Protein Alignment Snr1 and Smarcb1

DIOPT Version :10

• Sequence 1: NP_730935.1
• Gene: Snr1 / 40657
• FlyBaseID: FBgn0011715
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_035548.1
• Gene: Smarcb1 / 20587
• MGIID: 1328366
• Length: 385
• Species: Mus musculus
• Alignment Length: 386
• Identity: 254/386 - (65%)
• Similarity: 301/386 - (77%)
• Gaps: 20/386 - (5%)

  Fly     1 MAL-QTYGDKPVAFQLEEGGEYYYVGSEVGNYMRHFRGILYKKYPGMTRIVLSNEERKRLAESGL 64
            ||| :|:|.|||.||||:.||:|.:|||||||:|.|||.|||:||.:.|.:.:.||||::.   .
Mouse     4 MALSKTFGQKPVKFQLEDDGEFYMIGSEVGNYLRMFRGSLYKRYPSLWRRLATVEERKKIV---A 65

  Fly    65 SSH--------------ILASSVSLLRAVEVDDIMAGNDEKYRAVSVNTSDTPVPRESKSKKQPQ 115
            |||              .||:||:||:|.||::|:.||||||:|||::|......||.|:|:..|
Mouse    66 SSHGKKTKPNTKDHGYTTLATSVTLLKASEVEEILDGNDEKYKAVSISTEPPTYLREQKAKRNSQ 130

  Fly   116 YVPTMPNSS-HLDAVPQATPINRNRVHTKKVRTFPMCFDDTDPTASLENAAQKECLVPIRLDMEL 179
            :|||:|||| ||||||.:|.|||||:...|.||||:||||.||....|||:|.|.|||||||||:
Mouse   131 WVPTLPNSSHHLDAVPCSTTINRNRMGRDKKRTFPLCFDDHDPAVIHENASQPEVLVPIRLDMEI 195

  Fly   180 EGQKLRDTFTWNKNESMITPEQFAEVLCDDLDLNPLPFVPAIAQAIRQQIEAFPNDPPILEETCD 244
            :||||||.||||.||.::|||.|:|:||||||||||.||||||.|||||||::|.| .|||:..|
Mouse   196 DGQKLRDAFTWNMNEKLMTPEMFSEILCDDLDLNPLTFVPAIASAIRQQIESYPTD-SILEDQSD 259

  Fly   245 QRVIVKLNIHVGNTSLVDQVEWDMSEKNNNPEEFAIKLCAELGLGGEFVTAIAYSIRGQLSWHCR 309
            ||||:||||||||.|||||.|||||||.|:||:||:|||:||||||||||.||||||||||||.:
Mouse   260 QRVIIKLNIHVGNISLVDQFEWDMSEKENSPEKFALKLCSELGLGGEFVTTIAYSIRGQLSWHQK 324

  Fly   310 TYAFSEAPLSTIDVPFRNPSDADAWAPFLETLTDAEMEKKIRDQDRNTRRMRRLANTTTGW 370
            ||||||.||.|:::..||..|||.|.|.|||||||||||||||||||||||||||||...|
Mouse   325 TYAFSENPLPTVEIAIRNTGDADQWCPLLETLTDAEMEKKIRDQDRNTRRMRRLANTAPAW 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Snr1	NP_730935.1	WH_NTD_SMARCB1	5..92	CDD:411036	50/100 (50%)
		SNF5	165..348	CDD:428158	136/182 (75%)
Smarcb1	NP_035548.1	DNA-binding. /evidence=ECO:0000250|UniProtKB:Q12824	1..113		58/111 (52%)
		WH_NTD_SMARCB1	9..107	CDD:411036	50/100 (50%)
		SNF5	181..363	CDD:428158	136/182 (75%)
		2 X approximate tandem repeats	186..319		104/133 (78%)
		MYC-binding. /evidence=ECO:0000250|UniProtKB:Q12824	186..245		46/58 (79%)
		Interaction with PPP1R15A. /evidence=ECO:0000250|UniProtKB:Q12824	304..318		12/13 (92%)