFIWDSS------RLEYEASKDCELVT 763
            .::.:|::|    .:|.....:..|||.:..|:......:::::|      ...:.|.:.|:|
  Fly   469 HLFIKRKIE----SQTQNPELWLPAEQGVLRVRDNPGYVYVFETSSGYAYVERYFTAQEICDL-- 527

  Fly   764 AGELFGRSG--YGIGLQKGSPWTDAVTLAILEFHESGFMEKLDKQWIFHGHVQQNCELFEKTPNT 826
             .|:..|..  :...|.:.|.:.:...|..|...|:|...|....|:   |::.:| :.:....|
  Fly   528 -NEVLFRPEQLFYTHLHRNSTYKELFRLRFLRILETGVYRKQRSYWV---HMKLHC-VAQNFVIT 587

  Fly   827 LGLKNMAGVFILVGVGIAGGVGLIIIEVIYKK 858
            :|::.:|.:.:::.......|.::::|:.:|:
  Fly   588 VGMEYVAPLLLMLICADILVVVILLVELAWKR 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	12..405	CDD:107374	54/319 (17%)
		ANF_receptor	58..371	CDD:279440	49/285 (17%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	82/438 (19%)
		HisJ	451..>558	CDD:223904	18/108 (17%)
		Periplasmic_Binding_Protein_Type_2	<516..651	CDD:304360	32/150 (21%)
		Lig_chan	575..838	CDD:278489	52/283 (18%)
		CaM_bdg_C0	854..882	CDD:287524	1/5 (20%)
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	52/286 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462790
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940