Protein Alignment PEK and eif2ak2

DIOPT Version :9

• Sequence 1: NP_649538.1
• Gene: PEK / 40653
• FlyBaseID: FBgn0037327
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: NP_001072537.1
• Gene: eif2ak2 / 779992
• XenbaseID: XB-GENE-1001011
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 542
• Identity: 137/542 - (25%)
• Similarity: 193/542 - (35%)
• Gaps: 232/542 - (42%)

  Fly   585 TAIEATEASTQALLGPVVPMQRPGNRFS--FPPGQAN-QRTISESTTHSGEHYTSRFQSDFELMQ 646
            |..||....:.|.  |.:|::......:  ||..:.. |.|:.|:           |..:|..:.
 Frog   229 TTKEAVPHPSNAT--PTLPLRTRKYELAVKFPNQEKGAQCTLDET-----------FLRNFTEIS 280

  Fly   647 CLGRGGFGVVFEAKNKLDENRYAIKRITLPNKESSRQRVLREARTLASCEHHNIVRYFHSWTETP 711
            .||.||||.|.:||.||....|||||:.|.:|      .::|...||..:|.|||||.||||
 Frog   281 RLGSGGFGTVLKAKCKLANKYYAIKRVKLYDK------CVKEVEALAHLDHPNIVRYNHSWT--- 336

  Fly   712 PTGWQEEEDRKLLAHELSTSIQIETPDDSTMPSLTEQLKEKRQQQLLSWVSDAANSTACSHDFHL 776
                  .||                                                .||
 Frog   337 ------GED------------------------------------------------CCS----- 342

  Fly   777 PGESSLKNIREEYDYDEEEDSLIEFRSESQSAALRAEEEDDTDDDYEEDEEQQGDHEKRHRSSVS 841
              ||:..|                                   .|:
 Frog   343 --ESTYSN-----------------------------------SDF------------------- 351

  Fly   842 IDIHSASFDLKNINYSQHQLVSNSFQIESVRPKSSGSDDANDDNKARRKPLTLALAQNHNNNQNG 906
                                              |.|..:.||
 Frog   352 ----------------------------------SSSPGSKDD---------------------- 360

  Fly   907 SQPTPSSATILNGTVAKPSKVYLYIQMQLCRKESLRDWLRD-NRSETRAAHIGDIFHQIVDAVDY 970
                                 ||:|||:.|.|.:|:.|::. |:.|...:.:  ||.||::.|.|
 Frog   361 ---------------------YLFIQMEWCEKGTLKSWIKHMNKVEKFKSLV--IFRQIIEGVRY 402

  Fly   971 VHLKGLIHRDLKPSNIFFSQDGQIKIGDFGLVTDMADIPNLVAKCGDQSGLPSCARHTQQVGTHL 1035
            :|.||||||||||:||||::|.:||||||||||.|...       .|:..|    ..|:..||..
 Frog   403 IHSKGLIHRDLKPANIFFAEDMKIKIGDFGLVTQMTGE-------ADRQAL----ERTKGRGTKP 456

  Fly  1036 YMSPEQLLGQHYDYKVDIYSLGLIFFELHVYFSTEMERIKTLRSLRDGQYPKDFAVNYPQQYDLL 1100
            ||:||| ..:.|:.:|||:.||||..||...|.|..|:.:..:.||:|:.|..|...||.:..::
 Frog   457 YMAPEQ-YEETYESEVDIFPLGLILVELFYIFKTVHEKQEEWKKLRNGELPPAFVQQYPTEESII 520

  Fly  1101 QQMLSAQPEQRPQTKQLKSQLR 1122
            :::||...::||...|||...:
 Frog   521 KKILSRDRKKRPTAAQLKEYFK 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEK	NP_649538.1	Luminal_EIF2AK3	73..401	CDD:188874
		PKc_like	635..1113	CDD:304357	122/478 (26%)
		S_TKc	<925..1118	CDD:214567	79/193 (41%)
eif2ak2	NP_001072537.1	DSRM_RNAse_III_family	5..71	CDD:380682
		DSRM_EIF2AK2-like	118..183	CDD:380704
		PKc_like	269..541	CDD:389743	127/497 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433474at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11042
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020