Protein Alignment NKCC and CG12773

DIOPT Version :10

• Sequence 1: NP_730938.1
• Gene: NKCC / 40663
• FlyBaseID: FBgn0051547
• Length: 1068
• Species: Drosophila melanogaster
• Sequence 2: NP_569905.1
• Gene: CG12773 / 31082
• FlyBaseID: FBgn0024365
• Length: 712
• Species: Drosophila melanogaster
• Alignment Length: 598
• Identity: 139/598 - (23%)
• Similarity: 245/598 - (40%)
• Gaps: 175/598 - (29%)

  Fly   141 GVLIPCLLNIWGVMLFLRLSWVVAESGILQSLIIITISAVVCVITTLSLSAISTNGEVKGGGVYF 205
            ||...||:|::||::|||..|:||::|||.:::||..:.|:.:::.||...|.....|:.|||||
  Fly    97 GVFTSCLINVFGVIVFLRSGWIVAQAGILNAVLIIFCTVVIALVSVLSAIGICERCRVESGGVYF 161

  Fly   206 IISRSLGPEFGASVGVVFAFANAVSASMNTIGFCESLNVLLKNNDLKIVDNGINDIR--IVGSIT 268
            :|:.:||..||.::|:::.|..||..::|.:||.||:..|:          |:...:  |.|..|
  Fly   162 LIAHTLGSRFGGALGLLYCFGQAVGCALNVMGFGESMAGLV----------GLEGSKWAIRGFAT 216

  Fly   269 VLVLILIC--CVGMEWETKAQNFLIVTIVLAIFNFLIGAAIGPQGNEEQISRGFVGFSWATLKEN 331
            ..||:|.|  ..|::|..|.|..|::.::::..:|::|:.      ..:.|.||.|::.....||
  Fly   217 AAVLLLGCINVAGVKWVIKLQFILLMILLISALDFMVGSF------TSEASGGFNGWASGNFVEN 275

  Fly   332 FGSDYRYAEGVNHDFFSVFAIFFPSVTGIQAGANICGDLKDAGAAIPKGTFWSLLISMSSYALFV 396
            ...  :|.:|  :.:|.||.:|||:|||:.:|.|:.|||:.....||.||..:...|...|.:||
  Fly   276 LWP--KYDDG--YSWFRVFGVFFPTVTGVLSGINMSGDLRAPSTDIPNGTLAAFGTSTFLYLVFV 336

  Fly   397 LFAGGAAVRDASGIPADLVNGTIVSSELPCMATGNCTWGLFNSYEMMQEMSLWGPLIYAGCFAAT 461
            ||.|....|..                            |:..|.:..::|....|:.||.:.::
  Fly   337 LFLGATCQRSF----------------------------LYTDYMISVKVSAVHFLLLAGIYVSS 373

  Fly   462 LSTALTNLLSVPRLVQALGIDQIYPGLIFFSKPYGKHGEPYRGYVLTFFITTGFLLIGELNLIAP 526
            :|:.|..:...||::|::..:.:.||:....|..|.:..|.....:...:|..|:::|::|.:||
  Fly   374 MSSCLGAMYGTPRVLQSIAKESVIPGIDILGKGRGPNKVPLYAMAIVALVTVTFIIVGDINFLAP 438

  Fly   527 LISTFYLASYALINFCTF----------------------------------------------- 544
            :::..:|.:||.|::..|
  Fly   439 IVTMPFLLTYACIDYAYFALAQTFDIQEQREERFRIQASSPSYETRRYGSVSDTGNDLDLLFPDR 503

  Fly   545 ----------------------------------------------------------------- 544
                                                                             
  Fly   504 VRHKNLQSPQNSPLHQTVPLEFDNEGPSTSNQAQSSERRTGHEADTTLAVEQAVAQAGVEQDQGD 568

  Fly   545 HAAFVKPLGWRPTFK---------YYNAWLSLFGFAMCVAIMFLINYVAAIITFGIIFALYLVVM 600
            .|..:.|:  ||...         |.|.|.||.|....:.:|.|:|:..|:..|.::|.::..|.
  Fly   569 EAEPIAPI--RPPIHSKTKNWYSGYCNRWASLLGAFTKLLVMLLVNWYYALTCFLVVFVVWFYVG 631

  Fly   601 YRKPEANWGSTTQ 613
            ...|....|.|.:
  Fly   632 TANPAVKPGLTAE 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NKCC	NP_730938.1	AA_permease_2	85..1068	CDD:459263	139/598 (23%)
CG12773	NP_569905.1	AA_permease_2	88..>456	CDD:459263	118/406 (29%)