DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Snr1 and smarcb1

DIOPT Version :9

Sequence 1:	NP_730935.1	Gene:	Snr1 / 40657	FlyBaseID:	FBgn0011715	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_001006819.1	Gene:	smarcb1 / 448543	XenbaseID:	XB-GENE-493598	Length:	378	Species:	Xenopus tropicalis

Alignment Length:	377	Identity:	258/377 - (68%)
Similarity:	301/377 - (79%)	Gaps:	8/377 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAL-QTYGDKPVAFQLEEGGEYYYVGSEVGNYMRHFRGILYKKYPGMTRIVLSNEERKRLAES-- 62
            ||| :|:|.|||.|||||.||||.:|||||||:|.|||.|||:||.:.|.:.:.||||::..|
Frog     3 MALSKTFGQKPVKFQLEEDGEYYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIVASSH 67

  Fly    63 GLSSH---ILASSVSLLRAVEVDDIMAGNDEKYRAVSVNTSDTPVPRESKSKKQPQYVPTMPNSS 124
            |...|   .||:||:||:|.||::|:.||||||:|||::|......||.|:|:..|:|||:||||
Frog    68 GKKYHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQWVPTLPNSS 132

  Fly   125 -HLDAVPQATPINRNRVHTKKVRTFPMCFDDTDPTASLENAAQKECLVPIRLDMELEGQKLRDTF 188
             ||||||.:|.|||||:...|.||||:||||.||....|||||.|.|||||||||::||||||.|
Frog   133 HHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENAAQSEVLVPIRLDMEIDGQKLRDAF 197

  Fly   189 TWNKNESMITPEQFAEVLCDDLDLNPLPFVPAIAQAIRQQIEAFPNDPPILEETCDQRVIVKLNI 253
            |||.||.::|||.|||:||||||||||.||||||.|||||||::|.| .|||:..|||||:||||
Frog   198 TWNMNEKLMTPEMFAEILCDDLDLNPLAFVPAIASAIRQQIESYPTD-SILEDQSDQRVIIKLNI 261

  Fly   254 HVGNTSLVDQVEWDMSEKNNNPEEFAIKLCAELGLGGEFVTAIAYSIRGQLSWHCRTYAFSEAPL 318
            ||||.|||||.|||||||.|:||:||:|||:||||||||||.||||||||||||.:||||||.||
Frog   262 HVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQKTYAFSENPL 326

  Fly   319 STIDVPFRNPSDADAWAPFLETLTDAEMEKKIRDQDRNTRRMRRLANTTTGW 370
            .|:::..||..|||.|.|.|||||||||||||||||||||||||||||...|
Frog   327 PTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snr1	NP_730935.1	WH_NTD_SMARCB1	5..92	CDD:411036	52/91 (57%)
Snr1	NP_730935.1	SNF5	165..348	CDD:398495	138/182 (76%)
smarcb1	NP_001006819.1	DNA-binding. /evidence=ECO:0000250\|UniProtKB:Q12824	1..106		60/102 (59%)
smarcb1	NP_001006819.1	SNF5	174..356	CDD:368157	138/182 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	196	1.000	Domainoid score	I3081
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2310
Inparanoid	1	1.050	511	1.000	Inparanoid score	I1283
OMA	1	1.010	-	-		QHG45849
OrthoDB	1	1.010	-	-		D343144at33208
OrthoFinder	1	1.000	-	-		FOG0002902
OrthoInspector	1	1.000	-	-		oto103275
Panther	1	1.100	-	-	LDO	PTHR10019
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1364
SonicParanoid	1	1.000	-	-		X1914
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110