DRSC/TRiP Functional Genomics Resources

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Protein Alignment ksr and Map3k9

DIOPT Version :9

Sequence 1:NP_001287177.1 Gene:ksr / 40660 FlyBaseID:FBgn0015402 Length:966 Species:Drosophila melanogaster
Sequence 2:XP_038968662.1 Gene:Map3k9 / 500690 RGDID:1562149 Length:1140 Species:Rattus norvegicus


Alignment Length:375 Identity:100/375 - (26%)
Similarity:149/375 - (39%) Gaps:98/375 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   652 DSTEDGDSGQWR-----------QNSIS---------------------LKEWDIPYGDLLLLER 684
            ||...||.|.|.           .|.::                     ::..:|.:.:|.|.|.
  Rat    78 DSQVSGDEGWWTGQLNQRVGIFPSNYVTPRSAFSSRCQPGTEDPSCYPPIQLLEIDFAELTLEEI 142

  Fly   685 IGQGRFGTVHRALWHGD-VAVKLLNEDYLQD-EHMLETFRSEVANFKNTRHENLVLFMGACMNPP 747
            ||.|.||.|:||.|.|| ||||....|..:| ...:|..|.|...|...:|.|::...|.|:..|
  Rat   143 IGIGGFGKVYRAFWVGDEVAVKAARHDPDEDISQTIENVRQEAKLFAMLKHPNIIALRGVCLKEP 207

  Fly   748 YLAIVTSLCKGNTLYTYIHQRREKFAMNRTLLI--AQQIAQGMGYLHAREI---IHKDLRTKNI- 806
            .|.:|....:|..|...:..:|    :...:|:  |.|||:||.|||...|   ||:||::.|. 
  Rat   208 NLCLVMEFARGGPLNRVLSGKR----VPPDILVNWAVQIARGMNYLHDEAIVPVIHRDLKSSNSE 268

  Fly   807 -----------------------FIENGKVI-----ITDFGL----FSSTKLLYCDMGLGVPHNW 839
                                   .:|||.:.     ||||||    ..:||     |.....:.|
  Rat   269 CGELGWGEQHSLSLRLCEVLILQKVENGDLSNKTLKITDFGLAREWHRTTK-----MSAAGTYAW 328

  Fly   840 LCYLAPELIRALQPEKPRGECLEFTPYSDVYSFGTVWYELICGEFTFKDQPAESIIWQVGRGMKQ 904
               :|||:|||..          |:..|||:|:|.:.:||:.||..|:.....::.:  |..|.:
  Rat   329 ---MAPEVIRASM----------FSKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAY--GVAMNK 378

  Fly   905 SLANLQS--GRDVKDLLMLCWTYEKEHRPQFARLLSLLEHLPKKRLARSP 952
            ....:.|  ......|:..||..:...||.|:.:|..|..:.:......|
  Rat   379 LALPIPSTCPEPFAKLMEDCWNPDPHSRPSFSSILDQLTTIEESGFFEMP 428

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ksrNP_001287177.1 KSR1-SAM 33..166 CDD:290277
C1_1 368..419 CDD:278556
PK_KSR 678..946 CDD:270965 91/309 (29%)
Pkinase_Tyr 679..940 CDD:285015 90/302 (30%)
Map3k9XP_038968662.1 SH3_MLK1-3 49..106 CDD:212992 7/27 (26%)
STKc_MLK1 130..419 CDD:271047 92/312 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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