Protein Alignment NKCC and CCC1

DIOPT Version :9

• Sequence 1: NP_730938.1
• Gene: NKCC / 40663
• FlyBaseID: FBgn0051547
• Length: 1068
• Species: Drosophila melanogaster
• Sequence 2: NP_174333.2
• Gene: CCC1 / 839924
• AraportID: AT1G30450
• Length: 975
• Species: Arabidopsis thaliana
• Alignment Length: 1091
• Identity: 259/1091 - (23%)
• Similarity: 464/1091 - (42%)
• Gaps: 261/1091 - (23%)

  Fly    52 ETGEN--RRSSRLSFRGFGNF-----LRKSDAERKFSLAQLTKESLPRLDNYRISMRNLKRPSIG 109
            |.|.|  ::.|:|...||.:.     |:....|      |:...|.||
plant    72 EDGVNGHQKESKLELFGFDSLVNILGLKSMTGE------QIQAPSSPR----------------- 113

  Fly   110 ELQGEAVDQSITIPEPEPEATGGHIKLGWIVGVLIPCLLNIWGVMLFLRLSWVVAESGILQSLII 174
              .||  |.|||...|:|.|    :|:|.::||.:|||.||.|::.::|.:|:|..:||.|.|::
plant   114 --DGE--DISITQGHPKPPA----LKMGTMMGVFVPCLQNILGIIYYIRFTWIVGMAGIGQGLVL 170

  Fly   175 ITISAVVCVITTLSLSAISTNGEVKGGGVYFIISRSLGPEFGASVGVVFAFANAVSASMNTIGFC 239
            :.:..:...:||:|||||:|||.:||||.|::|.|:||||.|.|:|:.|...|||:.::..:|..
plant   171 VFLCGLCTFLTTISLSAIATNGAMKGGGPYYLIGRALGPEVGISIGLCFFLGNAVAGALYVLGAV 235

  Fly   240 ESL-----------NVLLKNNDLKIVDN----GINDIRIVGSITVLVLILICCVGMEWETKAQNF 289
            |:.           ..:.|.|...:.::    ..:|:::.|.:..::|..|...|::...:....
plant   236 ETFLKAFPAAGIFRETITKVNGTAVSESIQSPNSHDLQVYGIVVTILLCFIVFGGVKMINRVAPA 300

  Fly   290 LIVTIVLAIFNFLIGAAIGPQGNEEQISRGFVGFSWATLKENFGSDYRYAE---------GVNHD 345
            .:|.::|:||...||..:....:.:   .|..|....:.|:|:||.|:...         |....
plant   301 FLVPVLLSIFCIFIGIFLAKTDDPD---NGITGLRLKSFKDNWGSAYQMTNDAGIPDPTGGTYWS 362

  Fly   346 FFSVFAIFFPSVTGIQAGANICGDLKDAGAAIPKGTFWSLLISMSSYALFVLFAGGAAVRDASGI 410
            |..:..:|||:||||.||:|....|||...:||.||..:.|.:.|.|.:.|||.|..|.||
plant   363 FNELVGLFFPAVTGIMAGSNRSASLKDTQKSIPVGTLAATLTTTSLYLISVLFFGAVATRD---- 423

  Fly   411 PADLVNGTIVSSELPCMATGNCTWGLFNSYEMMQEMSLWGPLIYAGCFAATLSTALTNLLSVPRL 475
                   .:::..|   .|....|.             :..:::.|...:||..||.:|...|||
plant   424 -------KLLTDRL---LTATIAWP-------------FPAIVHVGIILSTLGAALQSLTGAPRL 465

  Fly   476 VQALGIDQIYPGLIFFSKPYGKHGEPYRGYVLTFFITTGFLLIGELNLIAPLISTFYLASYALIN 540
            :.|:..|.|.|.|.:|.  .....||:...:.|.||..|.::||.|:||.|.::.|||..|:.:|
plant   466 LAAIANDDILPILNYFK--VADTSEPHIATLFTAFICIGCVVIGNLDLITPTVTMFYLLCYSGVN 528

