Protein Alignment Nmdar1 and Ir64a

DIOPT Version :10

• Sequence 1: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Sequence 2: NP_647962.1
• Gene: Ir64a / 38616
• FlyBaseID: FBgn0035604
• Length: 859
• Species: Drosophila melanogaster
• Alignment Length: 979
• Identity: 175/979 - (17%)
• Similarity: 320/979 - (32%)
• Gaps: 316/979 - (32%)

  Fly    55 STTIKHLNFDQQYVPRKVTYYDKTIRMDKNPIKTVFNVCDKLIENRVYAVVVSHEQTSGDLSPAA 119
            |:.|...:.|.:::|| :||:                .|.|           .|.||...:..||
  Fly    41 SSLILQFSQDYKHIPR-ITYF----------------TCQK-----------PHLQTPNQIPNAA 77

  Fly   120 VSYTSGFYSIPVIGISSRDAAFSDKNIHVSFLRTVPPYYHQADVWLEMLSHFAYTKVIIIHSSDT 184
                           ..|| ||:.||..:  ::::  |..:..|.:.:|.        ::..|.|
  Fly    78 ---------------EHRD-AFAAKNFQL--IKSL--YESELFVRIVLLD--------VLAQSPT 114

  Fly   185 DGR------AILGRF-QTTSQTYYDDVDVRATVELIVEFEPKLESFTE-HLIDMKT-AQSRVYLM 240
            .||      ...|.| ||.||...:...:...:        ::|:..: .::|:.. |.||.:|.
  Fly   115 SGRPNRPGNGPTGGFSQTPSQAQSNSEWLEGVL--------RMEALRQIAVVDLACGAVSRRFLE 171

  Fly   241 YASTEDAQVIFRDAGEYNMTGEGHVWIVTEQALF--SNNTPDGVLGLQLEHAHSDKGHIRDSVYV 303
            .||   |::::         .|...|::.|...:  ...|.:|       ....|.|.:.:
  Fly   172 LAS---AKMLY---------SEKFHWLLIEDFAWHGRTQTAEG-------SGKRDDGEMEE---- 213

  Fly   304 LASAIKEMISNETIAEAPKDCGDSAVNWESGKRLF---QYLKSRNITGETGQVAFDD-NGDRIYA 364
                 :|....:..|...:|. .|..::..|..|:   :...::.::.......||. |....|.
  Fly   214 -----EEPPGQQIQATDDEDL-PSIESFLGGMNLYMNTELTLAKRMSEAAHYTLFDVWNPGLNYG 272

  Fly   365 GYDVINIREQQKKHVVGKFSYDSMRAKMRMRINDSEIIWPGKQRRKPEGIMIPTHLRLLTIEEKP 429
            |:  :|:.|      :|.|:                         ..|||.:.|..|..:.
  Fly   273 GH--VNLTE------IGSFT-------------------------PTEGIQLHTWFRTTST---- 300

  Fly   430 FVYVRRMGDDE---FRCEPDERPCPLFNNSDATANEFCCRGYCIDLLIELSKRINFTYDLALSPD 491
               |||..|.:   .||      ..:..|.:.|........:.:...|:...|.||...:|:...
  Fly   301 ---VRRRMDMQHARVRC------MVVVTNKNMTGTLMYYLTHTMSGHIDTMNRFNFNLLMAVRDM 356

  Fly   492 GQFGHYILRNNTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERAEYIEFS-KPFKYQGITIL 555
            ..:...:.|..:........:.|:||.|:....|:..||:....||.::|:.: :.:..:...|.
  Fly   357 FNWTFVLSRTTSWGYVKNGRFDGMIGALIRNETDIGGAPIFYWLERHKWIDVAGRSWSSRPCFIF 421

  Fly   556 EKKPSRSSTLVSFLQPFSNTLWILV---------------------------------------- 580
            ....|.....:.|||||:|.:|||:
  Fly   422 RHPRSTQKDRIVFLQPFTNDVWILIVGCGVLTVFILWFLTTIEWKLVPHDGSALIKPKGGAPPRH 486

  Fly   581 -----------------MVSVHVVA------------------------------LVLYLLDRFS 598
                             :.:|.||.                              |..|:.||
  Fly   487 HYQQQQQQEQVEAPVRPITAVSVVVSKEKVEEKQEEYEDSTPIDAGTLWQRCYQKLNKYIKDR-- 549

  Fly   599 PFGRFKLSHSDSNEEKALNLSSAVWFAWGVLLNSGIGEGTPRSF-SARVLGMVWAGFAMIIVASY 662
                 |.....:.|...|.|.|.::|. |::...|:|..|  || |.|.:.:....|:..|...|
  Fly   550 -----KAKQKKAPERVGLFLESVLFFV-GIICQQGLGFST--SFVSGRCIVITSLLFSFCIYQFY 606

  Fly   663 TANLAAFLVLERPKT--KLSGINDARLRNTMENLT------CATVKGSSVDMYFRR--------- 710
            :|::...|::|:|||  .||.:..:.|:..||::.      ..|....|:::|.::
  Fly   607 SASIVGTLLMEKPKTIKTLSDLVHSSLKVGMEDILYNRDYFLHTKDPVSMELYAKKITSVPTTKE 671

  Fly   711 --------------QVELSNMYRTM----EANNYATAEQAIQ--DVKKGKL----MAFIWDSSR- 750
                          ..:.:..||.:    |...:|....|..  |.:.|.|    .||..|.:.
  Fly   672 NEADEDEPVDPNPVSTDPAKSYRDIVHSHETGAHAKDNAASNWLDPETGLLRHLGFAFHVDVAAA 736

  Fly   751 ----LEYEASKD-CELVTAGELFGRSGYGIGLQKGSPWTDAVTLAILEFHESGFMEKLDKQWIFH 810
                .|..:.:| |:|........:....| :||.||....::..:....|:|.:......|  |
  Fly   737 YKIIAETFSEQDICDLTEVSMFPPQKTVSI-MQKNSPMRKVISYGLRRVTETGILTYHFNVW--H 798

  Fly   811 GHVQQNCELFEKTPNTLGLKNMAGVFILVGVGIAGGVGLIIIEVIYKKHQVKKQKRLDIARHAAD 875
            .......:..|.:...:.:..::...:::....|..:.::..|::|.|.    ..|:.:
  Fly   799 SRKPPCVKKIETSDLHVDMDTVSSALLILLFSYAITLMILGTEILYSKW----HNRIQL------ 853

  Fly   876 KWRG 879
            ||.|
  Fly   854 KWVG 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	37..405	CDD:380602	64/364 (18%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	99/539 (18%)
		CaM_bdg_C0	854..882	CDD:402271	6/26 (23%)
Ir64a	NP_647962.1	Periplasmic_Binding_Protein_Type_2	351..>465	CDD:473866	23/113 (20%)
		Lig_chan	563..828	CDD:459656	53/270 (20%)