DRSC/TRiP Functional Genomics Resources

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Protein Alignment Nmdar1 and Ir40a

DIOPT Version :9

Sequence 1:NP_730940.1 Gene:Nmdar1 / 40665 FlyBaseID:FBgn0010399 Length:997 Species:Drosophila melanogaster
Sequence 2:NP_610140.4 Gene:Ir40a / 35449 FlyBaseID:FBgn0259683 Length:732 Species:Drosophila melanogaster


Alignment Length:486 Identity:104/486 - (21%)
Similarity:191/486 - (39%) Gaps:121/486 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   472 LLIELSKRINFTYDLALSPDGQFGHYILRNNTGAMTLRKEWTGLIGELVNERADMIVAPLTINPE 536
            ||:.|||.:||.:....:|....|.  :|:..|..: ...:||.||.|.:.:||..:..:.::.|
  Fly   265 LLMLLSKHMNFRFKYIEAPGRTQGS--MRSEDGKDS-NDSFTGGIGLLQSGQADFFLGDVGLSWE 326

  Fly   537 RAEYIEFSKPFKYQGITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFG 601
            |.:.||||..............|.|.:..::.::||...:|..:::::.....:.|.:.......
  Fly   327 RRKAIEFSFFTLADSGAFATHAPRRLNEALAIMRPFKQDIWPHLILTIIFSGPIFYGIIALPYIW 391

  Fly   602 RFKLSHSDSNE---------------EKALNL----------------SSAVWFAWGVLLNSGIG 635
            |.:.::||...               .:.|.|                ...:||...:.|.....
  Fly   392 RRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQSCN 456

  Fly   636 EGTPRSFSARVLGMV-WAGFAMIIVASYTANLAAFLVLERPKTKLSGINDARLR--NTMENLTCA 697
            | ....:.|:.|.:| |.....::...|:|.|.:  ...||         ||..  ||::.|..|
  Fly   457 E-LHNGYRAKFLTIVYWIAATYVLADVYSAQLTS--QFARP---------AREPPINTLQRLQAA 509

  Fly   698 TV----------KGSSVDMYFRRQVELSN---MYRTMEANNYATAEQAIQDVKKGKLMAFIWDSS 749
            .:          :.||::|       |.|   ::|.:    ||...|.:.:..:|..:..:....
  Fly   510 MIHDGYRLYVEKESSSLEM-------LENGTELFRQL----YALMRQQVINDPQGFFIDSVEAGI 563

  Fly   750 RLEYEASKDCELVTAGE--LFGRSGYG----------------IGLQKGSPWTDAVTLAILEFHE 796
            :|..|..:|..::...|  .|....||                :.:|.|.|:..::...:::..|
  Fly   564 KLIAEGGEDKAVLGGRETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFE 628

  Fly   797 SGFMEKLD-----KQW-------IFHGHVQ-QNCELFEKTP-------NTLGLKNMAGVFILVGV 841
            ||.::|:.     ||:       |:.|.|| :|.|.:.:|.       :.|.|:.:.|.||.:||
  Fly   629 SGILDKMTAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGV 693

  Fly   842 G-IAGGVGLIIIEVIYKKHQVKKQKRLDIAR 871
            | :|.|| ::::|:::.|        ||.||
  Fly   694 GSLAAGV-ILLLEIVFIK--------LDQAR 715

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Nmdar1NP_730940.1 PBP1_iGluR_NMDA_NR1 12..405 CDD:107374
ANF_receptor 58..371 CDD:279440
PBP2_iGluR_NMDA_Nr1 417..818 CDD:270437 85/423 (20%)
HisJ 451..>558 CDD:223904 24/85 (28%)
Periplasmic_Binding_Protein_Type_2 <516..651 CDD:304360 29/166 (17%)
Lig_chan 575..838 CDD:278489 63/347 (18%)
CaM_bdg_C0 854..882 CDD:287524 5/18 (28%)
Ir40aNP_610140.4 PBP2_LTTR_substrate 216..338 CDD:330233 24/75 (32%)
Periplasmic_Binding_Protein_Type_2 297..>391 CDD:328725 19/94 (20%)
Periplasmic_Binding_Protein_Type_2 <496..637 CDD:328725 29/151 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45463007
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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