DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment POLDIP2 and Fbxo3

DIOPT Version :9

Sequence 1:	NP_730934.1	Gene:	POLDIP2 / 40655	FlyBaseID:	FBgn0037329	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_997598.1	Gene:	Fbxo3 / 57443	MGIID:	1929084	Length:	480	Species:	Mus musculus

Alignment Length:	165	Identity:	51/165 - (30%)
Similarity:	78/165 - (47%)	Gaps:	29/165 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   289 TTENVRITVIPFYMGCRETPASSV----YWWRYCIRLE----NLGELSVQLRERHWRIFSLSGTL 345
            ||.::.::|...::    ...|||    |::.|.||:|    .|.|.:.||..|:|||.:..|.:
Mouse   280 TTGDITVSVSTSFL----PELSSVHPPHYFFTYRIRIEMSRDALPEKACQLDSRYWRITNAKGDV 340

  Fly   346 ETVRGRGVVGQEPILSP-RLPAFQYSSHVSLQAPSGHMWG--TFRLEREDGYSFDCKIPPF---- 403
            |.|:|.||||:.||:|| |:  ::|:|..:....||:|.|  ||.........|:..||.|
Mouse   341 EEVQGPGVVGEFPIISPGRI--YEYTSCTTFSTTSGYMEGYYTFHFLYFKDKVFNVAIPRFHMAC 403

  Fly   404 --------SLESKPDDLGTPTPATPSAHDKKRDDS 430
                    .||..||:............:::.|||
Mouse   404 PTFRVSIARLEMGPDEYEEMEEEAEEEEEEENDDS 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
POLDIP2	NP_730934.1	YccV-like	72..258	CDD:294919
POLDIP2	NP_730934.1	DUF525	308..390	CDD:282262	37/92 (40%)
Fbxo3	NP_997598.1	F-box-like	13..57	CDD:289689
		SMI1_KNR4	121..249	CDD:286436
		DUF525	279..404	CDD:294703	44/129 (34%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	419..463		3/20 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2967
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810