Protein Alignment NKCC and LOC1276908

DIOPT Version :10

• Sequence 1: NP_730938.1
• Gene: NKCC / 40663
• FlyBaseID: FBgn0051547
• Length: 1068
• Species: Drosophila melanogaster
• Sequence 2: XP_316315.4
• Gene: LOC1276908 / 1276908
• VectorBaseID: AGAMI1_010553
• Length: 705
• Species: Anopheles gambiae
• Alignment Length: 590
• Identity: 147/590 - (24%)
• Similarity: 248/590 - (42%)
• Gaps: 166/590 - (28%)

  Fly   141 GVLIPCLLNIWGVMLFLRLSWVVAESGILQSLIIITISAVVCVITTLSLSAISTNGEVKGGGVYF 205
            ||...||:||:||::|||..|:|||:||:.:::|:..:..:.:::.||...|.....|:.|||||
Mosquito    89 GVFTSCLINIFGVIVFLRSGWIVAEAGIMHAILIVFCAVGIALVSVLSAVGICERCRVESGGVYF 153

  Fly   206 IISRSLGPEFGASVGVVFAFANAVSASMNTIGFCESLNVL--LKNNDLKIVDNGINDIRIVGSIT 268
            :|:.:||..||.|:|:::.|..||..::|.:||.||:..|  |:.|...|....|..:.::|.|.
Mosquito   154 LIAHTLGSRFGGSLGLLYCFGQAVGCALNVLGFGESIAGLVGLEGNQWAIRGFAIAAVLLLGVIN 218

  Fly   269 VLVLILICCVGMEWETKAQNFLIVTIVLAIFNFLIGAAIGPQGNEEQISRGFVGFSWATLKENFG 333
            |        .|::|..|.|..|::.|:::..:|::|:.||     |....||.|:....:..|..
Mosquito   219 V--------AGVKWVVKLQFALLIVILMSALDFMVGSFIG-----EAPEHGFDGWGSGNMGLNLW 270

  Fly   334 SDYRYAEGVNHDFFSVFAIFFPSVTGIQAGANICGDLKDAGAAIPKGTFWSLLISMSSYALFVLF 398
            |  .|.||.:  :|:||.:|||::|||.:|.|:.|||:.....||.||..:|..|...|.:|:||
Mosquito   271 S--AYTEGTS--WFTVFGVFFPTITGILSGINMSGDLRAPSTDIPNGTLAALSTSTFLYMVFILF 331

  Fly   399 AGGAAVRDASGIPADLVNGTIVSSELPCMATGNCTWGLFNSYEMMQEMSLWGPLIYAGCFAATLS 463
            .|....|.                            .|...|::..::|....|:.||.:.:::|
Mosquito   332 LGATCQRS----------------------------HLLTDYQIAVQVSAVEFLLLAGIYVSSMS 368

  Fly   464 TALTNLLSVPRLVQALGIDQIYPGLIFFSKPYGKHGEPYRGYVLTFFITTGFLLIGELNLIAPLI 528
            :.|..:...||::|::..:.:.||:....|..|.:..|.....:...:||.|::||::|.:||::
Mosquito   369 SCLGAMYGTPRVLQSIANENVIPGIGKLGKGRGPNKVPLYAMAVVAGVTTTFIIIGDINTLAPIV 433

  Fly   529 STFYLASYALINFCTFHAAFV-------------------------------------------- 549
            :..:|.:||.|::..|..|..
Mosquito   434 TMPFLLTYACIDYSYFALAQTFDIQNNREERFRIQAQSPLYETRNYGATGDYHENNDLDQLFPER 498

  Fly   550 ---KPLGW--------------------------------------------------------- 554
               |.||.
Mosquito   499 TRHKNLGTPSNSPQHVPSNAATSARSQQPNGIPHSSSITSADSEVVFRDGTNSANNANSVSEADD 563

  Fly   555 ------RP-----TFKYY----NAWLSLFGFAMCVAIMFLINYVAAIITFGIIFALYLVVMYRKP 604
                  ||     |..:|    |.|.||.|..:.:.:|.|:::|.|:|..|.:|.::..|....|
Mosquito   564 EPIAPIRPPIHSKTKNWYSGFCNRWASLIGAGIKILVMLLVSWVYALICIGTVFIVWFYVGTANP 628

  Fly   605 EANWG 609
            ....|
Mosquito   629 AVKPG 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NKCC	NP_730938.1	AA_permease_2	85..1068	CDD:459263	147/590 (25%)
LOC1276908	XP_316315.4	AA_permease_2	41..>449	CDD:459263	123/404 (30%)