|
Fly 1 MGDNIIGSASFLHLGDIVSLYAEGSVCGFLSTLGLVDDRTVVCPEAGDLSCPPKKFRDCLIKICP 65
|.|: ::||||:||||||||||:|.||:|||||||||.||.|.:|||..|||||||||.|:.|
Zfish 1 MSDS---ASSFLHIGDIVSLYAEGTVNGFISTLGLVDDRCVVEPASGDLENPPKKFRDCLFKVYP 62
Fly 66 MNRYSAQKQFWKA--AKQSASSNTDPNLLKRLHHAAEIEKKQNETENKKLLGTSIQYGRAVVQLL 128
||||||||||||| ||.......|..||::|.|||.:|:|||:.||||:.|..::|| :|:|||
Zfish 63 MNRYSAQKQFWKAKQAKHEKDKIGDMVLLQKLQHAANLEQKQNDAENKKVHGDVVKYG-SVIQLL 126
Fly 129 HLKSNKYLTVNKRLPSLLEKNAMRVYLDANGNEGSWFYIKPFYKLRSIGDYVVVGDKVILSPVNA 193
|:|||||||||||||:|||||||||.||..||||||.:|:||:|||:.||.|||||||||:||||
Zfish 127 HMKSNKYLTVNKRLPALLEKNAMRVTLDGTGNEGSWLFIQPFWKLRANGDNVVVGDKVILNPVNA 191
Fly 194 DQQNLHVAANYELPDNPGCKEVNVLNSSTSWKISLFMEHKENQEHILKGGDVVRLFHAEQEKFLT 258
.|. || |::|||||:.||||:|.:||:|||||||||...::::.:|||||||||||||||||||
Zfish 192 GQP-LH-ASSYELPDHSGCKEINSVNSNTSWKISLFMMFSDHKDEVLKGGDVVRLFHAEQEKFLT 254
Fly 259 MDEYKKQYHVFLRTTGRTSATAATSSKALWEIEVVQHDSCRGGAGDWNSLYRFKHLATGHYLAAE 323
.||||.:.|||||||.|.|||:||||.||||:|||.||.||||||.|||||||||||||:|||||
Zfish 255 CDEYKSKLHVFLRTTLRQSATSATSSNALWEVEVVHHDPCRGGAGHWNSLYRFKHLATGNYLAAE 319
Fly 324 AEIDVSAGAMSATSASGHDLHLGDCSKDSGLSCSTMNSTINDKPKGKQYRLVSVPYSADIASVFV 388
.. .|:..:..|...|| |.:..::.::.| |:||:||:..||||:|.
Zfish 320 EN-------------PGYKENSNDIEVDS----SRIKRSLGERIK---YKLVAVPHGNDIASLFE 364
Fly 389 LDATTMARPDSLVPQSSYVRLQHICSNTWVHATSIPIDADDDKPVMSMVCCSPIKEDKEAFALIP 453
||.||:.:.||.||::||||.:|:|:|||:.:|:||||.|:::|:..|:...|.||||||||::.
Zfish 365 LDPTTLQKTDSFVPRNSYVRFRHLCTNTWIQSTNIPIDIDEERPIRLMLGTCPTKEDKEAFAIVS 429
Fly 454 VSPVEVRDLDFANDACKVLATVTSKLDNGSISINERRALISLLQDIVYFIAGMENEQNKTKALEF 518
|..:|:|||||||||..:|:||..|...|.:|.|:||..|.||:|:|:|:....| |...|||.
