Protein Alignment Nmdar1 and grin3b

DIOPT Version :9

• Sequence 1: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Sequence 2: XP_017952374.2
• Gene: grin3b / 100497172
• XenbaseID: XB-GENE-990106
• Length: 1005
• Species: Xenopus tropicalis
• Alignment Length: 896
• Identity: 229/896 - (25%)
• Similarity: 413/896 - (46%)
• Gaps: 123/896 - (13%)

  Fly    82 DKNPIKTVFNVCDKLIENRVYAVVVSHEQTSGDLSPAAVSYTSGFYSIPVIGISSRDAAFSDKNI 146
            |::|......:|..|:...: |.|::..|...:|  ..:.:.|.|..||.|.|..::
 Frog    81 DRSPASLTRWLCQVLVAQGI-AAVLAFPQAQEEL--LQLEFLSSFLEIPFISILEQE-------- 134

  Fly   147 HVSFLRTVPPYYHQ----------ADVWLEMLSHFAYTKVIII--HSSDTDGRAILGRFQTTSQT 199
            .:..|.|..|::.|          .|::..:|.:.::.:|.||  |..|:   |.:.|:.|::.|
 Frog   135 QIVPLATKNPFHLQMDTQSSVENLMDIFFSVLQNSSWEEVDIITCHPWDS---ASIQRYLTSNTT 196

  Fly   200 YYDDVDVRATVELIVEFEPKLES-----FTEHLIDMKTAQSRVYLMYASTEDAQVIFRDAGEYNM 259
            ...        ..|:...|..||     ..:|...||..|..:.|.......:.::||.|.:..:
 Frog   197 LVS--------RTILNIHPVDESALVPFLQQHFESMKNPQFPMLLYGCDARRSSLVFRVARDCGL 253

  Fly   260 TGEGHVWIV----TEQALFSNNTPDGVLGLQLEHAHSDKGHIRDSVYVLASAIKEMI---SNETI 317
            ......|::    ..:.:.:...|.|:|........:.:..|||:|.::..||...:   .:..:
 Frog   254 EAHEFHWMIGHPLNGEEMTTEGMPPGLLAYGEVSRPTMEKFIRDAVGLVTRAISAAVHVRPDLAL 318

  Fly   318 AEAPKDCGDSAV--NWESGKRLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINIREQQK---- 376
            .::..:|.|...  |..||..|.::|.:.:.:|:|||         ||...::|:.....:
 Frog   319 IQSMVNCNDKQTKQNESSGSYLSRFLANTSFSGQTGQ---------IYVSNNLIHTEHHYRIWSL 374

  Fly   377 -KHVVGKFSYDSMRAKMRMRINDSEIIWPGK-QRRKP-EGIMIPTHLRLLTIEEKPFVYVRRMGD 438
             :..:|..::.::....:.::...|.:|..: |:.:| .|....|.||::|:.|.|||:.|.: |
 Frog   375 VRDSLGDPTWVTVGGWRQGKMEVEEGLWQSRIQQWEPAPGGFARTKLRVVTLVEHPFVFTREV-D 438

  Fly   439 DEFRCEPDERPC--PLFNNS---DATANEF-------------CCRGYCIDLLIELSKRINFTYD 485
            .:..| |..:.|  |..|||   |....|.             ||.|||||||.:||:.:.|.::
 Frog   439 ADGSC-PAGQMCLDPRTNNSAVLDVLFEELNSPNGSVPLEYKTCCYGYCIDLLEKLSEDLRFDFE 502

  Fly   486 LALSPDGQFGHYILRNNTGAMTLRK--EWTGLIGELVNERADMIVAPLTINPERAEYIEFSKPFK 548
            |.:..||::|            .||  .||||:|:|::..|.|.|...:||..|:..|:|:.||.
 Frog   503 LYIVGDGKYG------------ARKGDRWTGLVGDLLSGAAHMAVTSFSINSARSTVIDFTSPFY 555

  Fly   549 YQGITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSHSDSNEE 613
            ...:.||.:....:|.:.:|:.|...::|:.:.|::|:.||.|...:..||||   ::....|..
 Frog   556 STSLGILVRMRDTASPIGAFMWPLHWSMWVGIFVALHITALFLTFYEWKSPFG---MTPHGRNRT 617

  Fly   614 KALNLSSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTK 678
            |..:.|||:...:.:|....:...||:..:.|||..:||.|.:::::||||||||.:|.::....
 Frog   618 KIFSYSSALNLCYAILFGRTVSSKTPKCCTGRVLMNLWAIFCLLVLSSYTANLAAVMVGDKTFEA 682

  Fly   679 LSGINDARLRNTMENLTCATVKGSSVDMYFRRQVELSNMYRTMEANNYATAEQAIQDVKKG--KL 741
            ||||:|.:|.:..:.....||..||.:.|.::  ....|:..|...:.......:..:|..  .|
 Frog   683 LSGIHDPKLHHPSQGFRFGTVWESSAEQYIKK--SFPEMHNYMRKFSVPATSDGVHLLKTDPPTL 745

  Fly   742 MAFIWDSSRLEYEAS--KDCELVTAGELFGRSGYGIGLQKGSPWTDAVTLAILEFHESGFMEKLD 804
            .|||.|.:.|:||.|  .||:|:|.|:.|...||||||.:.||.|..::..|..:..||||:.|.
 Frog   746 NAFIMDKALLDYEVSIDSDCKLLTIGKPFAIEGYGIGLPQNSPLTSNISEFISRYKSSGFMDTLH 810

  Fly   805 KQWIFHGHVQQNCELFEKTPN-TLGLKNMAGVFILVGVGIAGGVGLIIIE-VIYKKH----QVKK 863
            .:|  :..|.....::..|.. .:|:.:.:|:|:|:.:|..|.:...::| |:|  |    ::::
 Frog   811 DKW--YKMVPCGKRVYAVTETLQMGIYHFSGLFVLLCIGFCGSLLTSLMERVVY--HLILPRIRR 871

  Fly   864 QKRLDIARHAADK----WRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGTI 910
            ::|.....|.:.|    ...|.|.:..:  |..:.::.|:..::|.||.::
 Frog   872 RRRFKYWLHTSQKIHRALNMTCEDQDAL--SPKLNKRCNLQKDATGAPQSV 920

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	12..405	CDD:107374	68/353 (19%)
		ANF_receptor	58..371	CDD:279440	65/314 (21%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	137/424 (32%)
		HisJ	451..>558	CDD:223904	42/124 (34%)
		Periplasmic_Binding_Protein_Type_2	<516..651	CDD:304360	38/134 (28%)
		Lig_chan	575..838	CDD:278489	83/267 (31%)
		CaM_bdg_C0	854..882	CDD:287524	7/35 (20%)
grin3b	XP_017952374.2	PBP1_iGluR_NMDA_NR3	29..402	CDD:380600	67/351 (19%)
		PBP2_iGluR_NMDA_Nr3	418..814	CDD:270438	136/416 (33%)
		Lig_chan	582..848	CDD:395014	84/272 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910