Protein Alignment POLDIP2 and SMI1

DIOPT Version :10

• Sequence 1: NP_730934.1
• Gene: POLDIP2 / 40655
• FlyBaseID: FBgn0037329
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_011745.1
• Gene: SMI1 / 853144
• SGDID: S000003461
• Length: 505
• Species: Saccharomyces cerevisiae
• Alignment Length: 403
• Identity: 84/403 - (20%)
• Similarity: 136/403 - (33%)
• Gaps: 133/403 - (33%)

  Fly    94 WTARVYDRDLHNPGKISATTTTSANPTQQNRTKEASLRVKANTSASPTAATAQSADAPTSTAFET 158
            ||:.      |||.    ...|.::|..||....|...::. :..:|..|:.:..|.      :.
Yeast   100 WTSE------HNPD----LNATLSDPCTQNDITHAEEDLEV-SFPNPVKASFKIHDG------QE 147

  Fly   159 NAAESTGTTNLGTTSQVDPKEVKGKVQTFYQVLIDTRDCPYIRAQTEAVTFLGNQDSNRSLYAIP 223
            :....|||:.|                 ||...:.|.|  .:.|.|:|...:....:.||.   .
Yeast   148 DLESMTGTSGL-----------------FYGFQLMTLD--QVVAMTQAWRNVAKNLNKRSQ---Q 190

  Fly   224 GLDYVAHEDIMPYSSSEKSPLQHELFDKF-LTHAPD--ADPPFVGQDTLKAWQEKNHP-WLDMSD 284
            ||.:|.       |:...|.::....:|| |.:.||  :.||...|....      || |:.:
Yeast   191 GLSHVT-------STGSSSSMERLNGNKFKLPNIPDQKSIPPNAVQPVYA------HPAWIPL-- 240

  Fly   285 VHKETTENVRITVIPFYMGCRETPASSVYWWR----YCIRLENLGELSV----QLRERHWRI--- 338
            :......::.:.:.|   |.....|..:.:.|    ..:..||.||..:    .|...:|.:
Yeast   241 ITDNAGNHIGVDLAP---GPNGKYAQIITFGRDFDTKFVIAENWGEFLLSFANDLEAGNWYLVDD 302

  Fly   339 ----FSLSGTL---------------ETVRGR-GVVGQEPILSPR--------------LPAFQY 369
                ||..|.|               |.::.| .:..||.:.|.:              :||.|
Yeast   303 NDDYFSGDGELVFRDKKSNGPIQDYFEVLKRRTWIKYQENLRSQQQKSQPDTSLQEQKYVPASQ- 366

  Fly   370 SSHVSLQAPSGHMWGTFRLER---EDGYSFD---------CKIPPFSLESKPDDLGTPTPATPS- 421
             ..|:.:.||     |...|.   ||..|.|         .||    ::::|.:..|.|..|.|
Yeast   367 -KKVAAEQPS-----TLNAESIKGEDSGSADVQSVQDHESVKI----VKTEPSEAETTTVNTESL 421

  Fly   422 ---AHDKKRDDSD 431
               .|:.|.|:.|
Yeast   422 GQAEHEIKADNVD 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POLDIP2	NP_730934.1	YccV-like	72..258	CDD:445467	34/164 (21%)
		DUF525	289..407	CDD:470082	33/174 (19%)
SMI1	NP_011745.1	SMI1	93..313	CDD:443423	55/269 (20%)
		PTZ00121	<329..>501	CDD:173412	28/117 (24%)