Protein Alignment Nmdar1 and LOC3289757

DIOPT Version :10

• Sequence 1: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Sequence 2: XP_061498361.1
• Gene: LOC3289757 / 3289757
• VectorBaseID: AGAMI1_010049
• Length: 949
• Species: Anopheles gambiae
• Alignment Length: 1014
• Identity: 239/1014 - (23%)
• Similarity: 408/1014 - (40%)
• Gaps: 266/1014 - (26%)

  Fly    12 LFGLAIVLLVAPIDAAQRHTASDNPSTYNIGGVL--SNSDSEEHFSTTIKHLN----------FD 64
            ||.|.::..:|.:.........:......|||:.  :..|.|..|...::.:|          .:
Mosquito    12 LFALLLITQLAAVIGYHHGDLDETVEHIKIGGLFDGATEDVELAFQYAVEAVNNEKLSYSNYQLE 76

  Fly    65 QQYVPRKVTYYD------KTIRMDKNPIKTVF------------NVCDKLIENRVYAVVVSHEQT 111
            .|.|  :|.|.|      |..|:.|..:..:|            :|||:        ..:.|.:|
Mosquito    77 AQAV--QVKYGDQFDASKKLCRLLKTGVAGIFGPSSPKSALHVQSVCDE--------KEMPHIET 131

  Fly   112 SGDLSPAAVSYTSGFYSIPVIGISSRDAAFSDKNIHVSFLRTVPPYYH-QADVWLEMLSHFAYTK 175
            ..|      :||    .:|.:            |:|        |:.| ...|:|:::..|.:..
Mosquito   132 RWD------AYT----KLPTL------------NLH--------PHPHIMGRVFLDLVVAFEWKS 166

  Fly   176 VIIIHSSDTDGRAILGRFQTTSQTYYDDVDVRATVELIVEFEPKLESFTEHLIDM---------- 230
            ..:::.|   |..:.|                 ..:|:..::||..:.|...:|:
Mosquito   167 FTVLYES---GPWLPG-----------------IADLLKMYDPKGYTVTVRQLDLGLNGNYRAVL 211

  Fly   231 ---KTAQSRVYLMYASTEDAQVIFRDAGEYNMTGEGHVWIVTEQALFSNNTPD---------GVL 283
               |.::.:..::..|.:....:.|.|.:..:..:.|..|||...|   :|.|         .:.
Mosquito   212 RRVKLSEDKRIILACSIDSMPEVLRQAQQVGLLTDHHQIIVTSLDL---HTIDLEPYQYSGTNIT 273

  Fly   284 GLQLEHAHSDKGHIR----------------------------------DSVYVLASAIKEMISN 314
            |::|.....||  ||                                  |:|.:.|.|:|.:|.:
Mosquito   274 GVRLIDPEEDK--IRQVADFLNASQIAKTLELQDGLNPAKMRVETALMYDAVLLFAEALKHLIGS 336

  Fly   315 E---TIAEAPKDCGDSAVNWESGKRLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINIREQQK 376
            |   .:......|.|:| .|::|..:..|:||..|.|.|..:.||..|.|.....|:|.:
Mosquito   337 EPAHLLEPIALRCDDTA-TWKNGYSVINYMKSSTIHGLTRSIRFDHQGHRSDFLLDIIEL----- 395

  Fly   377 KHVVGKFSYDSMRAKMRMRINDSEIIWPGKQ----RRKPEGIMIP---------THLRLLTIEEK 428
                |....:.:.            :|...:    .||.|..::.         |.| :||....
Mosquito   396 ----GPAGLEKVG------------VWNSTEGLNFTRKKEQTLLAFDDGTLQNRTFL-VLTAISP 443

  Fly   429 PFVYVRRMGDDEFRCEPDERPCPLFNNSDATANE-FCCRGYCIDLLIELSKRINFTYDLALSPDG 492
            |:..::            :.|..|      |.|| |  .|:.|||:.|||..:.|.|...|..||
Mosquito   444 PYGMLK------------DSPVKL------TGNERF--EGFGIDLIHELSLMLGFNYTFILQEDG 488

  Fly   493 QFGHYILRNNTGAMTLRKEWTGLIGELVNERADMIVAPLTINPERAEYIEFSKPFKYQGITILEK 557
            .:|.  |..:|      |:|.|::.||:..|||:.:..|||..:|...::|:.||...||:||.:
Mosquito   489 VYGS--LNRDT------KKWNGMVLELLEWRADLAITDLTITSDRESAVDFTMPFMNLGISILYR 545

  Fly   558 KPSRS-STLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSP---FGRFKLSHSDSNEEKALNL 618
            ||::. .:|.||:.|||..:|:.:..:..:|::.|::|.|.||   ...:.........|...:.
Mosquito   546 KPTKEPPSLFSFMSPFSKQVWLYLGGAYMMVSMSLFILGRISPKEWDNPYPCIEEPEELENQFSF 610

  Fly   619 SSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTKLSGIN 683
            |:::||..|.||..| .|..|::.:.|.:..:|..|.:|:|:||||||||||.:|:   .:|.|:
Mosquito   611 SNSMWFTIGALLQQG-SEIAPKAPATRAVASIWWFFTLIMVSSYTANLAAFLTVEQ---VVSPIS 671

  Fly   684 DARLRNTMENLTCA--TVK------GSSVDMYFRRQVE---LSNMYRTMEANN---YATAEQAIQ 734
            :|      |:|..|  |:|      ||::.  |.:..|   .:.||:.|.||.   .::..:.:|
Mosquito   672 NA------EDLAAAGGTIKYGAKRDGSTIS--FFKDAEYGTYAKMYQYMMANQELLTSSNPEGLQ 728

  Fly   735 DVKKGKLMAFIWDSSRLEYEASKDCELVTAGELFGRSGYGIGLQKGSPWTDAVTLAILEFHESGF 799
            .||. :..||:.:|:.:||...::|::...|.|....||||.::|.||:..|::.|:|...|.|.
Mosquito   729 RVKT-ENYAFLMESTSIEYIVERECDVTQIGGLLDDKGYGIAMRKNSPYRSALSEAVLRLQEQGV 792

  Fly   800 MEKLDKQWIFH----GHVQQNCELFEKTPNTLGLKNMAGVF--ILVGVGIAGGVG----LIIIEV 854
            :..|.::|...    |...|:..  :.....|.:.|:.|||  :.||...|...|    ..:|..
Mosquito   793 LTSLKRKWWKEKRGGGACSQSTS--DDGAEELDMDNVGGVFFVLFVGCSFASLFGCCELFFVIAH 855

  Fly   855 IYKKHQVKKQKRLDIARHAADKWRGT---IEKRKTIRAS 890
            ..::|:|..::.|........|..|.   :..||:..||
Mosquito   856 RARRHKVPFREELMAELRFVAKCHGNTKPVRHRKSSSAS 894

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	37..405	CDD:380602	83/457 (18%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	130/432 (30%)
		CaM_bdg_C0	854..882	CDD:402271	5/30 (17%)
LOC3289757	XP_061498361.1	None