Zfish 430 VPVMEIRDLDFANDASLMLSTVVEKFKYGFLSPNDRRYAIKLLEDVVFFVVDQLN--NGQPALEV 492
Fly 519 TIKNPIRDRQKLLREQYILKQLFKILQGPFQQHTAGDGPFLRLDELSDPKNSPYKNIFRLCYRIL 583
::..|.|:||||:|||.||||:|.|::.||::. ..|.|.|.|:||||.|...|:.:.|||||:|
Zfish 493 SMNKPNRERQKLMREQNILKQIFGIIKAPFKER-GDDPPLLTLEELSDQKYLLYQYMLRLCYRVL 556
Fly 584 RLSQQDYRKNQEYIAKHFGLMQKQIGYDILAEDTITALLHNNRKLLEKHITAAEIETFVGLVRKN 648
|.||:|||||||||||.||:||.||||||||||||||||||||||||||||..|:||||.|||||
Zfish 557 RHSQEDYRKNQEYIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRKN 621
Fly 649 MHNWDSRFLDYLSDLCVSNRKAIAVTQELICKSVLSDKNKDILIETQVKALRTGSGPVRCYKGNS 713
. :.|||||||||||||..||.||||||||.||:.||:|||::|:.:|.:
Zfish 622 R---EPRFLDYLSDLCVSNNVAIPVTQELICKCVLNAKNQDILMKTERRAAK------------- 670
Fly 714 EDVCLATLAEDAGDDEDRSDVQSTSTTTTWDSASLNEDDGTPSTGDKYEIHLKWT---GQPTSRS 775
:.|.|| :.....||:.|:.|.|: .:...:|
Zfish 671 -------------------ESQHTS-------------EYLEEFGDEDEVWLIWSEKENENHEKS 703
Fly 776 MADLA--SCDGGELEAAILNYYRHQLNLFSNMCLNRQYLALNELSPRLDIDLILKCMSDETMPYE 838
:..|| :..|...:..:|.|||:||.||:.||.:|||||::.:|.:|||:||..||.|||:|::
Zfish 704 IRQLAQEARQGNVHDENVLTYYRYQLKLFARMCFDRQYLAIDVISKQLDIELISLCMMDETLPFD 768
Fly 839 LRASFCRLMLHLHVDRDPQEPVTPVKYARLWSEIPSKMSIQDYDGKNQQPDQNKQACRAKFNTTI 903
|||||||||||.||||||||.|||:|:||||:|||:.:||:|||........|| :.||..|:
Zfish 769 LRASFCRLMLHAHVDRDPQELVTPIKFARLWTEIPTSISIKDYDSHLDYSRDNK---KNKFANTM 830
Fly 904 AFVENYLCNVATKVWLFTDQEQNKLTFEVVKLARDLIYFGFYSFSDLLRLTKTLLSILDCVSDTS 968
||:|.||.||......|.::|:||||:|||.|||.|||||||||.:|||||:|||.|:||....:
Zfish 831 AFMEEYLNNVLIDDLPFANEEKNKLTYEVVSLARHLIYFGFYSFFELLRLTRTLLGIIDCTPSNA 895
Fly 969 SGEFASTDIDSVEEETNAEAEG-GVLRSIGDINTVMTSLALGSVGQAIAAPTISLQQRKSVSQLM 1032
|:....|.:..| .|.|||..:..:|:::.|.......:|| .|...||:.
Zfish 896 ----------SINPLFNDDGSGKNVRRSIHGMGQMMSTMVLNRKPSLFSAP-----GRTGDSQVG 945
Fly 1033 KEYPL------VMDTKLKIIEILQFILDVRLDYRISCLLSIFKREFDESEVAASAASNEASQQQS 1091
.:..: ||||||||:|||||||.||||||:|.|||:||:||
Zfish 946 SKDSIDTQDITVMDTKLKILEILQFILSVRLDYRLSFLLSVFKKEF------------------- 991
Fly 1092 QQQEPQTPGSSNETDPLDSAESVAAGAAAAAATTARQKNIDLESIGVQAEGIFDCERSDAANLDL 1156
.:..|::.|: |...|..:.:|:|:.||.|||.:|...:.::. |::
Zfish 992 -----------VDVYPMEDAD--------ATHHTEHEASINLQHIGEQAEAMFGIGKGNSI-LEV 1036
Fly 1157 DGQGGRTFLRVLLHLIMHDYAPLVSGALHLLFRHFSQRQEVLQAFRQVQLLVSDSDVESYKQIKS 1221
|.:|||.|||||:|||||||.|||||||.|||:|||||||||..|:|||||:|..||::||.||.
