Protein Alignment ksr and ksr1

DIOPT Version :9

• Sequence 1: NP_001287177.1
• Gene: ksr / 40660
• FlyBaseID: FBgn0015402
• Length: 966
• Species: Drosophila melanogaster
• Sequence 2: XP_031751648.1
• Gene: ksr1 / 100494230
• XenbaseID: XB-GENE-1004628
• Length: 885
• Species: Xenopus tropicalis
• Alignment Length: 1021
• Identity: 314/1021 - (30%)
• Similarity: 457/1021 - (44%)
• Gaps: 253/1021 - (24%)

  Fly    33 LVIIQDMIDLSANHLEGLRTQCA-----------ISSTLTQQEIRC-------LESKLVRYFSEL 79
            |:::..::..:|...:|.:..||           .|.|.|..::|.       .::||:.|.|:.
 Frog    18 LIVMYSLLCSNAASFKGQKAMCASWLEKELELILTSETNTILKLRFWSPHLWQQKAKLINYISKQ 82

  Fly    80 LLAKMRLNERIPANGLVPHTTGNEL-------RQWLRVVGLSQGTLTACLARLTTLEQSLRLSDE 137
            |..|:.          |||....|:       ..||..:.:....:......| ||:..|.|::.
 Frog    83 LQCKLH----------VPHVERTEILNSYPRVSDWLHTISVRNEVVHKVSEEL-TLDALLELNEL 136

  Fly   138 EIRQLLADSPSQREEEELRRLTRAMQNLRKCMESLESGTAASNNDPEQWHWDSWDRPTHIHRGSV 202
            ::::.:....:  ..||..||..|:..|:|        .|.|..|.:...|:    |..:.:.|.
 Frog   137 KVKETMKKCGA--NTEECSRLNGALTCLKK--------LARSGGDMKDTLWN----PPEMRKESS 187

  Fly   203 GNIGLGNNS---------TASPRTHHRQHGVKGKNSALANSTNF-KSGRQSPSATEE------LN 251
            ..:....:|         :..|:|:..|     ..|...::..| :|..|.|....|      .:
 Frog   188 SQVPSDISSPVGAAWTLNSQPPKTNSHQ-----PRSISVSAIPFSESSSQGPYIYAENLQDPFSS 247

  Fly   252 STQGSQLTL------TLTPSPPNSPFTPSSGLSSSLNGTPQRSRGTPPPARK-HQTLL------- 302
            ||..|:|||      |:||     |.||.  |..::...|.|:  .|||.|| .|.||
 Frog   248 STPISRLTLRTPHGFTITP-----PTTPQ--LKRAIKLKPPRT--PPPPGRKVFQQLLPNFSTLK 303

  Fly   303 -SQSHVQVDGEQLARNRLPTDPS-----PDSHSSTSSDIFVDPNTNASSGGSSSNVLMVPCSPGV 361
             |:||     |....||:...||     |..                              ||.:
 Frog   304 RSKSH-----ESQLGNRIDEVPSLKFDLPQG------------------------------SPQM 333

  Fly   362 GHVGMGHAIKHRFTKALGFMATCTLCQKQVFHRWMKCTDCKYICHKSCAPHVPPSCGLPREYVDE 426
            ....:|.::.|||:........|.:|||.:.. .:||..||..||..|.... |||.:....:.:
 Frog   334 VRRDIGLSVTHRFSTKSWLSQMCHVCQKSMMF-GVKCKHCKLKCHNKCTKDA-PSCRISFLPIAK 396

  Fly   427 FRH-------IKEQGGYASLPHVHGAAKGSPLVKKSTLGKPLHQ---QHGDSSSPSSSCTSSTPS 481
            .|.       |..|....:.||.....|.  |.||.      |.   .|.||||..||.||||||
 Frog   397 IRRTESVPSDINNQVDRPAEPHFGTLPKA--LTKKE------HSPAINHLDSSSNPSSTTSSTPS 453

  Fly   482 SPALFQQRERELDQAGSSSSANLLPTPSLGKHQPSQFNFPNVTVTSSGGSGGVSLISNEPVPEQ- 545
            |||.|        |:.:.|||...|.||....:.|:||||           ....|.:.   :|
 Frog   454 SPAPF--------QSSNPSSAITPPNPSPIGPRDSRFNFP-----------AAYYIQHR---QQF 496

