Protein Alignment PEK and pkr2

DIOPT Version :9

• Sequence 1: NP_649538.1
• Gene: PEK / 40653
• FlyBaseID: FBgn0037327
• Length: 1162
• Species: Drosophila melanogaster
• Sequence 2: XP_031758367.1
• Gene: pkr2 / 100141482
• XenbaseID: XB-GENE-1011407
• Length: 431
• Species: Xenopus tropicalis
• Alignment Length: 615
• Identity: 155/615 - (25%)
• Similarity: 223/615 - (36%)
• Gaps: 245/615 - (39%)

  Fly   561 IFMGQRNQRVEREYLVIER-----------HVPVQTAI--------------EATEASTQALLGP 600
            :|..:||  :..|:.:|.:           |:.::..|              ||......||...
 Frog     1 MFCAKRN--LHYEFKLISKTEPPNDPWFTVHLYIENEIFGEGQGRSRKAADKEAARTGLAALQNR 63

  Fly   601 VVPMQ--RPGNRFSFPP---------GQANQRTISESTTHSGEHYTSRF-----------QS--- 640
            ..|.|  :|....|:.|         ..::|...|::|..|.|..:|..           ||
 Frog    64 GKPSQARQPSAADSWDPVPSSGSNSTSNSSQSLGSDATEGSSERSSSHTTQSTVPTTNVEQSPLR 128

  Fly   641 DFELMQCLGRGGFGVVFEAKNKLDENRYAIKRITLPNKESSRQRVLREARTLASCEHHNIVRYFH 705
            :||.:..|..||||:|::|...:|.|.||:|::.:.|     ::...|.:.||..:|.||||||:
 Frog   129 EFENVTELSSGGFGIVYKAWKPMDLNYYAVKKVKMYN-----EKCKSEVQALARLDHPNIVRYFN 188

  Fly   706 SWTETPPTGWQEEEDRKLLAHELSTSIQIETPDDSTMPSLTEQLKEKRQQQLLSWVSDAANSTAC 770
            |||.              :.:.|.||
 Frog   189 SWTG--------------MDYFLDTS--------------------------------------- 200

  Fly   771 SHDFHLPGESSLKNIREEYDYDEEEDSLIEFRSESQSAALRAEEEDDTDDDYEEDEEQQGDHEKR 835
                .|...||..|                  ::|.:.:|....||.:.|
 Frog   201 ----SLSSSSSSNN------------------NQSTNVSLFRTREDCSSD--------------- 228

  Fly   836 HRSSVSIDIHSASFDLKNINYSQHQLVSNSFQIESVRPKSSGSDDANDDNKARRKPLTLALAQNH 900
                                               .|..||.:|..|:
 Frog   229 -----------------------------------TRNSSSDTDGRNE----------------- 241

  Fly   901 NNNQNGSQPTPSSATILNGTVAKPSKVYLYIQMQLCRKESLRDWLRDNRSETRAAHIGDIFHQIV 965
                                       ||||||:.|....||:|:|:.:...:...: |||.|||
 Frog   242 ---------------------------YLYIQMEFCENGDLRNWIREMKEVDKKNSL-DIFWQIV 278

  Fly   966 DAVDYVHLKGLIHRDLKPSNIFFSQDGQIKIGDFGLVTDMADIPNLVAKCGDQSGLPSCARHTQQ 1030
            ..|.|:|.:.||||||||.|||||:|.::|||||||||.:.           ..|.......|..
 Frog   279 KGVAYIHSQKLIHRDLKPENIFFSKDKKVKIGDFGLVTQIF-----------SEGSTKALLRTHG 332

  Fly  1031 VGTHLYMSPEQLLGQH----YDYKVDIYSLGLIFFELHVYFSTEMERIKTLRSLRDGQYPKDFAV 1091
            .||:.||:|||   ||    |:.:|||::||||..||...|.||.||...|..:|:.|:||.|..
 Frog   333 TGTYPYMAPEQ---QHKKTNYNSEVDIFALGLILVELLCIFGTEHERRDELMKIRNCQFPKAFVA 394

  Fly  1092 NYPQQYDLLQQMLSAQPEQRPQTKQLKSQL 1121
            .||.:...::.|||..|:.||...:||:.|
 Frog   395 KYPCEISTIRLMLSRDPKNRPAAIKLKAFL 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEK	NP_649538.1	Luminal_EIF2AK3	73..401	CDD:188874
		PKc_like	635..1113	CDD:304357	130/495 (26%)
		S_TKc	<925..1118	CDD:214567	83/196 (42%)
pkr2	XP_031758367.1	DSRM_RNAse_III_family	2..62	CDD:380682	11/61 (18%)
		PKc_like	129..424	CDD:419665	130/483 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D433474at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11042
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4549
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050