|
Fly 9 ASFLHLGDIVSLYAEGSVCGFLSTLGLVDDRTVVCPEAGDLSCPPKKFRDCLIKICPMNRYSAQK 73
:||||:||||||||||:||||:|||||||||.||.|.||||..|||||||||.::||||||||||
Frog 5 SSFLHIGDIVSLYAEGTVCGFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFRVCPMNRYSAQK 69
Fly 74 QFWKA--AKQSASSNTDPNLLKRLHHAAEIEKKQNETENKKLLGTSIQYGRAVVQLLHLKSNKYL 136
|:||| |||.....:|..||::|.|||.:|:|||||||||:.|..::|| :|:||||:||||||
Frog 70 QYWKAKQAKQDKEKISDVLLLQKLQHAANLEQKQNETENKKVHGEVVKYG-SVIQLLHMKSNKYL 133
Fly 137 TVNKRLPSLLEKNAMRVYLDANGNEGSWFYIKPFYKLRSIGDYVVVGDKVILSPVNADQQNLHVA 201
|||||||:|||||||||.||..|||||||:|:||:||||.||.|||||||.|:||||.|. || |
Frog 134 TVNKRLPALLEKNAMRVTLDVTGNEGSWFFIQPFWKLRSNGDNVVVGDKVNLNPVNAGQP-LH-A 196
Fly 202 ANYELPDNPGCKEVNVLNSSTSWKISLFMEHKENQEHILKGGDVVRLFHAEQEKFLTMDEYKKQY 266
:||||.|||||||||.|||:|||||:|||::::..|.:|||||||||||||||||||.||||.:.
Frog 197 SNYELTDNPGCKEVNSLNSNTSWKINLFMQYRDYMEDVLKGGDVVRLFHAEQEKFLTCDEYKSRL 261
Fly 267 HVFLRTTGRTSATAATSSKALWEIEVVQHDSCRGGAGDWNSLYRFKHLATGHYLAAEAEIDVSAG 331
|||||||.|.|||:||||.||||:|||.||.||||||.|||||||||||||||||||.
Frog 262 HVFLRTTLRQSATSATSSNALWEVEVVHHDPCRGGAGHWNSLYRFKHLATGHYLAAEE------- 319
Fly 332 AMSATSASGHDLHLGDCSK-DSGLSCSTMNSTINDKPKGK------QYRLVSVPYSADIASVFVL 389
:..:.||..: .||.| |:.::.:|..| ::|||:||:..||||:|.|
Frog 320 ---------NPAYKGDAPEFKSGSS----NAVVSTRPSRKNAGEKIKFRLVAVPHGNDIASLFEL 371
Fly 390 DATTMARPDSLVPQSSYVRLQHICSNTWVHATSIPIDADDDKPVMSMVCCSPIKEDKEAFALIPV 454
|.||:.:.|||||::|:|||:|:|:|||:.:|::|||.|:::|:..|:...|.||||||||::.|
Frog 372 DPTTLQKTDSLVPRNSFVRLRHLCTNTWIQSTNVPIDVDEERPIRLMLGTCPTKEDKEAFAIVSV 436
Fly 455 SPVEVRDLDFANDACKVLATVTSKLDNGSISINERRALISLLQDIVYFIAGMENEQNKTKALEFT 519
...|:|||||||||..:||....:|:.|.||.|:||..|.||:|:|:|:..:.| |....|:..
Frog 437 PVSEIRDLDFANDASSMLANFVERLNEGFISQNDRRFAIKLLEDLVFFVVDVSN--NGQNVLDIM 499
Fly 520 IKNPIRDRQKLLREQYILKQLFKILQGPFQQHTAGDGPFLRLDELSDPKNSPYKNIFRLCYRILR 584
|..|.|:||||:|||.||||:|.||:.||:: ...|||.|||:||||.|||||:.:||||||:||
Frog 500 ITKPNRERQKLMREQNILKQIFGILKAPFKE-KGTDGPLLRLEELSDQKNSPYQYMFRLCYRVLR 563
Fly 585 LSQQDYRKNQEYIAKHFGLMQKQIGYDILAEDTITALLHNNRKLLEKHITAAEIETFVGLVRKNM 649
.||:|||||||:|||.||:||.||||||||||||||||||||||||||||..|:||||.|||||.