Zfish 1037 DDEGGRMFLRVLIHLIMHDYPPLVSGALQLLFKHFSQRQEVLHTFKQVQLLISTQDVDNYKHIKR 1101
Fly 1222 DLDILRQSVEKSELWVYKAKATDELGATDAGG----DAVSLEYNA---ALSQEQRNE-YRKVKEI 1278
|||:||..||||||||.|..::...|..|... :|||.|..| ..:.|:.|| |:.||||
Zfish 1102 DLDLLRTMVEKSELWVIKKSSSGGDGKKDKKDKKEPEAVSPEEEADSKKQTTEKSNESYQNVKEI 1166
Fly 1279 LIRMNKFCVTASGPGSVVKPRKHEQRLLRNVGVHTVVLDLLQNPYDEKDDELMKELMCLAHEFLQ 1343
|.|:||.| :|| ..|.:||||:|:|.|.|:|||||..||..|.::: |::...|.|||
Zfish 1167 LERLNKMC--SSG------VFKKQQRLLKNMGAHKVMLDLLQISYDRNDTKML-EIIKYTHLFLQ 1222
Fly 1344 NFCLGNQQNQVLLHNHLDLFLNPGILEAKTVCAIFKDNLALCNEVTDKVVQHFVHCIEIHGRHVA 1408
.||.||.:||.|||.||:|||.|.:|||:|:..||.:|..||:|:::.|:.||:||:...|||:.
Zfish 1223 KFCTGNLENQALLHKHLNLFLTPRLLEAETMQQIFSNNFQLCSEISESVLHHFIHCLATQGRHIQ 1287
Fly 1409 YLQFLQTVVRAENQFIRRCQDMVMQELINSGEDVLVFYNDKGSFNHFVQMMQQQMLRMEKLSDDS 1473
||.||.|:::||.:::::||||:|.||.::|:||:|.|.|..|||..|::|.|. .|.:.|||
Zfish 1288 YLNFLHTIIKAEGKYVKKCQDMIMTELTSAGDDVVVLYTDDTSFNTMVELMTQS---REGVKDDS 1349
Fly 1474 PLKYHVELVKLLACCTMGKNVYTEIKCNNLLSLDDIVTIICHPLCMPEVKEAYVDFLNHCYIDTE 1538
||:||:.||:|||.|..||||||||||.:||.|:::|.:|.|..|:.|||.|||:|:||||:|||
Zfish 1350 PLRYHISLVELLAACAEGKNVYTEIKCTSLLPLEEMVKVITHEDCITEVKIAYVNFVNHCYVDTE 1414
Fly 1539 VEMKEIYASGHMWSLFEKSFLVDINQLITN-PAAASNKTLQAYVLNGVTNLLGSFFASPFSDQSA 1602
|||||||.|.|:|.||| :|.||:.::.:| ....|:..|:.||:..|.:.:.:||:||||:.|.
Zfish 1415 VEMKEIYTSNHIWKLFE-NFTVDMARVCSNREKRMSDPVLEKYVIQVVLDTVTAFFSSPFSENST 1478
Fly 1603 IVQSRQLIFVQLLQAAHRITQCRWLSLGDRFNVENCIRTLTESAKMRSIALPPELEQQVATMSSK 1667
..::......||||:..|:..|.||....:..||:|||||..:.|.|||.||.|||..|..|.|.
