DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment LYL1 and CG33557

DIOPT Version :9

Sequence 1:	NP_005574.2	Gene:	LYL1 / 4066	HGNCID:	6734	Length:	280	Species:	Homo sapiens
Sequence 2:	NP_001014730.1	Gene:	CG33557 / 3346145	FlyBaseID:	FBgn0053557	Length:	150	Species:	Drosophila melanogaster

Alignment Length:	110	Identity:	38/110 - (34%)
Similarity:	51/110 - (46%)	Gaps:	31/110 - (28%)

- Green bases have known domain annotations that are detailed below.

Human   130 KRRPSHCELDLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRL 194
            :|||..           ||:      |:|||:|..|||.|:..||.|:||.|.:|||||.|::||
  Fly    58 RRRPPR-----------QKI------NARERYRTFNVNSAYEALRNLIPTEPMNRKLSKIEIIRL 105

Human   195 AMKYIGFLVRLLRDQAAALAAGPTPPGPRKRP--VHRVPDDGARR 237
            |..||..|...|.            .|...:|  :|:...:|..|
  Fly   106 ASSYITHLSSTLE------------TGTECQPCLLHKYESEGITR 138

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
LYL1	NP_005574.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..60
		HLH	156..208	CDD:197674	28/51 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	214..280		5/26 (19%)
CG33557	NP_001014730.1	HLH	67..119	CDD:197674	28/63 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810