|
Fly 9 ASFLHLGDIVSLYAEGSVCGFLSTLGLVDDRTVVCPEAGDLSCPPKKFRDCLIKICPMNRYSAQK 73
:||||:||:.|||||||..||:|||||||||.||.|:||||:.|||||||||.::||||||||||
Zfish 6 SSFLHIGDVCSLYAEGSTSGFISTLGLVDDRCVVQPDAGDLNNPPKKFRDCLFRLCPMNRYSAQK 70
Fly 74 QFWKAAKQSASSNTDPNLLKRLHHAAEIEKKQNETENKKLLGTSIQYGRAVVQLLHLKSNKYLTV 138
|||||||...:|.||..||.:|||||::|||||::||||||||.||||. |:|||||||||||||
Zfish 71 QFWKAAKPGGTSTTDTVLLNKLHHAADLEKKQNDSENKKLLGTVIQYGN-VIQLLHLKSNKYLTV 134
Fly 139 NKRLPSLLEKNAMRVYLDANGNEGSWFYIKPFYKLRSIGDYVVVGDKVILSPVNADQQNLHVAAN 203
|||||:|||||||||.|||.|||||||||:||||||||||.||:||||:|:||||.|. || |::
Zfish 135 NKRLPALLEKNAMRVTLDAAGNEGSWFYIQPFYKLRSIGDNVVIGDKVVLNPVNAGQP-LH-ASS 197
Fly 204 YELPDNPGCKEVNVLNSSTSWKISLFMEHKENQEHILKGGDVVRLFHAEQEKFLTMDEYKKQYHV 268
::|.|||||.|||.:|.:|||||.|||:..:|||.:|||||||||||||||||||.||::|:.:|
Zfish 198 HQLVDNPGCNEVNSVNCTTSWKIVLFMKWSDNQEIVLKGGDVVRLFHAEQEKFLTCDEHRKKQYV 262
Fly 269 FLRTTGRTSATAATSSKALWEIEVVQHDSCRGGAGDWNSLYRFKHLATGHYLAAEAEIDVSAGAM 333
|||||||.|||:|||||||||:||||||.||||||.||||:||||||||||||||...|.....:
Zfish 263 FLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVNPDYEEECL 327
Fly 334 SATSA--SGHDLHLGDCSKDSGLSCSTMNSTINDKPKGK-QYRLVSVPYSADIASVFVLDATTMA 395
.:.|: |.|:: :.....| |:.| .|.|||||...||:|:|.||.||:.
Zfish 328 ESRSSMDSEHEV----------IRARARN------PQDKVMYTLVSVPDGNDISSIFELDPTTLR 376
Fly 396 RPDSLVPQSSYVRLQHICSNTWVHATSIPIDADDDKPVMSMVCCSPIKEDKEAFALIPVSPVEVR 460
..|||||::|||||:|:|:|||||:|:.|||.:::||||..:..||:||||||||::||||.|||
Zfish 377 GGDSLVPRNSYVRLRHLCTNTWVHSTNQPIDKEEEKPVMLRIGTSPLKEDKEAFAIVPVSPAEVR 441
Fly 461 DLDFANDACKVLATVTSKLDNGSISINERRALISLLQDIVYFIAGMENEQNKTKALEFTIKNPIR 525
||||||||.||||::.:||:.|:|:.||||::..||:|:|||:..:.: :....||.|:..|.|
Zfish 442 DLDFANDASKVLASIAAKLEKGTITQNERRSVTKLLEDLVYFVVDIPS--SAQDVLEITVNKPNR 504
Fly 526 DRQKLLREQYILKQLFKILQGPFQQHTAGDGPFLRLDELSDPKNSPYKNIFRLCYRILRLSQQDY 590
:||||:|||.||||:||:||.||.. :||||.|||:||:|.:::|:::|.|||||:||.|||||
Zfish 505 ERQKLMREQNILKQIFKLLQAPFTD--SGDGPMLRLEELADQRHAPFRHICRLCYRVLRYSQQDY 567
Fly 591 RKNQEYIAKHFGLMQKQIGYDILAEDTITALLHNNRKLLEKHITAAEIETFVGLVRKNMHNWDSR 655
|||||||||.|..||||||||:||||||||||||||||||||||||||:|||.|||||. :.|
Zfish 568 RKNQEYIAKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNR---EPR 629
Fly 656 FLDYLSDLCVSNRKAIAVTQELICKSVLSDKNKDILIETQVKALRTGSGPVRCYKGNSEDVCLAT 720
|||||||||||..|:|.|||||||.:||...|.||||||::...|. :|....
