DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Snr1 and snfc-5

DIOPT Version :9

Sequence 1:	NP_730935.1	Gene:	Snr1 / 40657	FlyBaseID:	FBgn0011715	Length:	370	Species:	Drosophila melanogaster
Sequence 2:	NP_001369845.1	Gene:	snfc-5 / 175571	WormBaseID:	WBGene00011111	Length:	381	Species:	Caenorhabditis elegans

Alignment Length:	369	Identity:	196/369 - (53%)
Similarity:	257/369 - (69%)	Gaps:	13/369 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 QTYGDKPVAFQLEEGGEYYYVGSEVGNYMRHFRGILYKKYPGMTRIVLSNEERKRLAESGLSSHI 68
            ||||.:|.:|.|:|.||.||:|||:|.|:|..||.||||||.:.|.|.:::::.:|.:..:|:..
Worm    10 QTYGPRPQSFSLDEAGERYYIGSEIGAYLRLHRGTLYKKYPLLWRKVATSDDKDKLKQIAMSNAF 74

  Fly    69 LASSVSLLRAVEVDDIMAGNDEKYRAVSVNTSDTPVPRESKSKKQPQYVP--------TMPNSSH 125
            |.:::.||||.|||:::.|::|||||.....|   .||...:.:.....|        ....|.|
Worm    75 LHTNIMLLRAHEVDELLDGSEEKYRAAGAAPS---TPRTEGASRTVAKTPATGWAGQQVTSGSHH 136

  Fly   126 LDAVPQATPINRNRVHTKKVRTFPMCFDDTDPTAS-LENAAQKECLVPIRLDMELEGQKLRDTFT 189
            |::||.:.||..:|...|. |......:|.:.:.. ::||.:.|.||||||||||:|.|||||||
Worm   137 LESVPCSCPIAHSRGRMKH-RELVYSAEDLEMSKRVMKNAEEGEDLVPIRLDMELDGIKLRDTFT 200

  Fly   190 WNKNESMITPEQFAEVLCDDLDLNPLPFVPAIAQAIRQQIEAFPNDPPILEETCDQRVIVKLNIH 254
            :||||.|||||..||::|:||||....|.|||..||.||:||....||:....||||.::||||:
Worm   201 FNKNEKMITPEMIAEIMCEDLDLPLAVFQPAITAAINQQLEASTEAPPLDVNICDQRAVLKLNIN 265

  Fly   255 VGNTSLVDQVEWDMSEKNNNPEEFAIKLCAELGLGGEFVTAIAYSIRGQLSWHCRTYAFSEAPLS 319
            |||.|||||.|||||:.||:||||:..:|.||||||||::.|||||||||.|:.|||||||:||:
Worm   266 VGNQSLVDQFEWDMSDPNNSPEEFSRNICKELGLGGEFMSGIAYSIRGQLQWNQRTYAFSESPLA 330

  Fly   320 TIDVPFRNPSDADAWAPFLETLTDAEMEKKIRDQDRNTRRMRRL 363
            |:|.|||..|:.::|.||||||||||:|||:|||||||||||||
Worm   331 TVDCPFRTSSEVESWGPFLETLTDAEIEKKMRDQDRNTRRMRRL 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Snr1	NP_730935.1	WH_NTD_SMARCB1	5..92	CDD:411036	39/86 (45%)
Snr1	NP_730935.1	SNF5	165..348	CDD:398495	119/182 (65%)
snfc-5	NP_001369845.1	WH_NTD_SMARCB1	11..98	CDD:411036	39/86 (45%)
snfc-5	NP_001369845.1	SNF5	176..359	CDD:398495	119/182 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163380
Domainoid	1	1.000	181	1.000	Domainoid score	I2076
eggNOG	1	0.900	-	-		E1_KOG1649
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2310
Inparanoid	1	1.050	380	1.000	Inparanoid score	I1193
Isobase	1	0.950	-	0	Normalized mean entropy	S1514
OMA	1	1.010	-	-		QHG45849
OrthoDB	1	1.010	-	-		D343144at33208
OrthoFinder	1	1.000	-	-		FOG0002902
OrthoInspector	1	1.000	-	-		oto17835
orthoMCL	1	0.900	-	-		OOG6_103095
Panther	1	1.100	-	-	LDO	PTHR10019
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1364
SonicParanoid	1	1.000	-	-		X1914
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790