Protein Alignment NKCC and Slc7a1

DIOPT Version :9

• Sequence 1: NP_730938.1
• Gene: NKCC / 40663
• FlyBaseID: FBgn0051547
• Length: 1068
• Species: Drosophila melanogaster
• Sequence 2: NP_001288353.1
• Gene: Slc7a1 / 11987
• MGIID: 88117
• Length: 622
• Species: Mus musculus
• Alignment Length: 469
• Identity: 103/469 - (21%)
• Similarity: 168/469 - (35%)
• Gaps: 169/469 - (36%)

  Fly   184 ITTLSLSAISTNGEVKGGGVYFI---ISR-SLGP---------------------EFGA------ 217
            :.|..|.|:.. |...|.|||.:   ::| :.||                     ||||
Mouse    32 LNTYDLVALGV-GSTLGAGVYVLAGAVARENAGPAIVISFLIAALASVLAGLCYGEFGARVPKTG 95

  Fly   218 --------SVGVVFAF-----------------ANAVSASMN-----TIG-FCE---SLN---VL 245
                    :||.::||                 |.|.||:.:     .|| |..   :||   ||
Mouse    96 SAYLYSYVTVGELWAFITGWNLILSYIIGTSSVARAWSATFDELIGKPIGEFSRQHMALNAPGVL 160

  Fly   246 LKNNDLKIVDNGINDIRIVGSITVLVLILICCVGMEWETKAQNFLIVTIVLAIFNFLIGAAIGPQ 310
            .:..|:..|            |.:::|..:..:|:: |:...|.:...|.:.:..|::.:
Mouse   161 AQTPDIFAV------------IIIIILTGLLTLGVK-ESAMVNKIFTCINVLVLCFIVVS----- 207

  Fly   311 GNEEQISRGFVGFS---WATLKENFG-----SDYRYAEGVNHDFFSVFAIFFP-SVTGIQAGANI 366
                    |||..|   |...::||.     ::.:|.||.          |.| ..:|:.:||..
Mouse   208 --------GFVKGSIKNWQLTEKNFSCNNNDTNVKYGEGG----------FMPFGFSGVLSGAAT 254

  Fly   367 C--------------GDLKDAGAAIPKGTFWSLLISMSSYALFVLFAGGAAVRDASGIPADLVNG 417
            |              .::|:...|||.|...||||...:|     |...||:  ...:|...::
Mouse   255 CFYAFVGFDCIATTGEEVKNPQKAIPVGIVASLLICFIAY-----FGVSAAL--TLMMPYFCLD- 311

  Fly   418 TIVSSELPCMATGNCTWGLFNSYEMMQEMSLWGPLIYA---GCFAATLSTALTNLLSVPRLVQAL 479
              :.|.||         |.|....       |....||   |...|..::.|.::..:||::.|:
Mouse   312 --IDSPLP---------GAFKHQG-------WEEAKYAVAIGSLCALSTSLLGSMFPMPRVIYAM 358

  Fly   480 GIDQIYPGLI--FFSKPYGKHGEPYRGYVLTFFITTGFLLIGELNLIAPLISTFYLASYALINFC 542
            ..|    ||:  |.:|...:...|....|.:..|......:.||..:..|:|...|.:|:|:
Mouse   359 AED----GLLFKFLAKINNRTKTPVIATVTSGAIAAVMAFLFELKDLVDLMSIGTLLAYSLV--- 416

  Fly   543 TFHAAFVKPLGWRP 556
               ||.|..|.::|
Mouse   417 ---AACVLVLRYQP 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NKCC	NP_730938.1	2a30	85..1068	CDD:273347	103/469 (22%)
		DUF502	507..>643	CDD:294696	13/50 (26%)
		SLC12	651..1068	CDD:281515
Slc7a1	NP_001288353.1	2A0303	4..603	CDD:273330	103/469 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910