Protein Alignment NKCC and zgc:153039

DIOPT Version :9

• Sequence 1: NP_730938.1
• Gene: NKCC / 40663
• FlyBaseID: FBgn0051547
• Length: 1068
• Species: Drosophila melanogaster
• Sequence 2: XP_021337145.1
• Gene: zgc:153039 / 767698
• ZFINID: ZDB-GENE-060929-736
• Length: 942
• Species: Danio rerio
• Alignment Length: 1075
• Identity: 273/1075 - (25%)
• Similarity: 458/1075 - (42%)
• Gaps: 235/1075 - (21%)

  Fly    88 ESLPRLDNYRISMRNLKRPSIGELQGEAVD--QSITIPEPEPE-----------ATGGHIKLGWI 139
            |..|.| :||:|       :.|...||..:  |:.:....||:           |.....||...
Zfish     3 ERTPLL-HYRLS-------ASGHEPGEPREHRQTTSAGHEEPDTRSRRPGARNPAAAQPPKLNTF 59

  Fly   140 VGVLIPCLLNIWGVMLFLRLSWVVAESGILQSLIIITISAVVCVITTLSLSAISTNGEVKGGGVY 204
            .||:||.||:::.|::|||:.:||.:.|:.|::.::.::..:..:|.||:.||||||.:..||.|
Zfish    60 FGVVIPTLLSMFSVVVFLRIGFVVGQCGLYQTIAMLLVAYFIISMTVLSVCAISTNGALDAGGAY 124

  Fly   205 FIISRSLGPEFGASVGVVFAFANAVSASMNTIGFCESLNV---LLKNNDLKIVDNGINDI----- 261
            ::|||:||||||.|:|::|..||...:::..:|..|::..   |..:..|.:..:.:..:
Zfish   125 YMISRALGPEFGGSIGIMFFLANVCGSALYVLGLVEAVLTTFGLPDDGSLSMSRSAVLPVGYWWS 189

  Fly   262 RIVGSITVLVLILICCVGMEWETKAQNFLIVTIVLAIFNFLI----------------GAAIGPQ 310
            .:.|::.:|:.:|:|.||.....|| .|||..||:.:...:.                .:.|||
Zfish   190 LLYGTVILLLCVLVCLVGAHIYAKA-TFLIFIIVMVVLGTIFISFFAVPFRTVQLPGSNSTIGP- 252

  Fly   311 GNEEQISR-GFVGFSWATLKENFGSDYR--YAEGVNHDFFSVFAIFFPSVTGIQAGANICGDLKD 372
                  || .|.||...||..|..:||.  |.......|.:|||:.|...|||.||:|:.||||:
Zfish   253 ------SRANFTGFKLDTLTGNLQADYTLDYTTKAMMSFATVFAVMFNGCTGIMAGSNMSGDLKN 311

  Fly   373 AGAAIPKGTFWSLLISMSSYALFVLFAGGAAVRDASGIPADLVNGTIVSSELPCMATGNCTWG-- 435
            ...:||:||..:::.:...|.|..|..                               :||..
Zfish   312 PSYSIPRGTITAVIFTFIIYNLLSLLI-------------------------------SCTCDRI 345

  Fly   436 -LFNSYEMMQEMSLWGPLIYAGCFAATLSTALTNLLSVPRLVQALGIDQIYPGLIFFSKPYGKHG 499
             |...|..::::::|||.:..|.:::|||.|::||:...|::.||..|.::..::..:|.....|
Zfish   346 LLQKDYGFLRDINVWGPFVTVGVYSSTLSAAMSNLIGASRILFALAKDDLFGRVLSPAKRTSASG 410

  Fly   500 EPYRGYVLTFFITTGFLLIGELNLIAPLISTFYLASYALINFCTFHAAFVKPLGWRPTFKYYNAW 564
            .|:...::::|:....|..|:||.||.:::.|:|..||.::.......:.....:||||:|:...
Zfish   411 NPWVSVLISWFLVQLVLFSGKLNTIASIVTIFFLLVYAAVDLACLALEWASAPNFRPTFRYFTWH 475

