Protein Alignment NKCC and F10E7.9

DIOPT Version :10

• Sequence 1: NP_730938.1
• Gene: NKCC / 40663
• FlyBaseID: FBgn0051547
• Length: 1068
• Species: Drosophila melanogaster
• Sequence 2: NP_495469.2
• Gene: F10E7.9 / 174167
• WormBaseID: WBGene00017350
• Length: 603
• Species: Caenorhabditis elegans
• Alignment Length: 597
• Identity: 150/597 - (25%)
• Similarity: 267/597 - (44%)
• Gaps: 108/597 - (18%)

  Fly   112 QGEAVDQSITIPEPEPEATGGHIKLGWIVGVLIPCLLNIWGVMLFLRLSWVVAESGILQSLIIIT 176
            |||..|.|..........|...:..|...||....::||:|:::||||.|:|..:|:..|::::.
 Worm    23 QGETADSSQLPWWQRTILTKDKVLFGTWDGVFATVMVNIFGIIVFLRLGWIVGTAGVANSILLLG 87

  Fly   177 ISAVVCVITTLSLSAISTNGEVKGGGVYFIISRSLGPEFGASVGVVFAFANAVSASMNTIGFCES 241
            |...:.:||..|...|....::|.||:||::|..||.:.|.::|:::||..||:..:..:||.||
 Worm    88 ICTSLALITVFSAIGIVERCQIKSGGIYFLVSHVLGHQIGGAIGIIYAFGQAVATGLVAVGFGES 152

  Fly   242 LNVLLKNNDLKIVDNGINDIRIVGSITVLVLILICCVGMEWETKAQNFLIVTIVLAIFNFLIGAA 306
            :..|.: ::.||:..||      ..:|::||..:...|:.|..:.|..|::||.||:.:|:.||.
 Worm   153 VAHLFE-SESKIMIKGI------AILTLMVLTAVNTAGVTWVVRLQIVLLLTIALAVTDFIFGAL 210

  Fly   307 IGPQGNEEQISRGFVGFSWATLKENFGSDYRYAEGVN------------HDFFSVFAIFFPSVTG 359
            ...:...     |...||...::.|..|.|   |.||            ..||:||.:||.:..|
 Worm   211 FSSEPES-----GVFRFSSERIRVNADSHY---EAVNCSIIGIPRQIPEQSFFTVFGVFFANFLG 267

  Fly   360 IQAGANICGDLKDAGAAIPKGTFWSLLISMSSYALFVLFAGGAAVRDASGIPADLVNGTIVSSEL 424
            :.||.|:.|||||...:||.|...::.:|.:...:|::..||  |.|...:..|::
 Worm   268 VLAGVNMSGDLKDPHKSIPLGELSAVGVSSTICFIFIMILGG--VGDRMFLLCDVM--------- 321

  Fly   425 PCMATGNCTWGLFNSYEMMQEMSLWGPLIYAGCFAATLSTALTNLLSVPRLVQALGIDQIYPGLI 489
                             :.::::|.|.:...|.:..:||:.:.:||..||::|.:..:.|.|.|.
 Worm   322 -----------------ISEKVALTGIVFLVGLYVCSLSSTVGSLLGTPRVLQGIAEEGIIPCLN 369

  Fly   490 FFSKPYGKHGEPYRGYVLTFFITTGFLLIGELNLIAPLISTFYLASYALINF------------C 542
            ..::..|.:..|.....|...:.:.|:|:|:||.:|.|.:..:|.:||.:|:            .
 Worm   370 VLARGVGPNDNPVLAGYLLMGVASLFVLLGDLNQLAILSTMPFLITYAYVNYSYVSLAMSYDLAT 434

  Fly   543 TFHAAFVKPLGWRPTFK------------------------------------YYNAWLSLFGFA 571
            ..||..|:.:|:..|.|                                    :.|.::|..||.
 Worm   435 VQHADEVETVGYGSTNKMNDLNELFPERRDVNITSTEETETGIISQEATWYSMFSNRYVSFLGFL 499

  Fly   572 MCVAIMFLINYVAAIITFGIIFALYLVVMYRKPEANWGSTT--QAQQYKAALMAVHRLQNVSDHV 634
            :.:||:.||::..|:..|..:.|||..:....|....|.:|  ....:|....::..|::.:..:
 Worm   500 VNLAILLLIHFWFAVAHFVALIALYWYIGRVCPTCGPGISTFSLCHMFKTVFSSLDSLRSGATTI 564

  Fly   635 KNYHPQVLVLSG 646
            .   |:....||
 Worm   565 L---PETTFTSG 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NKCC	NP_730938.1	AA_permease_2	85..1068	CDD:459263	150/597 (25%)
F10E7.9	NP_495469.2	AA_permease_2	47..>557	CDD:459263	140/552 (25%)