Protein Alignment CG12147 and YCK2

DIOPT Version :9

• Sequence 1: NP_649536.1
• Gene: CG12147 / 40651
• FlyBaseID: FBgn0037325
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_014245.1
• Gene: YCK2 / 855568
• SGDID: S000005098
• Length: 546
• Species: Saccharomyces cerevisiae
• Alignment Length: 434
• Identity: 149/434 - (34%)
• Similarity: 227/434 - (52%)
• Gaps: 58/434 - (13%)

  Fly    63 IVAGKYRLLKRIGNGSFGELFQAEGLKYHEKVAIKLESSTVKHPLLPREARIYGILQGGLGIPHV 127
            ||...|::.|:||.||||.||:...:.....||||.|....:.|.|..|.|.|.||.|..|||..
Yeast    71 IVGLHYKIGKKIGEGSFGVLFEGTNMINGLPVAIKFEPRKTEAPQLKDEYRTYKILAGTPGIPQE 135

  Fly   128 KHYATEGAYNVMVMDLLGPTLEDLLNLCSRSFSMKTTLMLADQILARVELLHRRCFIHRDIKPDN 192
            .::..||.:|::|:|||||:||||.:.|.|.||:||.:.:|.|::..:|.||....|:|||||||
Yeast   136 YYFGQEGLHNILVIDLLGPSLEDLFDWCGRRFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDN 200

  Fly   193 FLMGL--NRHQTQVYMIDFGLAKKFYSLRTQKHIGYTENRDLVGTARYASVRAHYA-EQSRRDDL 254
            ||:|.  .....:|::||||:||::...:|::||.|.|.:.|.|||||.|:..|.. |||||||:
Yeast   201 FLIGRPGQPDANKVHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDM 265

  Fly   255 ESVGYLLLYFQRGRLPWQGIRAQSQAQKYEKIAEYKANIPLQQLCSGLPVEFFMYLKYCRKLHFA 319
            |::|::..||.||:|||||::|.:..||||||.|.|....:..|..|||::|..||:..|.|.|.
Yeast   266 EAMGHVFFYFLRGQLPWQGLKAPNNKQKYEKIGEKKRLTNVYDLAQGLPIQFGRYLEIVRNLSFE 330

  Fly   320 EKPDYVYLQQLFKVLFRNQYKVCDFLFDWVVL-----------------------------KR-- 353
            |.|||...:.|...:..:..:..|..:||:.|                             ||
Yeast   331 ETPDYEGYRMLLLSVLDDLGETADGQYDWMKLNGGRGWDLSINKKPNLHGYGHPNPPNEKSKRHR 395

  Fly   354 ------ESPE------QQSQQKGRERDRGGKRNVVVQKERHRNKDRDSDTQRCRIKNGGDLLEIE 406
                  .||:      ||.||:..:.....:....||:::.:.........|.:::......: |
Yeast   396 SKNHQYSSPDHHHHYNQQQQQQQAQAQAQAQAQAKVQQQQLQQAQAQQQANRYQLQPDDSHYD-E 459

  Fly   407 ENEST----TGEDPNEDKPQKKHGKACSCSYHLQKKRLQDRDRR 446
            |.|::    |..:..:.:.|:|:.:.       |:|::|.:.::
Yeast   460 EREASKLDPTSYEAYQQQTQQKYAQQ-------QQKQMQQKSKQ 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12147	NP_649536.1	STKc_CK1	67..331	CDD:270918	122/266 (46%)
		SPS1	67..>306	CDD:223589	112/241 (46%)
YCK2	NP_014245.1	STKc_CK1_fungal	75..351	CDD:271029	123/275 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344360
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700