DRSC/TRiP Functional Genomics Resources

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Protein Alignment NKCC and Slc7a1

DIOPT Version :9

Sequence 1:NP_730938.1 Gene:NKCC / 40663 FlyBaseID:FBgn0051547 Length:1068 Species:Drosophila melanogaster
Sequence 2:NP_037243.2 Gene:Slc7a1 / 25648 RGDID:3716 Length:624 Species:Rattus norvegicus


Alignment Length:470 Identity:101/470 - (21%)
Similarity:167/470 - (35%) Gaps:169/470 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   184 ITTLSLSAISTNGEVKGGGVYFI---ISR-SLGP---------------------EFGA------ 217
            :.|..|.|:.. |...|.|||.:   ::| :.||                     ||||      
  Rat    32 LNTYDLVALGV-GSTLGAGVYVLAGAVARENAGPAIVISFLIAALASVLAGLCYGEFGARVPKTG 95

  Fly   218 --------SVGVVFAF-----------------ANAVSASMN-----TIG-FCE---SLN---VL 245
                    :||.::||                 |.|.||:.:     .|| |..   :||   ||
  Rat    96 SAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGKPIGEFSRQHMALNAPGVL 160

  Fly   246 LKNNDL----------KIVDNGINDIRIVGSITVLVLILICCVGMEWETKAQNFLIVTIVLAIFN 300
            .:..|:          .::..|:.:..:|..|...:.:|:.|           |::|:      .
  Rat   161 AQTPDIFAVIIIIILTGLLTLGVKESAMVNKIFTCINVLVLC-----------FIMVS------G 208

  Fly   301 FLIGAAIGPQGNEEQISRGFVGFSWATLKENFGSDYRYAEGVNHDFFSVFAIFFP-SVTGIQAGA 364
            |:.|:....|..|.:.|         .|..|..::.:|.||.          |.| ..:|:.:||
  Rat   209 FVKGSIENWQLTENKSS---------PLCGNNDTNVKYGEGG----------FMPFGFSGVLSGA 254

  Fly   365 NIC--------------GDLKDAGAAIPKGTFWSLLISMSSYALFVLFAGGAAVRDASGIPADLV 415
            ..|              .::|:...|||.|...||||...:|               .|:.|.| 
  Rat   255 ATCFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAY---------------FGVSAAL- 303

  Fly   416 NGTIVSSELP--CMATGNCTWGLFNSYEMMQEMSLWGPLIYAGCFAATLSTALTNLLSVPRLVQA 478
              |::   :|  |:.|.:...|.| .|...:|...   .:..|...|..::.|.::..:||::.|
  Rat   304 --TLM---MPYFCLDTDSPLPGAF-KYRGWEEAKY---AVAVGSLCALSTSLLGSMFPMPRVIYA 359

  Fly   479 LGIDQIYPGLI--FFSKPYGKHGEPYRGYVLTFFITTGFLLIGELNLIAPLISTFYLASYALINF 541
            :..|    ||:  |.:|...:...|....|.:..|......:.||..:..|:|...|.:|:|:  
  Rat   360 MAED----GLLFKFLAKINDRTKTPIIATVTSGAIAAVMAFLFELKDLVDLMSIGTLLAYSLV-- 418

  Fly   542 CTFHAAFVKPLGWRP 556
                ||.|..|.::|
  Rat   419 ----AACVLVLRYQP 429

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NKCCNP_730938.1 2a30 85..1068 CDD:273347 101/470 (21%)
DUF502 507..>643 CDD:294696 13/50 (26%)
SLC12 651..1068 CDD:281515
Slc7a1NP_037243.2 2A0303 4..605 CDD:273330 101/470 (21%)
AA_permease_C 553..603 CDD:290617
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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