Protein Alignment Nmdar1 and si:ch211-264f5.8

DIOPT Version :10

• Sequence 1: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Sequence 2: XP_017207885.1
• Gene: si:ch211-264f5.8 / 100331381
• ZFINID: ZDB-GENE-081104-209
• Length: 1063
• Species: Danio rerio
• Alignment Length: 1110
• Identity: 269/1110 - (24%)
• Similarity: 445/1110 - (40%)
• Gaps: 278/1110 - (25%)

  Fly    12 LFGLAIVLLVAP--------IDAAQRHTASDNPSTYNIGGVLSNSDSEEHFSTTIK--------- 59
            |..|.::|.:||        :.|.:.....|:.|....|..|:.:.:.|:.::.::
Zfish    13 LLFLVLLLTMAPSSHSQVPALSAVRMAAILDDQSACGRGERLALALARENINSLMEGPARARVEV 77

  Fly    60 ---HLNFDQQYVPRKVTYYDKTIRMDKNPIKTVFNVCDKLIENRVYAVVVSHEQTSGDLSPAAVS 121
               .|..|.||                   :|...:|..|.:..|..:..:....||    :.||
Zfish    78 DIFELQRDSQY-------------------ETTDTMCQILPKGVVSVIGPASSPASG----STVS 119

  Fly   122 YTSGFYSIPVIGISSRDAAFSDKNIHVSFLR--TVPPYYHQADVWL---EMLSHFAY-TKVIIIH 180
            :..|...||.|.|...:..      .:.:||  :|..|....|:.|   .:|..|.| |..:|..
Zfish   120 HICGEKEIPHIKIGPEETP------RLPYLRFASVTLYPSNEDLSLAIGAILRSFGYPTASLICA 178

  Fly   181 SSDTDGR--AILGRFQTTSQTYYDDVDVRATVELIVEFEPKLESFTEHLIDMKTAQSRVYLMYAS 243
            .::...|  .::..|..:.:|    :.||...|   ..:|     |..|.:::..:....::.|:
Zfish   179 KAECLLRLEELVRHFLISRET----LSVRMLDE---NLDP-----TPLLKEIRDDKVATIIIDAN 231

  Fly   244 TEDAQVIFRDAGEYNMTGEGHVWIVTEQALFSNNTPDGVLGLQLEHAHSDKGHI----------- 297
            ...:.:|.:.|.|..||...:.:|:|        |.|..| |:|:...:|:.:|
Zfish   232 ASVSILILKKASELGMTSAFYKYILT--------TMDFPL-LRLDDVVNDQSNIVGFSMLNNSHP 287

  Fly   298 --------------------------------RDSVYVLASAIKEMISNETIAEAPKDCGDSAVN 330
                                            .|:|:|:..|::|:..::.|...|..|..|.:
Zfish   288 FYLEFIRSLNLSWREGCDLSPYPGPALSSALMFDAVHVVVGAVRELNRSQEIGVKPLSCTSSLI- 351

  Fly   331 WESGKRLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINIREQQK---KHVVGKFSYDSMRA-K 391
            |:.|..|..||:.....|.||:|.|:..|.|  ..| .:.|.|:.|   |.:...:|.:::.. .
Zfish   352 WQHGTSLMNYLRMVEYDGLTGRVEFNSKGQR--TNY-TLRILEKFKGGHKEIGVWYSNNTLAMNS 413

  Fly   392 MRMRINDSEIIWPGKQRRKPEGIMIPTHLRLLTIEEKPFVYVRRMGDDEFRCEPDERPCPLFNNS 456
            ..:.||.||             .:....|.:.||.|.|:|..:....|             |..|
Zfish   414 TSLDINTSE-------------TLANKTLTVTTILENPYVMRKENYQD-------------FQGS 452