Frog 564 HSQEDYRKNQEHIAKQFGVMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVNLVRKNR 628
Fly 650 HNWDSRFLDYLSDLCVSNRKAIAVTQELICKSVLSDKNKDILIETQVKALRTGSGPVRCYKGNSE 714
:.|||||||||||||..||.||||||||.||..||.||||:|:::.|:..|......:...|
Frog 629 ---EPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIKTELRPLKEMSPEYMSLEYCDE 690
Fly 715 DVCLATLAEDAGDDEDRSDVQSTSTTTTWDSASLNEDDGTPSTGDKYEIHLKWTGQPTSRSMADL 779
:|.| || |....|.:|..::...|....
Frog 691 EVWL-----------------------TW----------TDKNNDSHEKSIRQLSQEARA----- 717
Fly 780 ASCDGGELEAAILNYYRHQLNLFSNMCLNRQYLALNELSPRLDIDLILKCMSDETMPYELRASFC 844
|...:..:|.|||:||.||:.|||:|||||::|:|.:|.:|||..||:||.:|||:|||||
Frog 718 ----GNAHDENVLTYYRYQLKLFARMCLDRQYLAIHEISKQLSVDLIFLCMADEMLPYEIRASFC 778
Fly 845 RLMLHLHVDRDPQEPVTPVKYARLWSEIPSKMSIQDYDGKNQQPDQNKQACRAKFNTTIAFVENY 909
.||||:||||||||.|||||:||||:|||..::|:|||........|| :.||.:|:.|||:|
Frog 779 HLMLHVHVDRDPQELVTPVKFARLWTEIPMAITIKDYDSNLNDSRDNK---KNKFTSTMEFVEDY 840
Fly 910 LCNVATKVWLFTDQEQNKLTFEVVKLARDLIYFGFYSFSDLLRLTKTLLSILDCVSDTSSGEFAS 974
|.||.::...|:.:::||||||||.|||.||||||||||:|||||:|||.|:|||.:.. |
Frog 841 LNNVVSESMPFSHEDKNKLTFEVVSLARHLIYFGFYSFSELLRLTRTLLGIIDCVQNPQ-----S 900
Fly 975 TDIDSVEEETNAEAEG-GVLRSIGDINTVMTSLALG------SVGQAIAA------PTISLQQRK 1026
..:.::..| :..| .|.|||..:..:::::.|. |..|:::: |. :||
Frog 901 ILLQAIYSE---DGTGKNVRRSIHGVGQMVSTMVLNRKQTGYSSSQSLSSVVNHETPI----KRK 958
Fly 1027 SVSQLMKEYPLVMDTKLKIIEILQFILDVRLDYRISCLLSIFKREFDESEVAASAASNEASQQQS 1091
:|.. |..:||:|||||:|||||||:||||||||.|||:||:||
Frog 959 NVDM---ENIIVMETKLKILEILQFILNVRLDYRISYLLSVFKKEF------------------- 1001
Fly 1092 QQQEPQTPGSSNETDPLDSAESVAAGAAAAAATTARQKNIDLESIGVQAEGIFDCERSDAANLDL 1156
.|..|:. ::.|.|.|.|..:| ..:::|:.||..||.:|...:| .:.|::
Frog 1002 -----------VEVFPMQ--DNAADGTAPAFDST--NASLNLDRIGELAEAMFGVGKS-TSMLEV 1050
Fly 1157 DGQGGRTFLRVLLHLIMHDYAPLVSGALHLLFRHFSQRQEVLQAFRQVQLLVSDSDVESYKQIKS 1221
|.:|||.|||||:.|.|:||..|:||:|.|||:|||||||||..|:|||||:|..||::||.|||
Frog 1051 DDEGGRMFLRVLIQLTMNDYPSLISGSLQLLFKHFSQRQEVLHTFKQVQLLISTQDVDNYKVIKS 1115
Fly 1222 DLDILRQSVEKSELWVYKAKATDELGATDAG----GDAVSLEYNAA--LSQEQRNEYRKVKEILI 1280
:||.||..||||||||.|...|..:|:||.. .:.|..:.|:. :.::....|:.||.||.
