Protein Alignment Nmdar1 and Nmdar1

DIOPT Version :10

• Sequence 1: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Sequence 2: XP_321646.4
• Gene: Nmdar1 / 1281696
• VectorBaseID: AGAMI1_011915
• Length: 966
• Species: Anopheles gambiae
• Alignment Length: 990
• Identity: 749/990 - (75%)
• Similarity: 827/990 - (83%)
• Gaps: 34/990 - (3%)

  Fly    11 PLFGLAIVLLVAPIDAAQRHTASDNPSTYNIGGVLSNSDSEEHFSTTIKHLNFDQQYVPRKVTYY 75
            |...:.:.|::.....||:.|.|::||.|||||||||::||.||:|.|.|||||||||||..|||
Mosquito     8 PASCMLLSLMIPQALLAQKPTGSESPSYYNIGGVLSNNESESHFATVIAHLNFDQQYVPRGTTYY 72

  Fly    76 DKTIRMDKNPIKTVFNVCDKLIENRVYAVVVSHEQTSGDLSPAAVSYTSGFYSIPVIGISSRDAA 140
            |||||:|||||||..|||..||..||||||||||.| |||||||||||||||.|||||||||:||
Mosquito    73 DKTIRIDKNPIKTALNVCKHLISRRVYAVVVSHEPT-GDLSPAAVSYTSGFYQIPVIGISSREAA 136

  Fly   141 FSDKNIHVSFLRTVPPYYHQADVWLEMLSHFAYTKVIIIHSSDTDGRAILGRFQTTSQTYYDDVD 205
            ||||||||||||||||||||||||||:||||.||||||||||||||||:||||||||||.|||:|
Mosquito   137 FSDKNIHVSFLRTVPPYYHQADVWLEILSHFGYTKVIIIHSSDTDGRAVLGRFQTTSQTNYDDID 201

  Fly   206 VRATVELIVEFEPKLESFTEHLIDMKTAQSRVYLMYASTEDAQVIFRDAGEYNMTGEGHVWIVTE 270
            ||||||.||||||||:||:.:|:|||||||||||:|||.|||.||||||..:|||..||:|||||
Mosquito   202 VRATVESIVEFEPKLDSFSSYLMDMKTAQSRVYLLYASQEDAYVIFRDAAIHNMTEYGHIWIVTE 266

  Fly   271 QALFSNNTPDGVLGLQLEHAHSDKGHIRDSVYVLASAIKEMISNETIAEAPKDCGDSAVNWESGK 335
            |||.:||||.|::||:|.:|.::..||:|::|:||||||||..||||.||||||.||.|.|||||
Mosquito   267 QALSANNTPTGIIGLKLNNAENETDHIKDAIYILASAIKEMTVNETITEAPKDCDDSGVIWESGK 331

  Fly   336 RLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINIREQQKKHVVGKFSYDSMRAKMRMRINDSE 400
            |||.|||:|||.||||||||||||||:||.|||||:.|......||.|.|||.:.|||::||||.
Mosquito   332 RLFGYLKTRNIRGETGQVAFDDNGDRMYAEYDVINVHENHSFVKVGSFHYDSEKRKMRLKINDSS 396

  Fly   401 IIWPGKQRRKPEGIMIPTHLRLLTIEEKPFVYVRRMGDDEFRCEPDERPCPLFNNSDATANEFCC 465
            |.|||...:|||||||||||::||||||||||.|::.|||..|..||..||.||.::....|:||
Mosquito   397 ITWPGNTGKKPEGIMIPTHLKVLTIEEKPFVYARKLLDDEIDCADDEVVCPHFNITNGNEQEYCC 461

  Fly   466 RGYCIDLLIELSKRINFTYDLALSPDGQFGHYILRNNTGAM--TLRKEWTGLIGELVNERADMIV 528
            :|||||||..|::|||||||||||||||||||.|:|:|..:  |::|||.|||||||.||||:||
Mosquito   462 KGYCIDLLKALAQRINFTYDLALSPDGQFGHYQLKNHTTGIGTTVKKEWNGLIGELVAERADLIV 526

  Fly   529 APLTINPERAEYIEFSKPFKYQGITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYL 593
            |||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   527 APLTINPERAEFIEFSKPFKYQGITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYL 591

  Fly   594 LDRFSPFGRFKLSHSDSNEEKALNLSSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMII 658
            |||||||||||||.:|..||.|||||||:||||||||||||||||||||||||||||||||||||
Mosquito   592 LDRFSPFGRFKLSTTDGTEEDALNLSSAIWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMII 656

  Fly   659 VASYTANLAAFLVLERPKTKLSGINDARLRNTMENLTCATVKGSSVDMYFRRQVELSNMYRTMEA 723
            |||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||
Mosquito   657 VASYTANLAAFLVLERPKTKLTGINDARLRNTMENLTCATVKGSSVDMYFRRQVELSNMYRTMEA 721

  Fly   724 NNYATAEQAIQDVKKGKLMAFIWDSSRLEYEASKDCELVTAGELFGRSGYGIGLQKGSPWTDAVT 788
            |||.||||||||||.||||||||||||||||||||||||||||||||||||:|||||||||||||
Mosquito   722 NNYDTAEQAIQDVKDGKLMAFIWDSSRLEYEASKDCELVTAGELFGRSGYGVGLQKGSPWTDAVT 786

  Fly   789 LAILEFHESGFMEKLDKQWIFHGHVQQNCELFEKTPNTLGLKNMAGVFILVGVGIAGGVGLIIIE 853
            ||||:||||||||.|||:|||||:||| ||.|||||||||||||||||||||.||.||:||||||
Mosquito   787 LAILDFHESGFMESLDKEWIFHGNVQQ-CEQFEKTPNTLGLKNMAGVFILVGAGIVGGIGLIIIE 850

  Fly   854 VIYKKHQVKKQKRLDIARHAADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGTISLAVDKRR 918
            |:|||||:||||:::||||||||||||||||||:||||||||||||||||. :....|...:|.|
Mosquito   851 VVYKKHQIKKQKKMEIARHAADKWRGTIEKRKTLRASLAMQRQYNVGLNSV-SKSVQSQNAEKSR 914

  Fly   919 YPRLGQ-RLGPERAWPGDAADVLRIRRPYELGNPGQSPKVMAANQPGMPMPMLGKTRPQQSVLPP 982
            ||.|.. ...||||||.|...::..:.                |..|...|            .|
Mosquito   915 YPILPPLPRTPERAWPKDKEYIVNRKN----------------NSSGAGKP------------SP 951

  Fly   983 RYSPGYTSDVSHLVV 997
            ||.|.|.:|||||:|
Mosquito   952 RYMPTYATDVSHLIV 966

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	37..405	CDD:380602	282/367 (77%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	347/402 (86%)
		CaM_bdg_C0	854..882	CDD:402271	22/27 (81%)
Nmdar1	XP_321646.4	None