| Sequence 1: | NP_649538.1 | Gene: | PEK / 40653 | FlyBaseID: | FBgn0037327 | Length: | 1162 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001013725.2 | Gene: | EIF2AK4 / 440275 | HGNCID: | 19687 | Length: | 1649 | Species: | Homo sapiens |
| Alignment Length: | 651 | Identity: | 185/651 - (28%) |
|---|---|---|---|
| Similarity: | 271/651 - (41%) | Gaps: | 199/651 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 568 QRVEREYLVIERHVP-VQTAIEATEASTQALLGPVVPMQR-PGNRFSFPPGQANQRTISESTTHS 630
Fly 631 GEHYTSRFQSDFELMQCLGRGGFGVVFEAKNKLDENRYAIKRITLPNKESSRQ--RVLREARTLA 693
Fly 694 SCEHHNIVRYFHSWTE---------TPP--TGWQEEEDRKLLAHELSTSIQIETPDDSTMPSLTE 747
Fly 748 QLKEKRQQQLLSWVSDAANSTACSHDFHLPGESSLKNIREEYDYDEEEDSLIEFRSESQSAALRA 812
Fly 813 EEEDDTDDDYEEDEEQQGDHEKRHRSSVSIDIHSASFDLKNINYSQHQLVSNSFQIESVRPKSSG 877
Fly 878 SDDA---NDDNKARRKPLTLALAQNHN---NNQNG---SQPTPSSATILNGTVAKPSKVYLYIQM 933
Fly 934 QLCRKESLRDWLRDNRSETRAAHIGDIFHQIVDAVDYVHLKGLIHRDLKPSNIFFSQDGQIKIGD 998
Fly 999 FGLVTD----MADIPNLVAKCGDQSG-----LPSCARHTQQVGTHLYMSPEQLLG---QHYDYKV 1051
Fly 1052 DIYSLGLIFFELHVY-FSTEMERIKTLRSLRDGQYPKDFAVNYPQQYD---------LLQQMLSA 1106
Fly 1107 QPEQRP-QTKQLKSQLRNILQLPHLLSEGQSEQAELAE-----------RARRLSRSRTFSSSSE 1159
Fly 1160 P 1160 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| PEK | NP_649538.1 | Luminal_EIF2AK3 | 73..401 | CDD:188874 | |
| PKc_like | 635..1113 | CDD:304357 | 156/522 (30%) | ||
| S_TKc | <925..1118 | CDD:214567 | 85/215 (40%) | ||
| EIF2AK4 | NP_001013725.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..25 | ||
| RWD | 18..134 | CDD:283440 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 138..158 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 227..256 | ||||
| Pkinase | 296..539 | CDD:278497 | 1/6 (17%) | ||
| PK_eIF2AK_GCN2_rpt1 | 299..538 | CDD:270914 | 1/5 (20%) | ||
| STKc_EIF2AK4_GCN2_rpt2 | 583..999 | CDD:270948 | 159/529 (30%) | ||
| S_TKc | 590..1001 | CDD:214567 | 158/533 (30%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 660..750 | 25/170 (15%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 765..788 | 7/30 (23%) | |||
| Histidyl-tRNA synthetase-like | 1022..1493 | 5/20 (25%) | |||
| class_II_aaRS-like_core | 1061..1385 | CDD:294192 | |||
| HisS | 1065..1490 | CDD:223202 | |||
| HGTP_anticodon | 1395..1641 | CDD:294191 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D433474at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.920 | |||||