  Fly   546 -FPTAPATANGGLDSLVSSSNGHMSSLIGSQTSNASTAATLTGSLVNSTTTTSTCSFFPRKLSTA 609
             ||....||              .:|.:...:.|:|..|.:...:...              ..|
 Frog   497 IFPEVSVTA--------------QASHVSETSENSSAEAEMETDVAEE--------------QEA 533

  Fly   610 GVDKRTPFTSEYTDTHKSN---DSDKTVSLSGSASTDSDRTPVRVDSTEDGDSGQWR-------- 663
            .|:::        |.:||.   |.|:...|..|..|                ||.:|
 Frog   534 EVEEQ--------DANKSEPEYDDDELDELPNSRYT----------------SGTFRGMIIRKAS 574

  Fly   664 QNSISLKEWDIPYGDLLLLERIGQGRFGTVHRALWHGDVAVKLLNEDYLQDEHMLETFRSEVANF 728
            |.|:.|:|||||:..:.|.|.|||||:|.|.|..|||:||::||..|....:| |:.|:.||.|:
 Frog   575 QTSVYLQEWDIPFEQIELGELIGQGRWGKVFRGKWHGEVAIRLLEIDGNNQDH-LKLFKKEVMNY 638

  Fly   729 KNTRHENLVLFMGACMNPPYLAIVTSLCKGNTLYTYIHQRREKFAMNRTLLIAQQIAQGMGYLHA 793
            :.|||||:||||||||:||:|||:||.|||.|||:::...:....:|:|..|||:|.:|||||||
 Frog   639 RQTRHENVVLFMGACMHPPHLAIITSFCKGRTLYSFVRDPKTSLDINKTRQIAQEIIKGMGYLHA 703

  Fly   794 REIIHKDLRTKNIFIENGKVIITDFGLFSSTKLLY---CDMGLGVPHNWLCYLAPELIRALQPEK 855
            :.|:||||::||:|.|||||:|||||||..:.::.   .:..|.:.|:||||||||::|.:.|.|
 Frog   704 KGIVHKDLKSKNVFYENGKVVITDFGLFGISGVVQEGRRENELKLSHDWLCYLAPEIVREMTPGK 768

  Fly   856 PRGE-CLEFTPYSDVYSFGTVWYELICGEFTFKDQPAESIIWQV--GRGMKQSLANLQSGRDVKD 917
              || .|.|:..:|:|:|||:||||...::..|.|.||::|||:  |.||||.|:.:..|::|.:
 Frog   769 --GEDTLPFSKAADIYAFGTIWYELQARDWPLKRQAAEALIWQIGSGEGMKQVLSTISLGKEVTE 831

  Fly   918 LLMLCWTYEKEHRPQFARLLSLLEHLPKKRLARSPSHPVNLSRSAE 963
            :|..||.::...||.|..|:.:||.|||  |.|..|||.:..:||:
 Frog   832 ILAACWAFDVNERPSFTLLMDMLEKLPK--LNRRLSHPGHFWKSAD 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ksr	NP_001287177.1	KSR1-SAM	33..166	CDD:290277	31/157 (20%)
		C1_1	368..419	CDD:278556	17/50 (34%)
		PK_KSR	678..946	CDD:270965	135/273 (49%)
		Pkinase_Tyr	679..940	CDD:285015	131/266 (49%)
ksr1	XP_031751648.1	KSR1-SAM	18..163	CDD:404435	31/157 (20%)
		C1_KSR1	342..388	CDD:410422	16/47 (34%)
		STKc_KSR1	589..867	CDD:271054	139/282 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	287	1.000	Domainoid score	I1560
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	453	1.000	Inparanoid score	I1556
OMA	1	1.010	-	-		QHG45551
OrthoDB	1	1.010	-	-		D146946at33208
OrthoFinder	1	1.000	-	-		FOG0002339
OrthoInspector	1	1.000	-	-		otm48893
Panther	1	1.100	-	-	LDO	PTHR23257
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1770
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080