Zfish 1479 STEAHHTTVKQLLQSTMRLLDCPWLQPQQKVQVESCIRTLAVTTKSRSIPLPVELEAHVNMMLSH 1543
Fly 1668 TAMLTRQTTKWLLASKQPKYEAQQAASLMRWD-RSIIEGLQDIVSLLEDQLKPVVEAELSLLVDI 1731
:..||...:.. ::|......:.||....|| ::|||.||||::.||:::.|:|.||||:|||:
Zfish 1544 SNSLTLSRSSH--SNKSMSRLTRPAAPTNPWDYKNIIEKLQDIINTLEERVMPLVNAELSVLVDV 1606
Fly 1732 LYRSELLFPAGTEARKRCESGGFIRKLIKHTEKLLEEKEERMCVKVLRTLREMMAIDVNYGEKGD 1796
|::.||||..||:||.||||||||.|||:|| |.|...:|::|:||||||:||:..::::.|||.
Zfish 1607 LHQPELLFLEGTDARSRCESGGFISKLIQHT-KALMNSDEKLCIKVLRTLQEMLIRELDFDEKGF 1670
Fly 1797 ALRQTLLLRYFQTKSTPRLPEDEVPLLAAPLMDPAKQN---HLVTHGPGAKYLQRAGKTLHEMQN 1858
|||:.||..|.... |:| .||.|..||:. :|...|:..:|.
Zfish 1671 ALRKVLLQNYLYNN---------------------KKNIKAELVEHAGGAEG-ERDWLTVAALQC 1713
Fly 1859 HLDREGASDLVVELVIKSVHSPNIFVEAVELGIALLEGGNPIIQKGMFQKFLSDDLNQAFFKVFF 1923
.||:||.:.|..:| |.|..:..||.|:::|.|.||||||..||...::..:.|:.::.||||..
Zfish 1714 RLDKEGGTKLFTDL-ITSTKNEKIFQESIQLAICLLEGGNTEIQNSFYKLMMGDNKSEKFFKVLN 1777
Fly 1924 EKMKDAQQEIKSTVTVNTTDIAAKAHEHKQDTNLELDKIARKHGLKSNGVVITEELKRELHNAGL 1988
::||:||.:|||||:||..:::.|| |.|.:||.. |:.|.|
Zfish 1778 DRMKNAQLDIKSTVSVNVGEMSNKA---KDDKDLETG------GVSSFG---------------- 1817
Fly 1989 ATARAYGNARNIHSGEESSAISVNSPLEDILAEKLEKHKDSRDQRNQLSNKVLVMQPILRFLQLL 2053
:.|...:.::...::...|.:|:|||||||||
Zfish 1818 ---------------------------------QPEPQPEQQEVETEMGPSVTIMKPILRFLQLL 1849
Fly 2054 CENHNPDMQNLLRNQNNKTNNNLVSETLMFLDCICGSTTGGLGLLGLYINEHNVALINQTLEALT 2118
|||||.|:||.||.||||||.|||||||.|||.:|||||||||||||||||:||.||.||||.||
Zfish 1850 CENHNQDLQNFLRIQNNKTNYNLVSETLQFLDIMCGSTTGGLGLLGLYINENNVELITQTLETLT 1914
Fly 2119 EYCQGPCHENQNCIATHESNGLDIITALILNNINPLGENRMDLVLELKNNASKLLLAIMESRGDS 2183
|||||||.|||.||.:||.||:|||||||||:|:||...||:|||:||:||||||||:||||.||
Zfish 1915 EYCQGPCQENQTCIVSHECNGIDIITALILNDISPLCRYRMELVLQLKDNASKLLLALMESRHDS 1979
Fly 2184 ENAERILYNMNPKQLVEVACKAYHQEELIDEQDDGDEPDAGSDDDDATVSPREVGHNIYILCHQL 2248
|||||||:|:.|::|||:..|||.|| .|..:|: |||||||||||||..||
Zfish 1980 ENAERILFNLRPRELVELIKKAYLQE---GECKEGE------------VSPREVGHNIYILALQL 2029
Fly 2249 AQHNKELAGLLK-----ASEDPQSASF--------DAKTSQALMYYATHTAQIEIVRNDRTLEQI 2300
|:|||.|..||| ..|:.:|.|. :.:....|.:|...||||||||.||::|||
Zfish 2030 ARHNKVLLTLLKPVKKIKEEEEESISSMLNLNKQQEEEKEDPLEHYDRQTAQIEIVREDRSMEQI 2094
Fly 2301 VFPIPEICEYLTTDTKIKILNTAERDDQGSKVADFFDKAEEMFNEMKWQKKLRSQPLLFWISSYM 2365
|||:..|||:||.::|.::..|.|:|:|||||.:||::...:.|||:|||||||.|:|:|.|..|
Zfish 2095 VFPVHPICEFLTEESKFRVFTTTEQDEQGSKVTNFFEQTSFLHNEMEWQKKLRSMPVLYWFSRRM 2159
Fly 2366 SLWSNILFNCVVVINMIVAFFYPFDNTVPELSSH-----ISLL---FWIITIFSLVIVLALPRES 2422
|||..|.||..|.||:|:|.|||.| |.| .||| ||... .|.::..|.:..