  Fly   541 FCTFHAAFVKPLGWRPTFKYYNAWLSLFGFAMCVAIMFLINYVAAIITFGIIFALYLVVMYRKPE 605
            ...|....:....|||.:||::..||..|.::|:.|||||::...::...:...:|..|..:...
plant   529 LSCFLLDLLDAPSWRPRWKYHHWSLSFVGASLCIVIMFLISWSFTVVAIALASLIYKYVGLKGKA 593

  Fly   606 ANWGSTTQAQQYKAALMAVHRLQNVSDHVKNYHPQVLV-------LSGDPKTRPPLVDFGYLLTK 663
            .:||...::..::.||.::..|.....|.||::|..||       |..:....|.|.||...:.|
plant   594 GDWGDGFKSAYFQLALRSLRSLGANQVHPKNWYPIPLVFCRPWGQLPENVPCHPKLADFANCMKK 658

  Fly   664 NNSLMFVANIIPVRVG-YKNRQHLVKDGQK----YLDARKIKAFYNVIDGFSLEDGINALTKSTG 723
            ....|.:  .:.:..| |.......|:..|    |::.::.:....::...::.:|...:.::.|
plant   659 KGRGMSI--FVSILDGDYYECAEEAKEACKQLATYIEYKRCEGVAEIVVAPNMTEGFRGIIQTMG 721

  Fly   724 FGKMSPNIVLVGYKPDWNRCRKEEVESYF-SILYNAFSQRMGVALLRLPNGLDFSELSSEVTLPA 787
            .|.:.||||::.|...|.|....|:.|.| .|:.:..:....|.:::   |||
plant   722 LGNLKPNIVVMRYPEIWRRENLTEIPSTFVGIINDCITANKAVVIIK---GLD------------ 771

  Fly   788 NGMGHMHTANAHGFTNELMPAANAASELLHIDSNLNLASMDSPNSSFTMPQPAPMPNMQRNSRSY 852
                                                    :.||               ...|.|
plant   772 ----------------------------------------EWPN---------------EYQRQY 781

  Fly   853 KVTSSDEPAVTYHTKGGSDIPQNLLDAMTIFTRKQPKGTIDVFWLYDDGGLTILLPYIISMRSHW 917
                                                 ||||::|:..||||.:||..::..:..:
plant   782 -------------------------------------GTIDLYWIVRDGGLMLLLSQLLLTKESF 809

  Fly   918 QNSKLRVFAMCHGKDEEQEEKSMASLLTKFRI---KYSELIML---------KGVSEQPRADTVL 970
            ::.|:::|.:.   :|:.:.:::.:.:.||..   .::|:|::         :|.|::...:...
plant   810 ESCKIQLFCIA---EEDSDAEALKADVKKFLYDLRMHAEVIVVTMKSWDIRSEGNSQEDSLEAFD 871

  Fly   971 KHKRLIEPF-----RRGAR-----------NEFGITDDELQSMSEKTNRQLRIHELVVKHSSNAS 1019
            ..:|.|..:     |:|:.           ||        |.:.:.....|:::..::.:|..|:
plant   872 AAQRRISDYLGEIKRQGSNPLLANGKPMVVNE--------QQVEKFLYTMLKLNSTILSYSRMAA 928

  Fly  1020 LVVMSLPMPRKEAISAP--LYMSWLEMLTSDMKCPVALARGNQTPVLTLYS 1068
            :|::|||.|   .::.|  .||.::::|..::. .:.:.||....|:||::
plant   929 VVLVSLPPP---PLNHPAYFYMEYMDLLVENVP-RMLIVRGYHRDVVTLFT 975

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NKCC	NP_730938.1	2a30	85..1068	CDD:273347	249/1049 (24%)
		DUF502	507..>643	CDD:294696	41/135 (30%)
		SLC12	651..1068	CDD:281515	77/452 (17%)
CCC1	NP_174333.2	2a30	56..975	CDD:273347	259/1089 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	278	1.000	Domainoid score	I408
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57166
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11827
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020