  Fly   457 DATANEFCCRGYCIDLLIELSKRINFTYDLALSPDGQFGHYILRNNTGAMTLRKEWTGLIGELVN 521
            |.      ..|:|:|:|.||:..:.|::.:.|..||.:         ||......|||::|||:|
Zfish   453 DQ------YEGFCVDMLRELADILKFSFRIKLVDDGLY---------GAPEPNGSWTGMVGELIN 502

  Fly   522 ERADMIVAPLTINPERAEYIEFSKPFKYQGITIL-----EKKPSRSSTLVSFLQPFSNTLWILVM 581
            .:||:.||..||..||.:.|:|||||...||:||     .:||.    ..|||.|||..:|:.::
Zfish   503 RKADLAVAGFTITSEREKVIDFSKPFMNLGISILYRVHIGRKPG----YFSFLDPFSPAVWLFML 563

  Fly   582 VSVHVVALVLYLLDRFSPFGRFK-----LSHSDSNEEKALNLSSAVWFAWGVLLNSGIGEGTPRS 641
            ::...|:.||:|..|.||:..:.     ....|..|.: ..|.:::||..|..:..| .|..||:
Zfish   564 LAYLAVSCVLFLAARLSPYEWYNPFPCWRERRDLLENQ-YTLGNSLWFPIGGFMQQG-SEIMPRA 626

  Fly   642 FSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTKLSGINDARLRNTMENLTCATVKGSSVDM 706
            .|.|.:..||..|.:||::||||||||||.::|.:..:....|..   ...|:...|::|.|...
Zfish   627 LSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIESAEDLA---DQTNIQYGTIQGGSTMT 688

  Fly   707 YFRRQVELSNMYRTMEAN-NY----------ATAEQAIQDVKKGKLMAFIWDSSRLEYEASKDCE 760
            :|     :::.|:|.:.. ||          .:.|:.|..|...| .||:.:|:..||....:|.
Zfish   689 FF-----MNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSK-YAFLLESTMNEYHRRLNCN 747

  Fly   761 LVTAGELFGRSGYGIGLQKGSPWTDAVTLAILEFHESGFMEKLDKQWIFHGHVQQNCELFEKTPN 825
            |...|.|....|||||:..|||:.|.:||.||:..|:..:|.|.::|...|    .| |.|:...
Zfish   748 LTQIGGLLDTKGYGIGMPLGSPFRDEITLGILQLQENNRLEILKRRWWEGG----KC-LKEEDHR 807

  Fly   826 T--LGLKNMAGVFILVGVGIAGGVGLIIIEVIY------------------KKHQVKKQKRLDIA 870
            .  ||:.|:.|:|:::..|:...|.:.|:|.::                  :.|   :..|:.:.
Zfish   808 AKGLGMDNIGGIFVVLICGLIIAVFVAIMEFVWSTRRSAETDEVRPHPCPVRNH---RHARVSVC 869

  Fly   871 RHAADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHAPGTISLAVDKRRYPRLGQRLGPERAWPGD 935
            :....::|..|..:|..|  |..:|.::       :.|.:       |:|   .||      |..
Zfish   870 QEMMTEFRNVISCKKNSR--LRRRRAFS-------SQGVL-------RHP---ARL------PLG 909

  Fly   936 AADVLRIRRPYEL--------------GNPGQSPKVMAANQ-PG----MPMPMLGKTRPQQSVLP 981
            |:..:|:.|...|              |.||..|...||.. ||    :..|:.........||.
Zfish   910 ASRPIRLVREMRLSNGKLYSGTGTVPSGTPGPGPAAGAAEMGPGPQRLLEDPLNASVPSSAPVLL 974

  Fly   982 PRYSP 986
            |..:|
Zfish   975 PTAAP 979

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	37..405	CDD:380602	87/434 (20%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	132/421 (31%)
		CaM_bdg_C0	854..882	CDD:402271	3/45 (7%)
si:ch211-264f5.8	XP_017207885.1	PBP1_iGluR_Kainate_KA1_2	35..413	CDD:380616	85/431 (20%)
		Periplasmic_Binding_Protein_Type_2	426..796	CDD:473866	131/412 (32%)