Zfish 630 FLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETKLVLSRF-------------EVAGTV 681
Fly 721 LAEDAGDDEDRSDVQSTSTTTTWDSASLNEDDGTPSTGDKYEIHLKWT---GQPTSRSMADLA-- 780
|.|.|.::|: |:.|:.|.|. |:..|:|:.:||
Zfish 682 LGEGAEEEEE----------------------------DEEEVWLFWKDSGGEVKSKSIRELAQD 718
Fly 781 SCDGGELEAAILNYYRHQLNLFSNMCLNRQYLALNELSPRLDIDLILKCMSDETMPYELRASFCR 845
:.||...:..::||||:|||||:.|||:|||||:|::|.:||:||||:|||||.:|::|||||||
Zfish 719 AKDGHTEDQEVINYYRYQLNLFARMCLDRQYLAINKISAQLDVDLILRCMSDEDLPFDLRASFCR 783
Fly 846 LMLHLHVDRDPQEPVTPVKYARLWSEIPSKMSIQDYDGKNQQPDQNKQACRAKFNTTIAFVENYL 910
:|||:||||||||.|||||||||||||||::||.|||......|:.|: :|:.|:.||||||
Zfish 784 MMLHMHVDRDPQEQVTPVKYARLWSEIPSQISIDDYDNDGTSSDEVKE----RFSQTMEFVENYL 844
Fly 911 CNVATKVWLFTDQEQNKLTFEVVKLARDLIYFGFYSFSDLLRLTKTLLSILDCVSDTSSGEFAST 975
.:|..:.:.|:|:|:||||||||.|||:|||||||:|||||||||.||:||||| ..||
Zfish 845 RDVVCQSFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCV-------HIST 902
Fly 976 DIDSVEEETNAEAEGGVLRSIGDINTVMTSLALGSVGQAIAAPTISLQQR---KSVSQLMKEYPL 1037
.. .::.:........|:|||..:..:||.:.|.. |..:.|.:.:...| |:.|:..|:..|
Zfish 903 PF-HIKLDREPGKGSNVMRSIHGVGELMTQVVLRG-GGFLPASSHNPPDRDEVKAQSEPQKQDIL 965
Fly 1038 VMDTKLKIIEILQFILDVRLDYRISCLLSIFKREFDESEVAASAASNEASQQQSQQQEPQTPGSS 1102
||||||||||||||||:|||||||||||.|||.||||| :.|......|::|.|
Zfish 966 VMDTKLKIIEILQFILNVRLDYRISCLLCIFKTEFDES-----------NSQSEPSLSPESPAS- 1018
Fly 1103 NETDPLDSAESVAAGAAAAAATTARQKNIDLESIGVQAEGIFDCERSDAANLDLDGQGGRTFLRV 1167
..|| :|.|.|..||||||.....:...||||..||||||||
Zfish 1019 ------------VQGA------------LDFEHIEEQAEGIFGGSSEENTPLDLDDHGGRTFLRV 1059
Fly 1168 LLHLIMHDYAPLVSGALHLLFRHFSQRQEVLQAFRQVQLLVSDSDVESYKQIKSDLDILRQSVEK 1232
||||.||||.||||.|||||||||||||||||||:||||||:..|||:|||||||||.||..|||
Zfish 1060 LLHLTMHDYPPLVSRALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVENYKQIKSDLDQLRSIVEK 1124
Fly 1233 SELWVYKAKATDELGATDAGGDAVSLEYNAALSQEQRNE----------YRKVKEILIRMNKFCV 1287
|||||||.:.:| ...|||.......:...::..:.|: ||.|||||:|::|.||