Frog 1116 ELDRLRTMVEKSELWVDKKGNTGIIGSTDGNKKDKKEHVENQDNSGKPVMEKSSENYQIVKGILE 1180
Fly 1281 RMNKFCVTASGPGSVVKPRKHEQRLLRNVGVHTVVLDLLQNPYDEKDDELMKELMCLAHEFLQNF 1345
.:||.| :||..| ||.:||||:|:..|.|:|||||.|| ||:|..|||::...|:|||.|
Frog 1181 TLNKMC---NGPEQV---RKKQQRLLKNMDAHKVMLDLLQVPY-EKEDTKMKEILKYTHQFLQKF 1238
Fly 1346 CLGNQQNQVLLHNHLDLFLNPGILEAKTVCAIFKDNLALCNEVTDKVVQHFVHCIEIHGRHVAYL 1410
|..|.:||.|||.||.|||.||:.||:|:..||.:|..||:|:.:.|:|||:||:..|||||.||
Frog 1239 CATNPENQALLHKHLSLFLTPGLQEAETMQHIFLNNYQLCSEIHEAVLQHFIHCLATHGRHVQYL 1303
Fly 1411 QFLQTVVRAENQFIRRCQDMVMQELINSGEDVLVFYNDKGSFNHFVQMMQQQMLRMEKLSDDSPL 1475
.||.|:::||.::|::||||:|.||.|:|:||:||||||.||...::|| ....|.:.::|||
Frog 1304 DFLHTIIKAEGKYIKKCQDMIMTELTNAGDDVVVFYNDKASFASMLEMM---ATAREAIEENSPL 1365
Fly 1476 KYHVELVKLLACCTMGKNVYTEIKCNNLLSLDDIVTIICHPLCMPEVKEAYVDFLNHCYIDTEVE 1540
|||:.||.|||.|..||||||||||.:||.|:|:|.::.|..|:.|||.:||:|:||||:|||||
Frog 1366 KYHISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVRVVTHEDCITEVKISYVNFVNHCYVDTEVE 1430
Fly 1541 MKEIYASGHMWSLFEKSFLVDINQLITNPAAASNK--------TLQAYVLNGVTNLLGSFFASPF 1597
|||||.|.|:|:||| :|::|: |...|| ||:.|||..|...:.|||.|||
Frog 1431 MKEIYTSNHIWTLFE-NFILDM-------ARVCNKREKRIVDSTLEKYVLTVVLETIRSFFNSPF 1487
Fly 1598 SDQSAIVQSRQLIFVQLLQAAHRITQCRWLSLGDRFNVENCIRTLTESAKMRSIALPPELEQQVA 1662
|:.|..:|:.|.|.|||||:..|:.:|.||....:.:||.|||.|...||.|||:||.:|:..|:
Frog 1488 SENSTSLQTHQTIVVQLLQSTTRLLECPWLLQQYKVSVEACIRALAMLAKSRSISLPMDLDTHVS 1552
Fly 1663 TM--SSKTAMLTRQTTKWLLASKQPKYEAQQAASLMRWD-RSIIEGLQDIVSLLEDQLKPVVEAE 1724
:: ||.:|:...|:| ..:...:..|:.:|:..:|| ::|:|.||||:::||::|||:||||
Frog 1553 SLLNSSSSALQRNQST---YKTTSTRSFARGSATQNQWDYKNIVEKLQDIINILEERLKPLVEAE 1614
Fly 1725 LSLLVDILYRSELLFPAGTEARKRCESGGFIRKLIKHTEKLLEEKEERMCVKVLRTLREMMAIDV 1789
||:|||:|...||||..||:||.||||||||.|||:||:.|: ..||::|:||||||::|:....
