DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment POLDIP2 and poldip2

DIOPT Version :9

Sequence 1:	NP_730934.1	Gene:	POLDIP2 / 40655	FlyBaseID:	FBgn0037329	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_997879.1	Gene:	poldip2 / 100000398	ZFINID:	ZDB-GENE-030131-5881	Length:	376	Species:	Danio rerio

Alignment Length:	364	Identity:	211/364 - (57%)
Similarity:	251/364 - (68%)	Gaps:	68/364 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 GRLVDA--------RDDRYETGQLFLHRIFGYRGVILFPWTARVYDRDLHNPGKISATTTTSANP 119
            |::::|        :..:|||||||||.:|||||::||||.||:||||:       :..||.:.|
Zfish    67 GKILEAVGVFEALKQHGKYETGQLFLHSVFGYRGIVLFPWHARLYDRDV-------SPATTDSKP 124

  Fly   120 TQQNRTKEASLRVKANTSASPTAATAQSADAPTSTAFETNAAESTGTTNLGTTSQVDPKEVKGKV 184
                                                      :|||..:         ||||||:
Zfish   125 ------------------------------------------DSTGHGS---------KEVKGKM 138

  Fly   185 QTFYQVLIDTRDCPYI--RAQTEAVTFLGNQDSNRSLYAIPGLDYVAHEDIMPYSSSEKSPLQHE 247
            .|:|||||||||||:|  |:||||||||.|.|.:|:||||||||||:||||:||:|:|:.|:|||
Zfish   139 HTYYQVLIDTRDCPHISQRSQTEAVTFLANHDDSRALYAIPGLDYVSHEDILPYNSTEQVPIQHE 203

  Fly   248 LFDKFLTHAPDADPPFVGQDTLKAWQEKNHPWLDMSDVHKETTENVRITVIPFYMGCRETPASSV 312
            ||::||...|..:|||..:|||:||||||||||::||||:|||||:|:||||||||.||...|.|
Zfish   204 LFERFLMFNPSRNPPFTARDTLRAWQEKNHPWLELSDVHRETTENIRVTVIPFYMGMREAQNSHV 268

  Fly   313 YWWRYCIRLENLGELSVQLRERHWRIFSLSGTLETVRGRGVVGQEPILSPRLPAFQYSSHVSLQA 377
            |||||||||||||...|||||||||||||||||||||||||||:||:||...|||||||||||||
Zfish   269 YWWRYCIRLENLGNEVVQLRERHWRIFSLSGTLETVRGRGVVGKEPVLSREQPAFQYSSHVSLQA 333

  Fly   378 PSGHMWGTFRLEREDGYSFDCKIPPFSLESKPDDLGTPT 416
            |||||||||..||.||..||.:||||||||...|...||
Zfish   334 PSGHMWGTFCFERTDGSHFDVRIPPFSLESNKYDKAPPT 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
POLDIP2	NP_730934.1	YccV-like	72..258	CDD:294919	87/187 (47%)
POLDIP2	NP_730934.1	DUF525	308..390	CDD:282262	68/81 (84%)
poldip2	NP_997879.1	YccV-like	82..208	CDD:294919	85/183 (46%)
poldip2	NP_997879.1	DUF525	242..363	CDD:294703	97/120 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580274
Domainoid	1	1.000	148	1.000	Domainoid score	I4433
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9201
Inparanoid	1	1.050	418	1.000	Inparanoid score	I1782
OMA	1	1.010	-	-		QHG48062
OrthoDB	1	1.010	-	-		D348761at33208
OrthoFinder	1	1.000	-	-		FOG0008192
OrthoInspector	1	1.000	-	-		oto39120
orthoMCL	1	0.900	-	-		OOG6_104714
Panther	1	1.100	-	-	LDO	PTHR14289
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4148
SonicParanoid	1	1.000	-	-		X6156
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.900