Zfish 1125 SELWVYKRQGSD--SGLDAGEVTPEAHHKGVINSSRSNKPKVESTSSSNYRVVKEILLRLSKLCV 1187
Fly 1288 TASGPGSVVKPRKHEQRLLRNVGVHTVVLDLLQNPYDEKDDELMKELMCLAHEFLQNFCLGNQQN 1352
.....|. |.:|.:||||||:|.|:|||:|||.||::.:|..|:|:|.|||:||||||.|||||
Zfish 1188 LEGISGK--KNKKQQQRLLRNMGAHSVVLELLQIPYEKGEDVQMQEIMTLAHQFLQNFCAGNQQN 1250
Fly 1353 QVLLHNHLDLFLNPGILEAKTVCAIFKDNLALCNEVTDKVVQHFVHCIEIHGRHVAYLQFLQTVV 1417
|.|||.|::||||||||||.|:..||.:|..||:|:.::||||||||||.|||.|.||:||||:|
Zfish 1251 QALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRSVHYLKFLQTIV 1315
Fly 1418 RAENQFIRRCQDMVMQELINSGEDVLVFYNDKGSFNHFVQMMQQQMLRMEKLSDDSPLKYHVELV 1482
:|||:||::|||:||.||:.:||||||||||:.||...||||: |..|:|.:.|.|:||:.||
Zfish 1316 KAENKFIKKCQDIVMAELVTAGEDVLVFYNDRASFQSLVQMMR---LERERLDESSALRYHIHLV 1377
Fly 1483 KLLACCTMGKNVYTEIKCNNLLSLDDIVTIICHPLCMPEVKEAYVDFLNHCYIDTEVEMKEIYAS 1547
:|||.||.|||||||||||:||.|||||.::.|..|:||||.|||:||||||:||||||||||.|
Zfish 1378 ELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKMAYVNFLNHCYVDTEVEMKEIYTS 1442
Fly 1548 GHMWSLFEKSFLVDINQLITNPA--AASNKTLQAYVLNGVTNLLGSFFASPFSDQSAIVQSRQLI 1610
.|||.||: .||||:.::..|.: ..::..|:.||...:.:::.:||:|||||||..:|:||.:
Zfish 1443 NHMWKLFD-DFLVDVCRVCNNTSDRKHADTVLERYVTETIMSIVTTFFSSPFSDQSTSLQTRQPV 1506
Fly 1611 FVQLLQAAHRITQCRWLSLGDRFNVENCIRTLTESAKMRSIALPPELEQQVATMSSKTAMLTRQT 1675
||||||...|:..|.||..|.:.|||.||:.|::.||.|:||:|.:|:.||..:..|:..:.::|
Zfish 1507 FVQLLQGVFRVYHCNWLLPGQKGNVEACIKVLSDVAKGRAIAIPVDLDCQVNNLFMKSNNIVQKT 1571
Fly 1676 T-KWLLASKQPKYEAQQAASLM---RWDRSIIEGLQDIVSLLEDQLKPVVEAELSLLVDILYRSE 1736
. .|.|:.: .|.:..|:: |..|:|||.||||||.||::|:|:|:||||:|||:|:|.|
Zfish 1572 ALSWRLSVR----NATRRDSVLTTSRDYRNIIERLQDIVSALEERLRPLVQAELSVLVDVLHRPE 1632
Fly 1737 LLFPAGTEARKRCESGGFIRKLIKHTEKLLEEKEERMCVKVLRTLREMMAIDVNYGEK------- 1794
||||..|||.::|||||||.||||||::||||.|||:|:|||:||||||..|..||||
Zfish 1633 LLFPEHTEAHRKCESGGFICKLIKHTKQLLEENEERLCIKVLQTLREMMTKDRGYGEKLLGYDDE 1697
Fly 1795 ---------------------GDALRQTLLLRYFQTKSTPRLPEDEVPLLAAPLMDPAKQNHLVT 1838
|:||||.|:.||:..:|..| .:.:.......:.|... :.