Frog 1615 LSVLVDVLQHPELLFAEGTDARLRCESGGFISKLIQHTKNLM-SSEEKLCIKVLRTLQQMLMKKR 1678
Fly 1790 NYGEKGDALRQTLLLRYFQTKSTPRLPEDEVPLLAAPLMDPAKQNHLVTHGPGAKYLQRAGKTLH 1854
||||:|:.||:|||..|...|......|.......|...|.| .:.
Frog 1679 NYGEQGNMLRRTLLNIYLHNKKLNPKGETSDSFAIAQDQDWA--------------------MIA 1723
Fly 1855 EMQNHLDREGASDLVVELVIKSVHSPNIFVEAVELGIALLEGGNPIIQKGMFQKFLSDDLNQAFF 1919
.:|..||||||:.||.:|::.| .:..||.|::.|.|.||:|||..||...:.....|:.::.||
Frog 1724 SIQCKLDREGATKLVSDLIMSS-KNEKIFQESILLAIRLLDGGNTEIQNSFYNLMKGDNKSEKFF 1787
Fly 1920 KVFFEKMKDAQQEIKSTVTVNTTDIAAKAHEHKQDTNLELDKIARKHGLKSNGVVITEELKRELH 1984
||..|:||.||||||||::||..|:. ||| ..|.|.|.....| :|..||
Frog 1788 KVLNERMKCAQQEIKSTMSVNMNDLG--AHE-PDDENAEYPPKGR-----NNQYVI--------- 1835
Fly 1985 NAGLATARAYGNARNIHSGEESSAISVNSPLEDILAEKLEKHKDSRDQRNQLSNKVLVMQPILRF 2049
:|..:.|...|:.|..|...::. :.|::...||:|:|||||
Frog 1836 HASTSRAITGGSFRKGHDVADNG------------------------ESNEVGPAVLIMEPILRF 1876
Fly 2050 LQLLCENHNPDMQNLLRNQNNKTNNNLVSETLMFLDCICGSTTGGLGLLGLYINEHNVALINQTL 2114
|||||||||.|:||.||||.||||.|||.|||.|||.:|||||||||||||||||.|||||.|||
Frog 1877 LQLLCENHNSDLQNFLRNQTNKTNYNLVCETLQFLDIMCGSTTGGLGLLGLYINEKNVALIIQTL 1941
Fly 2115 EALTEYCQGPCHENQNCIATHESNGLDIITALILNNINPLGENRMDLVLELKNNASKLLLAIMES 2179
|.|||||||||||||:||.||||||:||||||:||:|:||.:.||||||:||:||||||||:|||
Frog 1942 ETLTEYCQGPCHENQSCIVTHESNGIDIITALVLNDISPLCKYRMDLVLQLKDNASKLLLALMES 2006
Fly 2180 RGDSENAERILYNMNPKQLVEVACKAYHQEELIDEQDDGDEPDAGSDDDDATVSPREVGHNIYIL 2244
|.|||||||||.::.|::||.|..|||.||| :||..| |||:|||||||||
Frog 2007 RHDSENAERILISLRPQELVSVIKKAYMQEE------EGDSSD---------VSPQEVGHNIYIL 2056
Fly 2245 CHQLAQHNKELAGLLK----ASEDPQS--------------------ASFDAKTSQALMYYATHT 2285
..||::|||.|..||| ..|:.:| |....:....|.|||.||
Frog 2057 ALQLSRHNKHLQHLLKPVKRIQEEEESISTMLSLNNKQLTQMLKSTTAPVQEEEEDPLAYYAKHT 2121
Fly 2286 AQIEIVRNDRTLEQIVFPIPEICEYLTTDTKIKILNTAERDDQGSKVADFFDKAEEMFNEMKWQK 2350
