DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment POLDIP2 and Poldip2

DIOPT Version :9

Sequence 1:	NP_730934.1	Gene:	POLDIP2 / 40655	FlyBaseID:	FBgn0037329	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_080665.1	Gene:	Poldip2 / 67811	MGIID:	1915061	Length:	368	Species:	Mus musculus

Alignment Length:	407	Identity:	219/407 - (53%)
Similarity:	259/407 - (63%)	Gaps:	79/407 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 QGGHPAAAWRQEAGGVSDQVSGVLNPPENCIT-RHLYR--------LAEVGRL-VDARDDRYETG 76
            :|..|..|    .||     :|.|.|.....| |||..        |..||.. |..::.:||||
Mouse    25 RGSRPLCA----VGG-----AGGLPPVATATTRRHLSSRNRAEGKVLETVGVFEVPKQNGKYETG 80

  Fly    77 QLFLHRIFGYRGVILFPWTARVYDRDLHNPGKISATTTTSANPTQQNRTKEASLRVKANTSASPT 141
            |||||.:||||||:||||.||:||||:                                     .
Mouse    81 QLFLHSVFGYRGVVLFPWQARLYDRDV-------------------------------------A 108

  Fly   142 AATAQSADAPTSTAFETNAAESTGTTNLGTTSQVDPKEVKGKVQTFYQVLIDTRDCPYI--RAQT 204
            :||.:.|:.|....                     .||||||..|:||||||.||||:|  |:||
Mouse   109 SATPEKAENPAGHG---------------------SKEVKGKTHTYYQVLIDARDCPHISQRSQT 152

  Fly   205 EAVTFLGNQDSNRSLYAIPGLDYVAHEDIMPYSSSEKSPLQHELFDKFLTHAPDADPPFVGQDTL 269
            ||||||.|.|.:|:||||||||||:||||:||:|:::.|:|||||::||.:.....||||.::||
Mouse   153 EAVTFLANHDDSRALYAIPGLDYVSHEDILPYTSTDQVPIQHELFERFLLYDQTKAPPFVARETL 217

  Fly   270 KAWQEKNHPWLDMSDVHKETTENVRITVIPFYMGCRETPASSVYWWRYCIRLENLGELSVQLRER 334
            :||||||||||::||||:|||||:|:||||||||.||...|.|||||||||||||....||||||
Mouse   218 RAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHVYWWRYCIRLENLDSDVVQLRER 282

  Fly   335 HWRIFSLSGTLETVRGRGVVGQEPILSPRLPAFQYSSHVSLQAPSGHMWGTFRLEREDGYSFDCK 399
            |||||||||||||||||||||:||:||...|||||||||||||.|||||||||.||.||..||.:
Mouse   283 HWRIFSLSGTLETVRGRGVVGREPVLSKEQPAFQYSSHVSLQASSGHMWGTFRFERPDGSHFDVR 347

  Fly   400 IPPFSLESKPDDLGTPT 416
            ||||||||..|:...|:
Mouse   348 IPPFSLESNKDEKTPPS 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
POLDIP2	NP_730934.1	YccV-like	72..258	CDD:294919	84/187 (45%)
POLDIP2	NP_730934.1	DUF525	308..390	CDD:282262	67/81 (83%)
Poldip2	NP_080665.1	YccV-like	74..200	CDD:294919	82/183 (45%)
Poldip2	NP_080665.1	DUF525	234..355	CDD:294703	96/120 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836775
Domainoid	1	1.000	145	1.000	Domainoid score	I4573
eggNOG	1	0.900	-	-		E1_COG2967
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9201
Inparanoid	1	1.050	410	1.000	Inparanoid score	I1852
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48062
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008192
OrthoInspector	1	1.000	-	-		oto94997
orthoMCL	1	0.900	-	-		OOG6_104714
Panther	1	1.100	-	-	LDO	PTHR14289
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4148
SonicParanoid	1	1.000	-	-		X6156
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790