Zfish 2160 SLWGTISFNLAVFINLIIALFYPHD------SGHSGSIDSSLLLMGFWCFA--GLAVLGLLFKRY 2216
Fly 2423 GIRTFIGSVILRFIFLLGPESTLCLLGVVTVTLKSVHIVSIMGNKGTLEKQLIKIITDFQLLYHC 2487
|.::...::.||.|:..|...||.|||.:.:..|.|::||.:||.||.......::.|.:.|||.
Zfish 2217 GFQSLTVAITLRCIYHFGIGPTLLLLGALNLINKIVYLVSFVGNNGTFIMGYKAMVMDVEFLYHV 2281
Fly 2488 IYIAFCFCGLIFHPFFYSLLLFDVVYREETLVNVIRSVTRNGRSIVLTAVLALILVYLFSIIGYM 2552
.|:.....||..|.||||:||||::||||||.|||:|||||||||:||||||:||||||||:|::
Zfish 2282 AYVLTSSLGLFVHEFFYSILLFDLIYREETLFNVIKSVTRNGRSILLTAVLAIILVYLFSIVGFL 2346
Fly 2553 FFKDDFLVSVDFEEQDNAPPPSVPLTLSVPVSGD------SCSAPDDLGNCQAAKEVAPPSAGGG 2611
|.::||::.||. |:.|..|| |||: |..:|.....:..|:....
Zfish 2347 FLRNDFIMEVDH--------------LASPAPGDTESFMSSCSS--DGIDCTEETGLLAPAEEDE 2395
Fly 2612 EVKERSCDSLVMCIVTTLNQGLRNGGGIGDILRAPSSKEGLFVARVIYDLLFFFIVIIIVLNLIF 2676
:..||:||:|:|||:|.||.|||||||:||:||.||..|.||.|||:|||||:||||||||||||
Zfish 2396 DNTERACDTLLMCIITVLNHGLRNGGGVGDVLRKPSKNEPLFPARVVYDLLFYFIVIIIVLNLIF 2460
Fly 2677 GVIIDTFADLRSEKQQKEAILKTTCFICSLNRSAFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVK 2741
|||||||||||||||:||.:||||||||.|.|..|||||||||||||.|||:|:|||||||::.|
Zfish 2461 GVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKLEHNIWNYLYFIVLIREK 2525
Fly 2742 DPTEFTGPESYVYAMVKAGILEWFPRLRAMSLAAVDADGEQIELRSMQAQLLDTQLLIKNLSTQL 2806
:.|::|||||||..|:|...|:||||::||||...|.||||.|:|::|.:|..|..::..|::||
Zfish 2526 NKTDYTGPESYVALMIKNKNLDWFPRMQAMSLVVTDGDGEQNEMRNLQDRLSSTMKVVTQLTSQL 2590
Fly 2807 HELKDHMTEQRKQKQRLGLLNTTANS 2832
.|||:.||||||::||:|.::..:.|
Zfish 2591 TELKEQMTEQRKRRQRMGFVDVQSGS 2616
| 