  Fly   565 LSLFGFAMCVAIMFLINYVAAIITFGIIFALYLVVMYRKPEANWGSTTQA----QQYKAALMAVH 625
            ..:.|...|..:|||||.:.|..:...:..|.|::.|..|.::||..:||    |..|..||
Zfish   476 TCVLGIIGCAVMMFLINAIYASASIAFMLLLLLLIHYLSPVSSWGCISQALIFHQVRKYLLM--- 537

  Fly   626 RLQNVSDHVKNYHPQVLVLSGDPKTRPPLVDFGYLLTKNNSLMFVANII-----------PVRVG 679
             |....||||.:.||||::..:|::...|:.|...:.|:.  ::|...:           |::..
Zfish   538 -LDVRKDHVKFWRPQVLLMVSNPRSSVGLITFINHIKKSG--LYVLGHVQLGDLDVLPSDPLQAQ 599

  Fly   680 YKNRQHLVKDGQKYLDARKIKAFYNVIDGFSLEDGINALTKSTGFGKMSPNIVLVGYKPDW---- 740
            |.:...||       |...||||.|:....|:..|:..|...:|.|.|.||.:::|:..|.
Zfish   600 YDSWLSLV-------DHLNIKAFVNLTLADSIRHGVQHLLFISGLGGMRPNTLVLGFYDDASPQD 657

  Fly   741 --------------NRCRKEEVESYFSILYNAFSQRMGVALLRLPNGLDFSELSSEVTLPANGMG 791
                          |..:.|:.|......::....|.|||:                     |.|
Zfish   658 QLQDSSLSMSKFLDNSSQNEDPEDQDEPPFHFPPVRGGVAV---------------------GRG 701

  Fly   792 HMHTANAHGFTNELMPAANAASELLHIDSNLNLASMDSPNSSFTMPQPAPMPNMQRNSRSYKVTS 856
            .:....:.|....:...|:|...|    .|:.||                     |....:..|
Zfish   702 AVWGGKSLGPQEYVCIIADAVKML----KNVALA---------------------RYFGQFDHT- 740

  Fly   857 SDEPAVTYHTKGGS---DI-PQNLLDAMTIFTRKQPKGTIDVFWLYDDGGLTILLPYIISMRSHW 917
                    |...|.   |: |.|||       |......:|...|:     .:.|..|::|...|
Zfish   741 --------HALQGPIFVDVWPVNLL-------RPDSAAYVDTCSLF-----LLQLACILNMTRAW 785

  Fly   918 QNSKLRVFAMC--HGKDEEQEEKSMASLLTKFRIKYSELIMLKGVSE-------QPRADTVLKHK 973
            |.::||:| :|  .|:..:..|:.:..||...|:| :::..:...||       |.|.|...|.:
Zfish   786 QKARLRLF-LCVEEGRSLKGTEQKLGHLLKDLRMK-ADICTVPWDSEVALHWQRQTRLDRNEKEE 848

  Fly   974 RLIEPFRRGARNEFGITDDELQSMSEKTNRQ-------LRIHELVVKHSSNASLV-VMSLPMPRK 1030
            .|       ...|.|:..|:..|.|..:|..       ..:::|:::.......| .:.||.|..
Zfish   849 EL-------ESEEGGVEADKFFSNSFPSNTSRVSDEYLQAVNKLILEQKLRPPAVRFLYLPRPPA 906

  Fly  1031 EAISAPLYMSWLEMLTSDMKCPVALARGNQTPVLT 1065
            :......|::.||:||.|:. |..|..| .|||:|
Zfish   907 DTSRYSDYLNQLELLTRDLG-PTLLIHG-VTPVIT 939

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NKCC	NP_730938.1	2a30	85..1068	CDD:273347	273/1075 (25%)
		DUF502	507..>643	CDD:294696	44/139 (32%)
		SLC12	651..1068	CDD:281515	98/465 (21%)
zgc:153039	XP_021337145.1	SLC12	12..933	CDD:332077	263/1056 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910