DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snr1 and SNF5

DIOPT Version :9

Sequence 1:	NP_730935.1	Gene:	Snr1 / 40657	FlyBaseID:	FBgn0011715	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_009848.4	Gene:	SNF5 / 852592	SGDID:	S000000493	Length:	905	Species:	Saccharomyces cerevisiae

Alignment Length:	261	Identity:	90/261 - (34%)
Similarity:	137/261 - (52%)	Gaps:	38/261 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 VPQATPINRNRVHTKKVRTFPMCFDDTDPTASLENAAQKECLVPIRLDMELEGQK--LRDTFTWN 191
            :||....||......|::.:....::|           .|.||||||:.:.:..:  ||||..||
Yeast   427 IPQVEVGNRKHYLEDKLKVYKQAMNET-----------SEQLVPIRLEFDQDRDRFFLRDTLLWN 480

  Fly   192 KNESMITPEQFAEVLCDDL---DLNPLPFVPAIAQAIRQQIEAFPNDPPI-LEET----CDQRVI 248
            ||:.:|..|.|.:.:..|.   |......:..|.|:|::||:.|..:|.| |.:.    .|.|:.
Yeast   481 KNDKLIKIEDFVDDMLRDYRFEDATREQHIDTICQSIQEQIQEFQGNPYIELNQDRLGGDDLRIR 545

  Fly   249 VKLNIHVGNTSLVDQVEWDMSEKNNNPEEFAIKLCAELGLGGEFVTAIAYSIRGQLSWHCRT--- 310
            :||:|.||...|:||.|||:|..:|.|||||..:|.||.|.||||||||:|||.|:..:.::
Yeast   546 IKLDIVVGQNQLIDQFEWDISNSDNCPEEFAESMCQELELPGEFVTAIAHSIREQVHMYHKSLAL 610

  Fly   311 --YAFSEA------------PLSTIDVPFRNPSDADAWAPFLETLTDAEMEKKIRDQDRNTRRMR 361
              |.|..:            |..|:|..:|..:::..:.|.|..::.||:|:..:|:||:|||.|
Yeast   611 LGYNFDGSAIEDDDIRSRMLPTITLDDVYRPAAESKIFTPNLLQISAAELERLDKDKDRDTRRKR 675

  Fly   362 R 362
            |
Yeast   676 R 676

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snr1	NP_730935.1	WH_NTD_SMARCB1	5..92	CDD:411036
Snr1	NP_730935.1	SNF5	165..348	CDD:398495	75/209 (36%)
SNF5	NP_009848.4	SNF5	452..662	CDD:398495	76/220 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345007
Domainoid	1	1.000	90	1.000	Domainoid score	I1779
eggNOG	1	0.900	-	-		E1_KOG1649
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1514
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002902
OrthoInspector	1	1.000	-	-		oto99405
orthoMCL	1	0.900	-	-		OOG6_103095
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1364
SonicParanoid	1	1.000	-	-		X1914
TreeFam	1	0.960	-	-
	11	10.580