Zfish 1698 MDVTEVVDISLPPKQQEDRQRGEALRQLLVNRYYGFRSGGR--RESLTSFGNSTLTPVGP---IK 1757
Fly 1839 HGPGAKYLQRAGKTLHEMQNHLDREGASDLVVELVIKSVHSPNIFVEAVELGIALLEGGNPIIQK 1903
..||. |.||..:|.|:|.|||||||||||::|::.:. |..:|.|::.|.||||||||.|||.
Zfish 1758 SQPGG--LSRAEMSLMEVQCHLDREGASDLVIDLIMNTT-SDRVFHESILLAIALLEGGNTIIQH 1819
Fly 1904 GMFQKFLSDDLNQAFFKVFFEKMKDAQQEIKSTVTVNTTDIAAKAHEHKQDTNLELDKIARKHGL 1968
..|::...|..::.||:||:::||.||.|||:||||||:|:..| .:.|...:.|...|:.|
Zfish 1820 SFFKRLTEDKNSEKFFRVFYDRMKVAQVEIKATVTVNTSDLGNK---RRDDNTPDKDTPQRRRG- 1880
Fly 1969 KSNGVVITEELKRELHNAGLATARAYGNARNIHSGEESSAISVNSPLEDILAEKLEKHKDSRDQR 2033
|.:|||:|::.:.:|..|..||.:|:|:.|.....||:.. .|:..:...|...::
Zfish 1881 KDSGVVVTDDAREQLLEASAATKKAFGSYRRDADPEETFG----------TADGDKGGGDKGTEQ 1935
Fly 2034 NQLSNKVLVMQPILRFLQLLCENHNPDMQNLLRNQNNKTNNNLVSETLMFLDCICGSTTGGLGLL 2098
.::|..:|:||||||||||||||||.|:||.||.||||.|.|||.|||.||||||||||||||||
Zfish 1936 GEMSPVILIMQPILRFLQLLCENHNRDLQNFLRCQNNKNNYNLVCETLQFLDCICGSTTGGLGLL 2000
Fly 2099 GLYINEHNVALINQTLEALTEYCQGPCHENQNCIATHESNGLDIITALILNNINPLGENRMDLVL 2163
|||||:|||||||||:|:||||||||||:||||||||||||:|||.|||||:|||||..||||||
Zfish 2001 GLYINQHNVALINQTVESLTEYCQGPCHDNQNCIATHESNGIDIIIALILNDINPLGRKRMDLVL 2065
Fly 2164 ELKNNASKLLLAIMESRGDSENAERILYNMNPKQLVEVACKAYHQEEL---IDEQDDGDEPDAGS 2225
|||||||||||||||||.||||||||||||.||:||||...||.|.|. .:||::|
Zfish 2066 ELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVMKMAYQQGEAEFEDEEQENG------- 2123
Fly 2226 DDDDATVSPREVGHNIYILCHQLAQHNKELAGLLK-ASEDPQSASFDAKTSQALMYYATHTAQIE 2289
:|...|||.||||||||.|||::|||||..||| ..|| |||.||..||:|||
Zfish 2124 --EDHAASPRNVGHNIYILAHQLSRHNKELQILLKPGGED-----------QALEYYTKHTSQIE 2175
Fly 2290 IVRNDRTLEQIVFPIPEICEYLTTDTKIKILNTAERDDQGSKVADFFDKAEEMFNEMKWQKKLRS 2354
|||.|||:||||||:|.||.:||.::|:::....|||:||||:.|||..|:::||||:||||||:
Zfish 2176 IVRQDRTMEQIVFPVPNICSFLTNESKLRVYYGTERDEQGSKINDFFLHADDLFNEMRWQKKLRA 2240
Fly 2355 QPLLFWISSYMSLWSNILFNCVVVINMIVAFFYPFDN-TVPELSSHISLLFWIITIFSLVIVLAL 2418
||:|:|.|..||.|||:.||..|:||::||||||.|. :..:|...:|||.|:..:.||..||..
