Protein Alignment PEK and pkz

DIOPT Version :9

• Sequence 1: NP_649538.1
• Gene: PEK / 40653
• FlyBaseID: FBgn0037327
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: NP_001035466.1
• Gene: pkz / 503703
• ZFINID: ZDB-GENE-050301-2
• Length: 511
• Species: Danio rerio
• Alignment Length: 516
• Identity: 139/516 - (26%)
• Similarity: 210/516 - (40%)
• Gaps: 171/516 - (33%)

  Fly   616 GQANQRTISESTTHSGEHYTSRFQSDFELMQCLGRGGFGVVFEAKNKLDENRYAIKRITLPNKES 680
            |..:.|.:   |:.||...|      |::::.||.||:|.|.:.|:|:|:..||:||:.. |.|:
Zfish   153 GSGSDRKL---TSVSGMSQT------FDVIEELGDGGYGFVCKVKHKIDDKIYAVKRVEF-NSEA 207

  Fly   681 SRQRVLREARTLASCEHHNIVRYFHSWTETPPTGWQEEEDRKLLAHELSTSIQIETPDDSTMPSL 745
            .     .|.:.||..:|.||||||..|.::  ..|...::
Zfish   208 E-----PEVKALARLDHPNIVRYFTCWPDS--DNWMSNQE------------------------- 240

  Fly   746 TEQLKEKRQQQLLSWVSDAANSTACSHDFHLPGESSLKNIREEYDYDEEEDSLIEFRSESQSAAL 810
                           .::.:|:|         |.|:        |.|:..:     ||.|....
Zfish   241 ---------------TNEKSNTT---------GSST--------DTDDTNE-----RSASDDDV- 267

  Fly   811 RAEEEDDTDDDYEEDEEQQGDHEKRHRSSVSIDIHSASFDLKNINYSQHQLVSNSFQIESV-RPK 874
             |::|||.|||..:|              |::.:.|.:|                  .||. ..|
Zfish   268 -ADDEDDDDDDVSDD--------------VTLGMESLTF------------------TESTSAAK 299

  Fly   875 SSGSDDANDDNKARRKPLTLALAQNHNNNQNGSQPTPSSATILNGTVAKPSKVYLYIQMQLCRKE 939
            :||..|..                ||                         :.||:|||:.|...
Zfish   300 ASGQCDPT----------------NH-------------------------RTYLFIQMEFCEGG 323

  Fly   940 SLRDWLRDNR---SETRAAHIGDIFHQIVDAVDYVHLKGLIHRDLKPSNIFFSQDGQIKIGDFGL 1001
            :|..|:.:..   .:.....|..||::|...|:|:|...||||||||.||.|: ||::||||||
Zfish   324 TLTSWIGERNYGGKQRIPLEIHRIFYEISSGVEYIHSNNLIHRDLKPDNILFN-DGKVKIGDFG- 386

  Fly  1002 VTDMADIPNLVAKCGDQSGLPSCARHTQQVGTHLYMSPEQLLGQHYDYKVDIYSLGLIFFELHVY 1066
                     |||...:.||.|  ...:::.||..||||||...::||.|.||:.|||::||:...
Zfish   387 ---------LVAAQKNPSGDP--IERSKRKGTPTYMSPEQENLRNYDEKTDIFPLGLMWFEMLWK 440

  Fly  1067 FSTEMERIKTLRSLRDGQYPKDFAVNYPQQYDLLQQMLSAQPEQRPQTKQLKSQLRNILQL 1127
            .|:.|||.:...:||:.:.|..|...|..:...:::|||..||.||..|.::..|.....|
Zfish   441 ISSGMERAEIWTNLRNQKLPDQFCERYTAENKFIEKMLSVTPEDRPHAKDIRLNLETFFSL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEK	NP_649538.1	Luminal_EIF2AK3	73..401	CDD:188874
		PKc_like	635..1113	CDD:304357	130/481 (27%)
		S_TKc	<925..1118	CDD:214567	75/195 (38%)
pkz	NP_001035466.1	z-alpha	4..70	CDD:295419
		PKc_like	163..495	CDD:304357	134/495 (27%)
		S_TKc	170..491	CDD:214567	131/478 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594083
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1033
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433474at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11042
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850