Protein Alignment PEK and hri2

DIOPT Version :9

• Sequence 1: NP_649538.1
• Gene: PEK / 40653
• FlyBaseID: FBgn0037327
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: NP_593146.1
• Gene: hri2 / 2541943
• PomBaseID: SPAC222.07c
• Length: 639
• Species: Schizosaccharomyces pombe
• Alignment Length: 647
• Identity: 170/647 - (26%)
• Similarity: 262/647 - (40%)
• Gaps: 167/647 - (25%)

  Fly   570 VEREYLVIERHVPVQT--AIEATEASTQALLGP-------VVPMQRPGNRFSFPPGQANQRTISE 625
            |...|.....|:.:|.  ||...:|..:.|..|       ..|.:...::||.......|....:
pombe    89 VRSNYQDALHHLILQAREAIRLDDAEERLLALPDPTNVFEKFPQETALSKFSVDGLNVRQFRFRD 153

  Fly   626 STTHSG-EHYTSRFQSDFELMQCLGRGGFGVVFEAKNKLDENRYAIKRITLPNKESSRQRVLREA 689
            .|..|. :...||:..|||....|||||||.|:..:||:|...||:|:|....::.|..::.||.
pombe   154 LTLESWLQSRNSRYIEDFEEYSLLGRGGFGSVYHVRNKIDGAEYAMKKINSTFQQMSYSKIFREI 218

  Fly   690 RTLASCEHHNIVRYFHSWTETPPTGWQEEEDRKLLAHELSTSIQIETPDDSTMPSLTEQLKEKRQ 754
            :.||..:|.|::|||.||.|:                         |.:.:.||.    :..|..
pombe   219 KCLAKMDHPNVIRYFSSWVES-------------------------TTEATQMPI----VMSKNS 254

  Fly   755 QQLLSWVSDAANSTACSHDFHLPGESSLKNIREEYDYDEEEDSLIEFRSESQSAALRAEEEDDTD 819
            .::|                   |.||..::       ...||:|  ...::|:||       ||
pombe   255 SRVL-------------------GTSSYCDV-------NGMDSII--FEPTESSAL-------TD 284

  Fly   820 DD-YEEDEEQQGDHEKRHRSSVSIDIHSASFDLKNINYSQHQLVSNSFQIESVRPKSSGSDDAND 883
            |. :.||...:.......:||.|....|::|:                .:||.|       :.:|
pombe   285 DILFAEDPGTESIISTSRKSSYSSTTESSNFE----------------NLESPR-------NLHD 326

  Fly   884 DNKARRKPLTLALAQNHNNNQNGSQPTPSSATILNGTVAKPSKVYLYIQMQLCRKESLRDWLRDN 948
            .|.:.....|: |..:::::.:.|:..|:.:.|            :|||||||..:.....:|.|
pombe   327 SNVSTFNNTTI-LDDDYSSSMHISKTGPTHSFI------------IYIQMQLCFDDLESYLIRRN 378

  Fly   949 R-------SETRAAHIGDIFHQIVDAVDYVHLKG--LIHRDLKPSNIFFSQD-----GQI----- 994
            .       .|....|. |:|..|::.|.||| :|  |||||:||||||.::.     |.:
pombe   379 HFLSFPLCKEQIQLHT-DLFRMIINGVMYVH-EGVNLIHRDIKPSNIFLAKSLPEDRGSVPLISY 441

  Fly   995 ------------KIGDFGLVTDMADIPNLVAKCGDQSGLPSCARHTQQVGTHLYMSPEQL---LG 1044
                        ||||||||.:............:::.||:....||.:||..|.:||.|   ..
pombe   442 NDKNDLKEYITPKIGDFGLVVENKKNTETALSFLERNHLPNLQDETQHIGTATYAAPELLDAMSS 506

  Fly  1045 QH--YDYKVDIYSLGLIFFELHVYFSTEMERIKTLRSLRDGQYPKDFAVNYPQQYDLLQQMLSAQ 1107
            ||  :..|:|.:|||::.|||...|.|.|||...|:.||.|..|::|...:..:..|:..|.:..
pombe   507 QHNKFTKKIDTFSLGMVLFELLHPFQTNMERATKLQDLRRGNLPEEFVEQHICESSLILWMTAKD 571

  Fly  1108 PEQRPQTKQLKS------------QLRNILQLPHLLSEGQ-----SEQAELAERARRLSRSR 1152
            |.:||...::.:            .:.||:...||..|.|     .|...|.|:...| |||
pombe   572 PTKRPSLLEVLNCGLLLPNQVSMPNISNIVSTNHLDVETQMKLIMDENQRLREQIAVL-RSR 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEK	NP_649538.1	Luminal_EIF2AK3	73..401	CDD:188874
		PKc_like	635..1113	CDD:304357	141/514 (27%)
		S_TKc	<925..1118	CDD:214567	75/228 (33%)
hri2	NP_593146.1	STKc_EIF2AK	164..585	CDD:270898	142/522 (27%)
		S_TKc	171..583	CDD:214567	139/513 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	67	1.000	Domainoid score	I2751
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910