|||||||.||::|||||.:|.||::||.:||.::..|.|:|||||||:||||::..:.|||:||:
Frog 2122 AQIEIVRMDRSMEQIVFSVPSICKFLTEETKHRVFTTTEQDDQGSKVSDFFDQSSFLHNEMEWQR 2186
Fly 2351 KLRSQPLLFWISSYMSLWSNILFNCVVVINMIVAFFYPF--DNTVPELSSH-ISLLFWIITIFSL 2412
||||.||::|.|..|:||..|.||..|.||:|:|||||: ..::..|.|. ||||||.:..||:
Frog 2187 KLRSMPLIYWFSRRMTLWGTISFNLAVFINLIIAFFYPYVEGTSIGILDSPLISLLFWGMVCFSV 2251
Fly 2413 VIVLALPRESGIRTFIGSVILRFIFLLGPESTLCLLGVVTVTLKSVHIVSIMGNKGTLEKQLIKI 2477
:.:.. :..|.|..|.::|||.::.||...||.:||.:.:|.|.|.:||.:||:||..:....:
Frog 2252 MSLFT--KRYGFRPLIVALILRSVYYLGIGPTLYILGALNLTNKIVFVVSFVGNRGTFIRGYKAM 2314
Fly 2478 ITDFQLLYHCIYIAFCFCGLIFHPFFYSLLLFDVVYREETLVNVIRSVTRNGRSIVLTAVLALIL 2542
:.|.:.|||..||.....||..|..|||:||||::||||||.|||:|||||||||:|||:|||||
Frog 2315 VMDVEFLYHVAYILTSVLGLFIHELFYSILLFDLIYREETLFNVIKSVTRNGRSILLTALLALIL 2379
Fly 2543 VYLFSIIGYMFFKDDFLVSVDFEEQDNAPPPSVPLTLSVPVSGDSCSAPDDLGN-CQAAKEVAPP 2606
||||||:|::|.||||::.| |..|..:.|: ||::... |: |:....
Frog 2380 VYLFSIVGFLFLKDDFIMEV-----DRLPKATSPM------------APNNFAEFCE--KDQTDC 2425
Fly 2607 SAG----------GGEVKERSCDSLVMCIVTTLNQGLRNGGGIGDILRAPSSKEGLFVARVIYDL 2661
:.| .|:| ||:||:|:|||:|.||.|||||||:|||||.||..|.||.||::|||
Frog 2426 TVGVTTLDEIEDEEGDV-ERACDTLLMCIITVLNHGLRNGGGVGDILRKPSKDETLFPARIVYDL 2489
Fly 2662 LFFFIVIIIVLNLIFGVIIDTFADLRSEKQQKEAILKTTCFICSLNRSAFDNKTVSFEEHIKSEH 2726
||||||||||||||||||||||||||||||:||.:||||||||.|.|..|||||||||||||.||
Frog 2490 LFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEVLKTTCFICGLERDKFDNKTVSFEEHIKEEH 2554
Fly 2727 NMWHYLYFIVLVKVKDPTEFTGPESYVYAMVKAGILEWFPRLRAMSLAAVDADGEQIELRSMQAQ 2791
|:|:||||||||:||:.|::|||||||..|:|...|:||||:|||||.:.:.:|||.|:|.:|.:
Frog 2555 NIWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNKNLDWFPRMRAMSLVSNEGEGEQNEIRILQDK 2619
Fly 2792 LLDTQLLIKNLSTQLHELKDHMTEQRKQKQRLGLL-------NTTANS 2832
|..|..|:.:|:.||.|||:.||||||::||:|.: |||.||
Frog 2620 LGSTMRLVSHLTMQLSELKEQMTEQRKRRQRMGFVDVQNNVGNTTTNS 2667
| 