Zfish 2241 QPVLYWCSRNMSFWSNVSFNLAVLINLLVAFFYPLDGVSESQLEPSLSLLLWVCLLGSLGFVLMS 2305
Fly 2419 PRESGIRTFIGSVILRFIFLLGPESTLCLLGVVTVTLKSVHIVSIMGNKGTLEKQLIKIITDFQL 2483
||.:.:|..:.|.:|:..|.:|.:..|.|||...|..|.|.::|.:||:|:..:....::.|.:.
Zfish 2306 PRPNAVRVLVISTVLQLGFSVGLQHMLTLLGAFNVCNKIVFMLSFVGNRGSFTRGYRVMVMDREF 2370
Fly 2484 LYHCIYIAFCFCGLIFHPFFYSLLLFDVVYREETLVNVIRSVTRNGRSIVLTAVLALILVYLFSI 2548
|:|.:|:..|..||..|.|||||||||:|.|||||:|||:|||||||||||||||.|||||||||
Zfish 2371 LFHLLYLLICILGLFGHVFFYSLLLFDLVNREETLLNVIKSVTRNGRSIVLTAVLGLILVYLFSI 2435
Fly 2549 IGYMFFKDDFLVSVD------FEEQDNAPPPSVPLTLSVPVSGDSCSAPDDLGNCQAAKEVAPPS 2607
:|||||||||::.|: .|| .|.:....|.|.: |:| .:.:|....
Zfish 2436 VGYMFFKDDFILEVNRISNGTLEE-------------GVTLPAGFCDARN--GSC-LSDDVDEDD 2484
Fly 2608 AGGGEVKERSCDSLVMCIVTTLNQGLRNGGGIGDILRAPSSKEGLFVARVIYDLLFFFIVIIIVL 2672
. ||:||||.||::|.|:.|||:|||:||:||.||.:|.||.|||:|||||||:||||||
Zfish 2485 V------ERACDSLWMCMITVLSHGLRSGGGVGDVLRKPSKEERLFAARVVYDLLFFFLVIIIVL 2543
Fly 2673 NLIFGVIIDTFADLRSEKQQKEAILKTTCFICSLNRSAFDNKTVSFEEHIKSEHNMWHYLYFIVL 2737
|||||||||||||||||||:||.|||||||||.|.|..||||||:||||||.|||:||||:||||
Zfish 2544 NLIFGVIIDTFADLRSEKQRKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNLWHYLFFIVL 2608
Fly 2738 VKVKDPTEFTGPESYVYAMVKAGILEWFPRLRAMSLAAVDADGEQIELRSMQAQLLDTQLLIKNL 2802
|:|||.||:|||||||..|:|...|:||||:|||||.:.|.:|||.||||:|.:|..|..|:.||
Zfish 2609 VRVKDSTEYTGPESYVAQMIKEHNLDWFPRMRAMSLVSSDGEGEQNELRSLQEKLESTMRLVSNL 2673
Fly 2803 STQLHELKDHMTEQRKQKQRLGLLNTTAN 2831
:.||.|||:.||||||.|||||||...|:
Zfish 2674 TNQLTELKEQMTEQRKHKQRLGLLGNPAH 2702
| 
